Patents by Inventor Mayank Srivastava
Mayank Srivastava has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11480580Abstract: Disclosed herein is a chemo-proteomic probe for labelling and monitoring a live microbe interacting with a host cell and for qualitative and quantitative analyses of those proteins involved during a microbe infects the host cell. This probe comprises a functional group for conjugating to a surface protein of a live microbe under a physiological condition; a photo-reactive group for covalent cross-linking to an interacting cell protein of a host; and a tag for isolating the cross-linked complex of the surface protein of said live microbe and the interacting protein of a host cell for qualitative and quantitative proteomics analyses. The probe may further comprise a visualization tag. This technology takes advantage of the high throughput feature of mass spectrometry analysis and combines it with a uniquely designed chemistry to achieve high efficient isolation and analysis of host cell proteins interacting with a pathogen at different stages of an infection.Type: GrantFiled: April 17, 2020Date of Patent: October 25, 2022Assignee: Purdue Research FoundationInventors: Weiguo Andy Tao, Ying Zhang, Mayank Srivastava
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Patent number: 11141495Abstract: Provided are aromatic compounds, phospholipid-polymer-aromatic conjugates comprising the aromatic compounds, and liposome compositions including the phospholipid-polymer-aromatic conjugates. The liposomal compositions may be useful for imaging of Alzheimer's Disease, for example, imaging of the amyloid-? plaque deposits characteristic of Alzheimer's Disease.Type: GrantFiled: February 14, 2020Date of Patent: October 12, 2021Assignee: Texas Children's HospitalInventors: Ananth V. Annapragada, Eric A. Tanifum, Mayank Srivastava
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Publication number: 20200333354Abstract: Disclosed herein is a chemo-proteomic probe for labelling and monitoring a live microbe interacting with a host cell and for qualitative and quantitative analyses of those proteins involved during a microbe infects the host cell. This probe comprises a functional group for conjugating to a surface protein of a live microbe under a physiological condition; a photo-reactive group for covalent cross-linking to an interacting cell protein of a host; and a tag for isolating the cross-linked complex of the surface protein of said live microbe and the interacting protein of a host cell for qualitative and quantitative proteomics analyses. The probe may further comprise a visualization tag. This technology takes advantage of the high throughput feature of mass spectrometry analysis and combines it with a uniquely designed chemistry to achieve high efficient isolation and analysis of host cell proteins interacting with a pathogen at different stages of an infection.Type: ApplicationFiled: April 17, 2020Publication date: October 22, 2020Applicant: Purdue Research FoundationInventors: Weiguo Andy Tao, Ying Zhang, Mayank Srivastava
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Publication number: 20200179540Abstract: Provided are aromatic compounds, phospholipid-polymer-aromatic conjugates comprising the aromatic compounds, and liposome compositions including the phospholipid-polymer-aromatic conjugates. The liposomal compositions may be useful for imaging of Alzheimer's Disease, for example, imaging of the amyloid-? plaque deposits characteristic of Alzheimer's Disease.Type: ApplicationFiled: February 14, 2020Publication date: June 11, 2020Inventors: Ananth V. Annapragada, Eric A. Tanifum, Mayank Srivastava
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Publication number: 20200069820Abstract: Provided are aromatic compounds, phospholipid-polymer-aromatic conjugates comprising the aromatic compounds, and liposome compositions including the phospholipid-polymer-aromatic conjugates. The liposomal compositions may be useful for imaging of Alzheimer's Disease, for example, imaging of the amyloid-? plaque deposits characteristic of Alzheimer's Disease.Type: ApplicationFiled: November 8, 2019Publication date: March 5, 2020Inventors: Ananth Annapragada, Eric A. Tanifum, Mayank Srivastava
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Patent number: 10537649Abstract: Provided are aromatic compounds, phospholipid-polymer-aromatic conjugates comprising the aromatic compounds, and liposome compositions including the phospholipid-polymer-aromatic conjugates. The liposomal compositions may be useful for imaging of Alzheimer's Disease, for example, imaging of the amyloid-? plaque deposits characteristic of Alzheimer's Disease.Type: GrantFiled: December 1, 2016Date of Patent: January 21, 2020Assignee: TEXAS CHILDREN'S HOSPITALInventors: Ananth Annapragada, Eric A. Tanifum, Mayank Srivastava
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Patent number: 9744251Abstract: Provided are aromatic compounds, phospholipid-polymer-aromatic conjugates comprising the aromatic compounds, and liposome compositions including the phospholipid-polymer-aromatic conjugates. The liposomal compositions may be useful for imaging of Alzheimer's Disease, for example, imaging of the amyloid-? plaque deposits characteristic of Alzheimer's Disease.Type: GrantFiled: October 8, 2015Date of Patent: August 29, 2017Inventors: Ananth V. Annapragada, Eric A. Tanifum, Mayank Srivastava
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Publication number: 20170080111Abstract: Provided are aromatic compounds, phospholipid-polymer-aromatic conjugates comprising the aromatic compounds, and liposome compositions including the phospholipid-polymer-aromatic conjugates. The liposomal compositions may be useful for imaging of Alzheimer's Disease, for example, imaging of the amyloid-? plaque deposits characteristic of Alzheimer's Disease.Type: ApplicationFiled: December 1, 2016Publication date: March 23, 2017Inventors: Ananth Annapragada, Eric A. Tanifum, Mayank Srivastava
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Publication number: 20160101197Abstract: Provided are aromatic compounds, phospholipid-polymer-aromatic conjugates comprising the aromatic compounds, and liposome compositions including the phospholipid-polymer-aromatic conjugates. The liposomal compositions may be useful for imaging of Alzheimer's Disease, for example, imaging of the amyloid-? plaque deposits characteristic of Alzheimer's Disease.Type: ApplicationFiled: October 8, 2015Publication date: April 14, 2016Inventors: Ananth V. Annapragada, Eric A. Tanifum, Mayank Srivastava
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Patent number: 9278068Abstract: Vesicle compositions are provided that comprise a therapeutic compound. The vesicle compositions may be capable of releasing the therapeutic compound in response to the presence of an external trigger. The vesicle compositions may comprise a plurality of biocompatible vesicles. The biocompatible vesicles may comprise a therapeutic compound for treatment of a patient in need thereof, and one or more cross-linkages between two or more of the biocompatible vesicles, each cross-linkage comprising a chemical sensing moiety and a sensed moiety. In some embodiments, the therapeutic compound may be any compound that provides palliative, curative, or otherwise beneficial effects to a patent.Type: GrantFiled: February 10, 2014Date of Patent: March 8, 2016Assignees: Board of Regents of the University of Texas System, Sensulin, LLCInventors: Ananth Annapragada, Indrani Dasgupta, Eric Tanifum, Mayank Srivastava, Mostafa Analoui
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Publication number: 20140227349Abstract: Vesicle compositions are provided that comprise a therapeutic compound. The vesicle compositions may be capable of releasing the therapeutic compound in response to the presence of an external trigger. The vesicle compositions may comprise a plurality of biocompatible vesicles. The biocompatible vesicles may comprise a therapeutic compound for treatment of a patient in need thereof, and one or more cross-linkages between two or more of the biocompatible vesicles, each cross-linkage comprising a chemical sensing moiety and a sensed moiety. In some embodiments, the therapeutic compound may be any compound that provides palliative, curative, or otherwise beneficial effects to a patent.Type: ApplicationFiled: February 10, 2014Publication date: August 14, 2014Applicants: Board of Regents of the University of Texas System, Sensulin LLCInventors: Ananth Annapragada, Indrani Dasgupta, Eric Tanifum, Mayank Srivastava, Mostafa Analoui
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Patent number: 8679531Abstract: Vesicle compositions are provided that comprise a therapeutic compound. The vesicle compositions may be capable of releasing the therapeutic compound in response to the presence of an external trigger. The vesicle compositions may comprise a plurality of biocompatible vesicles. The biocompatible vesicles may comprise a therapeutic compound for treatment of a patient in need thereof, and one or more cross-linkages between two or more of the biocompatible vesicles, each cross-linkage comprising a chemical sensing moiety and a sensed moiety. In some embodiments, the therapeutic compound may be any compound that provides palliative, curative, or otherwise beneficial effects to a patent.Type: GrantFiled: March 2, 2012Date of Patent: March 25, 2014Inventors: Ananth Annapragada, Indrani Dasgupta, Eric Tanifum, Mayank Srivastava, Mostafa Analoui
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Publication number: 20120231067Abstract: Vesicle compositions are provided that comprise a therapeutic compound. The vesicle compositions may be capable of releasing the therapeutic compound in response to the presence of an external trigger. The vesicle compositions may comprise a plurality of biocompatible vesicles. The biocompatible vesicles may comprise a therapeutic compound for treatment of a patient in need thereof, and one or more cross-linkages between two or more of the biocompatible vesicles, each cross-linkage comprising a chemical sensing moiety and a sensed moiety. In some embodiments, the therapeutic compound may be any compound that provides palliative, curative, or otherwise beneficial effects to a patent.Type: ApplicationFiled: March 2, 2012Publication date: September 13, 2012Applicants: BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, SENSULIN, LLCInventors: Ananth Annapragada, Indrani Dasgupta, Eric Tanifum, Mayank Srivastava, Mostafa Analoui