Patents by Inventor Mean-Shine Chen

Mean-Shine Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant baculovirus vector and uses thereof
    Patent number: 9328147
    Abstract: Disclosed herein is a recombinant viral construct and its uses thereof. The recombinant viral construct is capable of simultaneously expressing three exogenous proteins, including a classical swine fever virus (CSFV) antigen, a porcine circovirus type 2 (PCV2) antigen, and an immunomodulatory protein. The recombinant viral construct is hence useful as a bio-tool for simultaneously producing multiple antigens of a bi-subunit vaccine.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: May 3, 2016
    Assignee: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Tzong-Yuan Wu, Mean-Shine Chen, Chao-Yi Teng, Ying-Ju Chen
  • NOVEL RECOMBINANT BACULOVIRUS VECTOR AND USES THEREOF
    Publication number: 20160068575
    Abstract: Disclosed herein is a recombinant viral construct and its uses thereof. The recombinant viral construct is capable of simultaneously expressing three exogenous proteins, including a classical swine fever virus (CSFV) antigen, a porcine circovirus type 2 (PCV2) antigen, and an immunomodulatory protein. The recombinant viral construct is hence useful as a bio-tool for simultaneously producing multiple antigens of a bi-subunit vaccine.
    Type: Application
    Filed: September 5, 2014
    Publication date: March 10, 2016
    Inventors: TZONG-YUAN WU, MEAN-SHINE CHEN, CHAO-YI TENG, YING-JU CHEN
  • Hybrid baculovirus and uses thereof
    Patent number: 9267113
    Abstract: Disclosed herein is an Autographa californica multiple nucleopolyhedrovirus (AcMNPV) based hybrid baculovirus and its uses thereof. The AcMNPV based hybrid baculovirus is capable of infecting different hosts, and comprises Maruca vitrata multiple nucleopolyhedrovirus (MaviMNPV) genes of lef1, orf1629, pk1, CDS1, CDS2, and lef2; and AcMNPV/MaviMNPV-hybrid genes of egt and orf152. The AcMNPV based hybrid baculovirus is therefore useful as a bio-insecticide by its capability of delivering genes of toxic proteins to be expressed in at least two different insect hosts.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: February 23, 2016
    Assignee: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Tzong-Yuan Wu, Mean-Shine Chen, Chao-Yi Teng, Ying-Ju Chen, Chung-Hsiung Wang
  • Hybrid baculovirus having the capability of infecting at least three insect hosts and uses thereof
    Patent number: 9157072
    Abstract: Disclosed herein is an Autographa californica multiple nucleopolyhedrovirus (AcMNPV) based hybrid baculovirus and its uses thereof. The AcMNPV based hybrid baculovirus is capable of infecting different hosts, and comprises Bombyx mori nuclear polyhedrosis virus (BmNPV) genes of lef9, vlf1, p6.9, and vp80; Maruca vitrata multiple nucleopolyhedrovirus (MaviMNPV) genes of lef2, orf1629, and pe38; and AcMNPV/BmNPV/MaviMNPV-hybrid genes of pk1, lef8, DNA pol, GP41, helicase, orf94, VP1054, orf65, lef4, lef5, and orf99. The AcMNPV based hybrid baculovirus is therefore useful as a bio-tool or bio-insecticide for its capability of delivering genes for production or expression of toxic proteins in at least three different insect hosts.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: October 13, 2015
    Assignee: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Tzong-Yuan Wu, Mean-Shine Chen, Chao-Yi Teng, Ying-Ju Chen
  • HYBRID BACULOVIRUS HAVING THE CAPABILITY OF INFECTING AT LEAST THREE INSECT HOSTS AND USES THEREOF
    Publication number: 20150252333
    Abstract: Disclosed herein is an Autographa californica multiple nucleopolyhedrovirus (AcMNPV) based hybrid baculovirus and its uses thereof. The AcMNPV based hybrid baculovirus is capable of infecting different hosts, and comprises Bombyx mori nuclear polyhedrosis virus (BmNPV) genes of lef9, vlf1, p6.9, and vp80; Maruca vitrata multiple nucleopolyhedrovirus (MaviMNPV) genes of lef2, orf1629, and pe38; and AcMNPV/BmNPV/MaviMNPV-hybrid genes of pk1, lef8, DNA pol, GP41, helicase, orf94, VP1054, orf65, lef4, lef5, and orf99. The AcMNPV based hybrid baculovirus is therefore useful as a bio-tool or bio-insecticide for its capability of delivering genes for production or expression of toxic proteins in at least three different insect hosts.
    Type: Application
    Filed: May 15, 2014
    Publication date: September 10, 2015
    Applicant: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Tzong-Yuan Wu, Mean-Shine Chen, Chao-Yi Teng, Ying-Ju Chen
  • HYBRID BACULOVIRUS AND USES THEREOF
    Publication number: 20150252332
    Abstract: Disclosed herein is an Autographa californica multiple nucleopolyhedrovirus (AcMNPV) based hybrid baculovirus and its uses thereof. The AcMNPV based hybrid baculovirus is capable of infecting different hosts, and comprises Maruca vitrata multiple nucleopolyhedrovirus (MaviMNPV) genes of lef1, orf1629, pk1, CDS1, CDS2, and lef2; and AcMNPV/MaviMNPV-hybrid genes of egt and orf152. The AcMNPV based hybrid baculovirus is therefore useful as a bio-insecticide by its capability of delivering genes of toxic proteins to be expressed in at least two different insect hosts.
    Type: Application
    Filed: March 10, 2014
    Publication date: September 10, 2015
    Applicant: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Tzong-Yuan Wu, Mean-Shine Chen, Chao-Yi Teng, Ying-Ju Chen, Chung-Hsiung Wang