Patents by Inventor Megan Alene Foley

Megan Alene Foley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS
    Publication number: 20210198277
    Abstract: The present disclosure relates to amine-substituted aryl or heteroaryl compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., sickle cell anemia) via inhibition of a methyltransferase enzyme selected from EHMT1 and EHMT2, by administering an amine-substituted aryl or heteroaryl compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: November 20, 2020
    Publication date: July 1, 2021
    Inventors: John Emmerson CAMPBELL, Kenneth William DUNCAN, Megan Alene FOLEY, Darren Martin HARVEY, Kevin Wayne KUNTZ, James Edward John MILLS, Michael John MUNCHHOF
  • AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS
    Publication number: 20170355712
    Abstract: The present disclosure relates to amine-substituted aryl or heteroaryl compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., sickle cell anemia) via inhibition of a methyltransferase enzyme selected from EHMT1 and EHMT2, by administering an amine-substituted aryl or heteroaryl compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: May 22, 2017
    Publication date: December 14, 2017
    Inventors: John Emmerson Campbell, Kenneth William Duncan, Megan Alene Foley, Darren Martin Harvey, Kevin Wayne Kuntz, James Edward John Mills, Michael John Munchhof
  • Ring opening of lactones and lactams
    Patent number: 8779198
    Abstract: The present invention provides a novel process for opening a lactone and/or a lactam ring. More particularly, the present invention provides a process that employs a novel catalyst in the opening of a lactone ring and/or a lactam ring. Additionally, the present invention also provides a novel deprotection process of any protecting group present in either the lactone ring-containing and/or lactam ring-containing compound and/or in the ring-opened product thereof.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: July 15, 2014
    Assignees: Novartis AG, Massachusetts Institute of Technology
    Inventors: Megan Alene Foley, Timothy F. Jamison, Oljan Repic
  • RING OPENING OF LACTONES AND LACTAMS
    Publication number: 20120165555
    Abstract: The present invention provides a novel process for opening a lactone and/or a lactam ring. More particularly, the present invention provides a process that employs a novel catalyst in the opening of a lactone ring and/or a lactam ring. Additionally, the present invention also provides a novel deprotection process of any protecting group present in either the lactone ring-containing and/or lactam ring-containing compound and/or in the ring-opened product thereof.
    Type: Application
    Filed: August 11, 2010
    Publication date: June 28, 2012
    Inventors: Megan Alene Foley, Timothy F. Jamison, Oljan Repic