Patents by Inventor McManaman, James L.

McManaman, James L. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to prepare a neurotrophic composition
    Patent number: 4923696
    Abstract: The present invention is based on the discovery that amyotrophic lateral sclerosis (ALS), Parkinson disease and Alzheimer disease are due to lack of disorder-specific neurotrophic factors. Specific neurotrophic factors of .about.20-22 kD and .about.16-18 kD have been isolated from rat and human skeletal motor neurons, respectively, and purified. With tissue culture, the presence or absence of the specific neurotrophic factors provided herein can be assessed in ALS. If there is a deficiency, extracted and purified neurotrophic factors specific to the motor neuronal network or system can be administered to ALS-affected individuals.
    Type: Grant
    Filed: April 22, 1988
    Date of Patent: May 8, 1990
    Assignee: Baylor College of Medicine
    Inventors: Stanley H. Appel, McManaman, James L., Kenneth W. Vaca