Patents by Inventor May Daher

May Daher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LARGE-SCALE COMBINED CAR TRANSDUCTION AND CRISPR GENE EDITING OF NK CELLS
    Publication number: 20220389383
    Abstract: Embodiments of the disclosure encompass methods and compositions for producing engineered natural killer (NK) cells. The disclosure concerns large-scale processes for producing NK cells that are engineered to have disruption of expression of one or more genes, such as using CRISPR, and also engineered express at least one heterologous antigen receptor. Specific embodiments include particular parameters for the process.
    Type: Application
    Filed: November 25, 2020
    Publication date: December 8, 2022
    Inventors: Katy REZVANI, Rafet BASAR, May DAHER, David MARIN COSTA
  • NATURAL KILLER CELLS ENGINEERED TO EXPRESS CHIMERIC ANTIGEN RECEPTORS WITH IMMUNE CHECKPOINT BLOCKADE
    Publication number: 20210230548
    Abstract: Provided herein are methods for producing NK cells expressing chimeric antigen receptors and having no expression of CISH. Further provided are methods for treating diseases by administering the CAR NK cells.
    Type: Application
    Filed: May 3, 2019
    Publication date: July 29, 2021
    Inventors: May Daher, Rafet Basar, Elizabeth Shpall, Katy Rezvani