Abstract: Systems and methods are disclosed herein for tire condition monitoring, and more particularly for detecting slow leakage of inflation pressure. Data acquisition devices (e.g., tire pressure monitoring system sensors) are mounted onboard motor vehicles and collect data samples corresponding to at least tire inflation pressure. The collected data samples may e.g. only be transmitted for analysis while the motor vehicle is in a fleet yard or otherwise wherein the contained air temperature effectively matches an ambient temperature. A time elapsed is calculated from a first data sample within a defined sampling period, and a statistical model is applied for at least the data samples corresponding to inflation pressure with respect to the time elapsed. A tire slow leak event is ascertained based on an evaluated amount of decrease in the inflation pressure from the statistical model, and an output signal is selectively generated corresponding to the ascertained slow leak event.