Patents by Inventor Meera Nanjundan

Meera Nanjundan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treating endometriosis
    Patent number: 10695341
    Abstract: Provided herein are methods of treating and/or preventing endometriosis or symptom thereof, assays for diagnosing/prognosing endometriosis, compositions and formulations for treating and/or preventing endometriosis or symptom thereof, and populations of endometiotic cells, including life-extended populations of cells.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: June 30, 2020
    Assignees: University of South Florida, Ponce Health Sciences University
    Inventors: Meera Nanjundan, Kyle A. Bauckman, Idhaliz Flores
  • Methods of treating ovarian cancer by modulating SnoN
    Patent number: 8211646
    Abstract: Genomic analysis of ovarian cancers demonstrated a regional chromosomal increase in expression and gene duplication. TGF-? stimulation indicated a link between SnoN RNA and TGF-?. In TIOSE, SnoN protein levels were reduced 15 min post TGF-?-stimulation, likely by proteosome-mediated degradation. SnoN inhibition decreased cell growth between 20 and 50% concurrent with increased p21 levels. Stable expression of SnoN led to growth arrest through induction of senescence. Collectively, these results implicate SnoN levels in multiple roles during ovarian carcinogenesis: promoting cellular proliferation in ovarian cancer cells and as a positive mediator of cell cycle arrest and senescence in non-transformed ovarian epithelial cells.
    Type: Grant
    Filed: November 16, 2009
    Date of Patent: July 3, 2012
    Assignee: University of South Florida
    Inventors: Meera Nanjundan, Gordon Mills, Dawn Smith