Patents by Inventor Maya Farha

Maya Farha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240033285
    Abstract: Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one embodiment, provided herein are methods for treating a microbial infection comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent. Also provided herein are methods of screening for antimicrobial compounds.
    Type: Application
    Filed: September 28, 2023
    Publication date: February 1, 2024
    Inventors: Eric Brown, Maya Farha, Craig MacNair, Jonathan Stokes
  • Publication number: 20230390328
    Abstract: Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one embodiment, provided herein are methods for treating a microbial infection comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent. Also provided herein are methods of screening for antimicrobial compounds.
    Type: Application
    Filed: August 21, 2023
    Publication date: December 7, 2023
    Inventors: Eric Brown, Maya Farha, Craig MacNair
  • Patent number: 11779595
    Abstract: Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one embodiment, provided herein are methods for treating a microbial infection comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent. Also provided herein are methods of screening for antimicrobial compounds.
    Type: Grant
    Filed: January 25, 2021
    Date of Patent: October 10, 2023
    Assignee: McMaster University
    Inventors: Eric Brown, Maya Farha, Craig MacNair, Jonathan Stokes
  • Patent number: 11400106
    Abstract: Provided herein are methods and compositions useful for inhibiting microbe growth. The methods can comprise contacting the microbe with an antimicrobial agent and bicarbonate. In some embodiments, provided herein are methods for treating or preventing a microbial infection, comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: August 2, 2022
    Assignee: McMaster University
    Inventors: Eric Brown, Maya Farha, Craig MacNair, Lindsey Carfrae
  • Publication number: 20220017482
    Abstract: Provided herein are synthetic compounds useful for inhibiting bacterial growth and uses thereof. Also provided are pharmaceutical compositions. The compounds and pharmaceutical compositions are useful for inhibiting growth of a bacterium or treating or preventing a bacterial infection.
    Type: Application
    Filed: November 20, 2019
    Publication date: January 20, 2022
    Inventors: Eric Brown, Omar M Elhalfawy, Maya Farha, Jakob Magolan, Robert Gale
  • Publication number: 20210220393
    Abstract: Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one embodiment, provided herein are methods for treating a microbial infection comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent. Also provided herein are methods of screening for antimicrobial compounds.
    Type: Application
    Filed: January 25, 2021
    Publication date: July 22, 2021
    Inventors: Eric Brown, Maya Farha, Craig MacNair, Jonathan Stokes
  • Publication number: 20210145854
    Abstract: Provided herein are methods and compositions useful for inhibiting microbe growth. The methods can comprise contacting the microbe with an antimicrobial agent and bicarbonate. In some embodiments, provided herein are methods for treating or preventing a microbial infection, comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent.
    Type: Application
    Filed: January 29, 2021
    Publication date: May 20, 2021
    Inventors: Eric Brown, Maya Farha, Craig MacNair, Lindsey Carfrae
  • Patent number: 10940163
    Abstract: Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one embodiment, provided herein are methods for treating a microbial infection comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent. Also provided herein are methods of screening for antimicrobial compounds.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: March 9, 2021
    Assignee: McMaster University
    Inventors: Eric Brown, Maya Farha, Craig MacNair, Jonathan Stokes
  • Publication number: 20180243333
    Abstract: Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one embodiment, provided herein are methods for treating a microbial infection comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent. Also provided herein are methods of screening for antimicrobial compounds.
    Type: Application
    Filed: February 2, 2018
    Publication date: August 30, 2018
    Applicant: McMaster University
    Inventors: Eric Brown, Maya Farha, Craig MacNair, Jonathan Stokes
  • Publication number: 20140088069
    Abstract: An antibacterial composition is provided including a combination of a ?-lactam antibiotic that has a binding affinity for bacterial penicillin-binding protein 2; and a non-antibiotic compound which may be a thienopyridine or a non-thienopyridine compound. A method of treatment using the composition is also provided.
    Type: Application
    Filed: November 29, 2013
    Publication date: March 27, 2014
    Inventors: Eric D. Brown, Maya Farha, Alexander Leung, Gerry Wright, Kalinka Koteva, Ted Sewell, Linda Ejim