Patents by Inventor Meg M. Sun
Meg M. Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8859795Abstract: The invention discloses a technology for producing ester of carboxylic acid using cellulosic biomass as starting material. This technology comprises the following key steps: converting all of the organic polymers, including such high molecular-weight polymers as carbohydrate components and lignin, in cellulosic biomass into water soluble, small molecular organics completely in relatively short time under relatively mild conditions; separating the resultant water soluble compounds containing aromatic rings by adjusting the acidity/basicity of the reaction solution or by using adsorption resin; and converting the water soluble compounds containing aromatic rings into ester of carboxylic acid by hydrogenation and esterification in a corresponding alcohol solution.Type: GrantFiled: September 22, 2009Date of Patent: October 14, 2014Assignee: Sun Pharmaceuticals, Inc.Inventors: Zuolin Zhu, Meg M. Sun, Chungao Su, Hongping Ye
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Patent number: 8759596Abstract: A liquid fuel production process from Cellulosic biomass and coal comprises providing a mixture of Cellulosic biomass and coal, subjecting the mixture to gasification to obtain synthesis gas and converting the synthesis gas to a liquid fuel under the presence of catalyst. The catalyst includes molybdenum sulfide, alkali metal compound and a component activating the C—H bond in alkanes product, wherein the alkali metal compound is selected from the group of salts of Li, Na, K, Rb and Cs, the component activating the C—H bond in alkanes product is selected from Mo, V, Os, Re, Ir, Pt, Pd, Co, Rh, Ni and their mixture. Additionally, co-gasification of Cellulosic biomass and coal can reduce the ash fusion temperature of coal.Type: GrantFiled: April 6, 2007Date of Patent: June 24, 2014Assignee: China Fuel (Huaibei) Bioenergy Technology Development Co., LtdInventors: Hongping Yie, Meg M. Sun, Zuolin Zhu
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Patent number: 8618341Abstract: A liquid fuel production process from cellulosic biomass comprises the following steps: (1) providing a mixture of cellulose and water; (2) subjecting the obtained mixture to hydrolysis and catalytic hydrogenation under the presence of acid to obtain mono-sugar alcohol and optional solid material lignin, or subjecting the obtained mixture to hydrolysis to obtain monosaccharide; (3) esterifying the obtained mono-sugar with C2-C5 organic acid to obtain a liquid fuel II, or subjecting the obtained mono-sugar alcohol or monosaccharide to dehydration/hydrogenation to obtain an organic liquid fuel I consisting of alkanes. This process avoids the loss of organic carbon atoms during fermentation, and the sugar derived from cellulosic biomass can be converted to organic carbon in the liquid fuel. The lignin produced by the process can be used for preparing aromatics.Type: GrantFiled: August 3, 2009Date of Patent: December 31, 2013Assignee: China Fuel (Huaibei) Bioenergy Technology Development Co. LtdInventors: Hongping Yie, Meg M. Sun, Zuolin Zhu
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Publication number: 20130123547Abstract: A method of refining cellulosic biomass, including synchronous hydrolyzation of at least 85 wt % organic polymers, based on the total weight of the cellulosic biomass, in the cellulosic biomass into small molecular organic compounds. The synchronous hydrolyzation is catalytic hydrolyzation for which the catalyst used is a substance represented by L-M-S-H or L-M=S, wherein “M” represents metal, carbon or silicon, “S” represents a heteroatom, “L” represents one or more ligands, and “H” represents hydrogen.Type: ApplicationFiled: September 24, 2012Publication date: May 16, 2013Inventors: Zuolin Zhu, Meg M. Sun, Chungao Su, Hongping Ye
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Publication number: 20130092602Abstract: A continuous reaction system is provided, which specifically relates to a continuous reaction system comprising subcritical and/or supercritical liquid as solvents and a reactant as solid. The invention can effectively prevent cavitations in the reaction system effectively, and realize maximum conversion of the solid reactant material.Type: ApplicationFiled: September 24, 2012Publication date: April 18, 2013Inventors: Zuolin Zhu, Meg M. Sun, Chungao Su, Kangfu Gu, Hongmei Zhao, Xuemei Ma, Weiguo Yu, Daochuang Liu, Zuodong Zhu, Hongping Ye
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Patent number: 8329710Abstract: This disclosure is directed to compound having the formula (A) and a method of treatment using the compound. Compared with metformin, the disclosed compound has the same clinic curative effect, such as lowering blood sugar, curing poly-cystic ovary syndrome (PCOS), losing weight and so on, without resulting in the increase of homocysteine concentration, even with a little decrease of homocysteine concentration in some cases.Type: GrantFiled: May 11, 2007Date of Patent: December 11, 2012Assignee: Sino-Us Pficker Pharmaceuticals Co.Inventors: Hongping Yie, Meg M. Sun, Zuolin Zhu
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Publication number: 20120245367Abstract: The invention discloses a technology for producing ester of carboxylic acid using cellulosic biomass as starting material. This technology comprises the following key steps: converting all of the organic polymers, including such high molecular-weight polymers as carbohydrate components and lignin, in cellulosic biomass into water soluble, small molecular organics completely in relatively short time under relatively mild conditions; separating the resultant water soluble compounds containing aromatic rings by adjusting the acidity/basicity of the reaction solution or by using adsorption resin; and converting the water soluble compounds containing aromatic rings into ester of carboxylic acid by hydrogenation and esterification in a corresponding alcohol solution.Type: ApplicationFiled: September 22, 2009Publication date: September 27, 2012Applicants: China Fuel (Huaibei) Bioenergy Technology Development Co., Ltd., SUN PHARMACEUTICALS, INC.Inventors: Zuolin Zhu, Meg M. Sun, Chungao Su, Hongping Ye
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Patent number: 8124139Abstract: The present invention discloses a compound preparation for quickly reducing oxidative stress, which contains small molecules and mineral trace elements that can remove or help removing free radicals, can regulate the function of endocrine and circulatory digestive system, as well as other components that can rebuild inner harmony. The compound preparation is in solid dosage form, preferably effervescent tablet or effervescent granules. The preparative method of the compound preparation is also disclosed. Animal experiment and clinical trial show that the invention has strong effect in reducing oxidative stress and disease prevention.Type: GrantFiled: April 23, 2007Date of Patent: February 28, 2012Assignee: Sino-US Pficker Pharmaceuticals Co., Ltd.Inventors: Hongping Yie, Meg M. Sun, Zuolin Zhu, Wei Sun, Zhongquan Zhao, Jinyuan Wang, Feng Zheng
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Publication number: 20110223643Abstract: A bionic catalyst for hydrolyzing cellulose and hemicellulose and its preparation method. The catalyst comprises double acid radical catalytic portions and cellulose-linking portions, and can be used under room temperature and high temperature. The catalyst can hydrolyze cellulose and hemicellulose simultaneously, while not decompose glucose and xylose, and may be recycled efficiently. The catalyst can be combined with the process in the prior art to produce liquid fuel.Type: ApplicationFiled: November 23, 2007Publication date: September 15, 2011Applicant: China Fuel (Huaibei) Bioenergy Technology DevelopmInventors: Meg M. Sun, Zuolin Zhu, Hongping Yie
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Publication number: 20110180752Abstract: The invention provides a process for direct liquification of cellulosic biomass, which may be used to liquefy all of the organics in cellulosic biomass, including all high molecular polymeric components such as carbohydrates and lignins, into small molecular organics in a short time under mild conditions. In other words, there is provided a technology capable of converting cellulosic biomass into oil. The resultant renewable high-quality oil may be converted into liquid fuels such as gasoline etc., or used as starting materials in chemical engineering industry. The technology for direct liquification of cellulosic biomass as disclosed in the invention is the first one-step process in the world for direct liquification of cellulosic biomass without black tar formation and gasification.Type: ApplicationFiled: July 28, 2008Publication date: July 28, 2011Applicant: SUN PHARMACEUTICALS, INC.Inventors: Zuolin Zhu, Meg M. Sun, Hongping Yie, Chungao Su
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Publication number: 20100186291Abstract: A liquid fuel production process from Cellulosic biomass and coal comprises providing a mixture of Cellulosic biomass and coal, subjecting the mixture to gasification to obtain synthesis gas and converting the synthesis gas to a liquid fuel under the presence of catalyst. The catalyst includes molybdenum sulfide, alkali metal compound and a component activating the C—H bond in alkanes product, wherein the alkali metal compound is selected from the group of salts of Li, Na, K, Rb and Cs, the component activating the C—H bond in alkanes product is selected from Mo, V, Os, Re, Ir, Pt, Pd, Co, Rh, Ni and their mixture. Additionally, co-gasification of Cellulosic biomass and coal can reduce the ash fusion temperature of coal.Type: ApplicationFiled: April 6, 2007Publication date: July 29, 2010Applicant: CHINA FUEL (HUAIBEI) BIOENERGY TECHNOLOGY DEVELOPMENT CO., LTD.Inventors: Hongping Yie, Meg M. Sun, Zuolin Zhu
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Publication number: 20100105691Abstract: The present invention discloses a novel biguanidine compound, i.e. folacin-metformin, and its manufacture with inorganic salt of metformin as raw material. Compared with metformin, the compound has the same clinic curative effect, such as lowering blood sugar, curing poly-cystic ovary syndrome (PCOS), losing weight and so on, without resulting in the increase of homocysteine concentration, even with a little decrease of homocysteine concentration in some cases.Type: ApplicationFiled: May 11, 2007Publication date: April 29, 2010Applicant: Sino-US Pficker Pharmaceuticals Co. Ltd.Inventors: Hongping Yie, Meg M. Sun, Zuolin Zhu
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Publication number: 20100015115Abstract: The present invention discloses a compound preparation for quickly reducing oxidative stress, which contains small molecules and mineral trace elements that can remove or help removing free radicals, can regulate the function of endocrine and circulatory digestive system, as well as other components that can rebuild inner harmony. The compound preparation is in solid dosage form, preferably effervescent tablet or effervescent granules. The preparative method of the compound preparation is also disclosed. Animal experiment and clinical trial show that the invention has strong effect in reducing oxidative stress and disease prevention.Type: ApplicationFiled: April 23, 2007Publication date: January 21, 2010Applicant: Sino-US PFICKER PHARMACEUTICALS LTD.Inventors: Hongping Yie, Meg M. Sun, Zuolin Zhu, Wei Sun, Zhongquan Zhao, Jinyuan Wang, Feng Zheng
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Publication number: 20090326286Abstract: A liquid fuel production process from cellulosic biomass comprises the following steps: (1) providing a mixture of cellulose and water; (2) subjecting the obtained mixture to hydrolysis and catalytic hydrogenation under the presence of acid to obtain mono-sugar alcohol and optional solid material lignin, or subjecting the obtained mixture to hydrolysis to obtain monosaccharide; (3) esterifying the obtained mono-sugar with C2-C5 organic acid to obtain a liquid fuel II, or subjecting the obtained mono-sugar alcohol or monosaccharide to dehydration/hydrogenation to obtain an organic liquid fuel I consisting of alkanes. This process avoids the loss of organic carbon atoms during fermentation, and the sugar derived from cellulosic biomass can be converted to organic carbon in the liquid fuel. The lignin produced by the process can be used for preparing aromatics.Type: ApplicationFiled: August 3, 2009Publication date: December 31, 2009Applicant: China Fuel (Huaibei) Bioenergy Technology Developme Co. LtdInventors: Hongping Yie, Meg M. Sun, Zuolin Zhu
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Publication number: 20090196910Abstract: A preparation of statins for prolonged release. The preparation is a transdermal therapeutic system or hypodermic implantation system. And they overcome the problem of low bioavailability and increase patient compliance. The statins in the invention contain all of statins and responding salts, hydroxyl ester derivatives at 4-position. The invention has many advantages: for example, reduce dosage frequency, remain stable and lasting blood concentration of medicine, further improve the curative effect, provide patients with a convenient and safety means of administration, and obtain an effective period of up to seven days to months by taking medicine once.Type: ApplicationFiled: November 21, 2005Publication date: August 6, 2009Applicant: PFICKER PHARMACEUTICALS LTD.Inventors: Hongping Yie, Zuolin Zhu, Meg M. Sun
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Publication number: 20090043115Abstract: The present invention discloses a process for producing Simvastatin and intermediate thereof. The present invention uses inexpensive and easily available reagents, its condition is mild, and it leaves out the protective and deprotective steps, which are necessary in prior methods. Compared with prior art, the esterifying condition in 8-position is greatly simplified.Type: ApplicationFiled: September 26, 2005Publication date: February 12, 2009Applicant: PFICKER PHARMACEUTICALS LTD.Inventors: Hongping Ye, Meg M. Sun, Zuolin Zhu
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Publication number: 20080268066Abstract: The present invention discloses a composition preparation for preventing and treating diabetes, which mainly contains oral hypoglycemic agents, Vitamin E, chromic pyridine formate, selenium, lutein, folic acid, Vitamin C, alpha_lipoic acid, lycopene, nicotinamide, coenzyme Q10, and vitamin complexes and mineral. The medicament of the invention can decrease oxidative stress in vivo, promote body immunity, repair the critical organs in vivo such as pancreas, by supplying the mineral, vitamins and other substances which are insufficient in the patient suffering from diabetes, to prevent and treat diabetes.Type: ApplicationFiled: September 23, 2005Publication date: October 30, 2008Applicant: PFICKER PHARMACEUTICALS LTD.Inventors: Hongping Yie, Zuolin Zhu, Meg M. Sun
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Publication number: 20080160001Abstract: The present disclosure provides a combined medicament for reducing blood fat with safety and high efficiency, the active ingredients of which include an agent for lowering blood fat such as statins; an agent for protecting and repairing liver such as silymarin; an agent for protecting kidney, heart, blood vessel or muscle such as coenzyme Q10 and various excipients desired for producing medicaments. The present disclosure can safely and reliably lower the concentration of cholesterol in the blood; protect blood vessels of heart and brain and provide them with nutrition; protect and repair other relevant causes of disease which result in the increasing of blood fat; and lower, even eliminate the side effects of the damage of statins on muscle and liver.Type: ApplicationFiled: March 28, 2005Publication date: July 3, 2008Applicant: PFICKER PHARMACEUTICALS LTD.Inventors: Hongping Ye, Zuolin Zhu, Meg M. Sun