Patents by Inventor Meenakshisunderam Sivakumaran

Meenakshisunderam Sivakumaran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of furaca
    Patent number: 6476220
    Abstract: A process is disclosed for the preparation of 7-amino-3-(2-furanylcarbonylthiomethyl)-3-cephem-4-carboxylic acid (also known as Furaca). The process comprises of the steps of reacting 7-aminocephalosporanic acid with a mixture of 2-thiofuric acid and Boron Trifluoride in a solvent and precipitating Furaca as a solid.
    Type: Grant
    Filed: July 9, 2001
    Date of Patent: November 5, 2002
    Assignee: Aurobindo Pharma Limited
    Inventors: Uthira Kumar, Meenakshisunderam Sivakumaran, Vijay Kumar Handa
  • Ceftiofur, its intermediate and a process for the preparation of the same
    Patent number: 6458949
    Abstract: A novel process for the preparation of ceftiofur, a cephalosporin antibiotic useful in the treatment of bovine respiratory disease using a novel bromo or chloro intermediate. the process comprises of the steps of cyclizing a new bromo or chloro intermediate with thiourea in the presence of selected solvents to produce ceftiofur of high purity. A process to prepare such novel bromo and chloro intermediate comprising of the steps of condensing silylated Furaca with 4-(bromo or chloro)-2 methoxyamino-3-oxobutyric acid or its acid halide is also described.
    Type: Grant
    Filed: July 9, 2001
    Date of Patent: October 1, 2002
    Assignee: Aurobindo Pharma Limited
    Inventors: Vijay Kumar Handa, Meenakshisunderam Sivakumaran, Ramesh Dandala, Venkataiah Sunku
  • Cephalosporin compound and a process for its preparation
    Publication number: 20020065412
    Abstract: A process is disclosed for the preparation of 7-amino-3-(2-furanylcarbonylthiomethyl)-3-cephem-4-carboxylic acid of the formula 1
    Type: Application
    Filed: July 9, 2001
    Publication date: May 30, 2002
    Inventors: Uthira Kumar, Meenakshisunderam Sivakumaran, Vijay Kumar Handa
  • Ceftiofur, its intermediate and a process for the preparation of the same
    Publication number: 20020028931
    Abstract: A novel process for the preparation of ceftiofur, a cephalosporin antibiotic useful in the treatment of bovine respiratory disease. The process utilizes a new bromo or chloro intermediate that can be isolated in a pure form by this inventive process subsequently resulting in ceftiofur of high purity. This invention offers a new-to-the-world route to Ceftiofur using novel intermediates.
    Type: Application
    Filed: July 9, 2001
    Publication date: March 7, 2002
    Inventors: Ramesh Dandala, Venkataiah Sunku, Vijay Kumar Handa, Meenakshisunderam Sivakumaran