Patents by Inventor Maya Tiemeyer

Maya Tiemeyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the purification of a growth factor protein
    Patent number: 10214575
    Abstract: A method of purifying a Growth Factor Protein in a purification sequence employing chromatography is provided. The method comprises performing at least one chromatography step using a multimodal resin, binding the Growth Factor Protein to the multimodal resin at a pH from 4 to 6.2, and eluting the Growth Factor Protein at a pH in the range of from 5.5 to 6.5. The elution of Growth Factor Protein is improved by addition of arginine and/or NaCl in the eluting buffer. Optionally the multimodal resin step is followed by a yeast derived affinity ligand resin step, which results in a purity of the product greater than 90%.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: February 26, 2019
    Assignee: OCTAPHARMA AG
    Inventors: Gustav Gilljam, Stefan Winge, Maya Tiemeyer
  • PROCESS FOR THE PURIFICATION OF A GROWTH FACTOR PROTEIN
    Publication number: 20170051028
    Abstract: A process of purifying a Growth Factor Protein in a purification sequence employing chromatography characterized in that at least one chromatography is performed using a multimodal resin the Growth Factor Protein binds to the multimodal resin at a pH between 4 to 6.2, and the Growth Factor Protein is eluting at a pH >6.3, and the elution of Growth Factor Protein is improved by addition of arginine and/or NaCl to the eluting buffer. The multimodal resin step is followed by a yeast derived affinity ligand resin step, which results of a purity of the product >90%.
    Type: Application
    Filed: September 2, 2016
    Publication date: February 23, 2017
    Applicant: OCTAPHARMA AG
    Inventors: Gustav Gilljam, Stefan Winge, Maya Tiemeyer
  • Process for the purification of a growth factor protein
    Patent number: 9453045
    Abstract: A process of purifying the Growth Factor Protein G-CSF (Granulocyte Colony Stimulating Factor) in a purification sequence employing chromatography, comprising binding the G-CSF to Capto MMC™, which is a multimodal resin that comprises a negatively charged 2-(benzoylamino) butanoic acid ligand, at a pH from 4 to 6.2; and eluting the G-CSF at a pH greater than 6.3.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: September 27, 2016
    Assignee: OCTAPHARMA AG
    Inventors: Gustav Gilljam, Stefan Winge, Maya Tiemeyer
  • Recombinantly produced human factor VIII and IX
    Patent number: 9120873
    Abstract: A recombinant human factor VIII or IX protein having a human glycosylation pattern but the protein is devoid of N-glycolylneuraminic acid and/or the carbohydrate group Gal?-3Gal.
    Type: Grant
    Filed: August 21, 2009
    Date of Patent: September 1, 2015
    Assignee: Octapharma AG
    Inventors: Helena Sandberg, Peter Stenlund, Carola Schröder, Elisabeth Casademunt, Maya Tiemeyer
  • PROCESS FOR THE PURIFICATION OF A GROWTH FACTOR PROTEIN
    Publication number: 20130096279
    Abstract: A process of purifying a Growth Factor Protein in a purification sequence employing chromatography characterized in that at least one chromatography is performed using a multimodal resin the Growth Factor Protein binds to the multimodal resin at a pH between 4 to 6.2, and the Growth Factor Protein is eluting at a pH>6.3, and the elution of Growth Factor Protein is improved by addition of arginine and/or NaCl to the eluting buffer. The multimodal resin step is followed by a yeast derived affinity ligand resin step, which results of a purity of the product>90%.
    Type: Application
    Filed: March 30, 2011
    Publication date: April 18, 2013
    Applicant: OCTAPHARMA AG
    Inventors: Gustav Gilljam, Stefan Winge, Maya Tiemeyer
  • RECOMBINANTLY PRODUCED HUMAN FACTOR VIII AND IX
    Publication number: 20110262424
    Abstract: A recombinant human factor VIII or IX protein having a human glycosylation pattern but the protein is devoid of N-glycolylneuraminic acid and/or the carbohydrate group Gal?-3Gal.
    Type: Application
    Filed: August 21, 2009
    Publication date: October 27, 2011
    Inventors: Helena Sandberg, Peter Stenlund, Carola Schröder, Elisabeth Casademunt, Maya Tiemeyer