Patents by Inventor Maxwell D. Reeve

Maxwell D. Reeve has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100029941
    Abstract: Described herein are methods for making chiral derivatives of 3-aminopiperidine, including the production of such derivatives in quantities exceeding 1 kilogram. The chiral 3-aminopiperidine derivatives include (R)-3-aminopiperidine derivatives which may be used to synthesize inhibitors of Dipeptidyl Peptidase IV. (R)-3-Aminopiperidine dihydrochloride is prepared by reducing (R)-3-aminopiperidin-2-one hydrochloride with lithium aluminum hydride. The preparation of (R)-3-aminopiperidin-2-one hydrochloride starting from (R)-methyl-2,5-diaminopentanoate dihydrochloride or (R)-2,5-diaminopentanoic acid hydrochloride is also described.
    Type: Application
    Filed: March 26, 2007
    Publication date: February 4, 2010
    Inventors: Michael B. Wallace, Jeremy Cody, Richard S. Fornicola, Silvina Garcia-Rubio, Philip B. Kisanga, Maxwell D. Reeve, Chandra Wilson