Abstract: Disclosed are systems and methods for dynamic application testing. One or more processing circuits receive an application package with an application and authentication information corresponding with group permission states. The one or more processing circuits authenticate access based on the authentication information and group permission states, model testing parameters, and generate indications, with at least one indication corresponding to a simulated breach. The one or more processing circuits retrieve testing parameters via an API, simulate the breach by providing breach data to update a testing parameters state from a first to a second state, and generate an indication for the update. The one or more processing circuits generate and provide a token with authentication information and the indication to a monitoring system, receive an alert identifier from the monitoring system, and generate a data package including the testing parameter, alert identifier, and indication.

Abstract: This disclosure relates to heterobifunctional compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the heterobifunctional compounds, and to methods of use the heterobifunctional compounds for the treatment of certain disease in a subject in need thereof. The disclosure also relates to methods for identifying such heterobifunctional compounds.

Abstract: This disclosure relates to heterobifunctional compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the heterobifunctional compounds, and to methods of use the heterobifunctional compounds for the treatment of certain disease in a subject in need thereof. The disclosure also relates to methods for identifying such heterobifunctional compounds.