Patents by Inventor Megan BERTRAND

Megan BERTRAND has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF
    Publication number: 20250090540
    Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of PI3K? enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with PI3K? signaling with the compounds and compositions of the disclosure.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 20, 2025
    Inventors: Alessandro BOEZIO, Alexander M. TAYLOR, Hakan GUNAYDIN, Hanmo ZHANG, Kevin David RAYNOR, Kelley C. SHORTSLEEVES, Lucian V. DIPIETRO, Levi Charles Thomas PIERCE, Nicolas PABON, Thomas H. MCLEAN, Fabrizio GIORDANETTO, Yakov PECHERSKY, Qi WANG, Alexandre LARIVEE, Fei CHEN, Gaetan MAERTENS, Johanne OUTIN, Megan BERTRAND-LAPERLE, Mohan PAL, Sampada CHITALE, Michael Paul DENINNO
  • PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF
    Publication number: 20240287058
    Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of PI3K-? enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with PI3K-? signaling with the compounds and compositions of the disclosure.
    Type: Application
    Filed: April 29, 2021
    Publication date: August 29, 2024
    Inventors: Alessandro BOEZIO, Lucian V. DIPIETRO, Cary Griffin FRIDRICH, Hakan GUNAYDIN, Ravi KURUKULASURIYA, André LESCARBEAU, Mary M. MADER, Thomas H. MCLEAN, Levi CharlesThomas PIERCE, Kevin David RAYNOR, Kelley C. SHORTSLEEVES, Yong TANG, Alexander M. TAYLOR, W. Patrick WALTERS, Hanmo ZHANG, Fabrizio GIORDANETTO, Yakov PECHERSKY, Qi WANG, Bren-Jordan ATIENZA, Megan BERTRAND-LAPERLE, Andrew J. BURNIE, Fei CHEN, Sampada CHITALE, Shorena GELOZIA, Jean-Benoit GIGUERE, Elodie LANDAGARAY, Alexandre LARIVEE, Thomas LEPITRE, Gaetan MAERTENS, Johanne OUTIN, Mohan PAL, Claudio STURINO, Kashif TANVEER, Rakesh THORAT, Naresh VEMULA, Elaine B. KRUEGER, Yue PAN, Michael Paul DENINNO, Yves BOUSQUET, Antoine JOBIN-DES LAURIERS, Jessica LEE, Tarek MOHAMED
  • RESPIRATORY SYNCYTIAL VIRUS INHIBITORS
    Publication number: 20190002436
    Abstract: Compounds of Formula (I): (Formula I), wherein Z1 is NR1A, CHR1A, CR1BR1B; one of Z2 and Z3 is CH or CR1A?, the other is N, CH or CR1A?; n is 0, 1 or 2; q is 0, 1 or 2; R1A, R1A?, R1B, R2, and R3 are as defined herein, their use as inhibitors of RSV and related aspects.
    Type: Application
    Filed: July 28, 2016
    Publication date: January 3, 2019
    Inventors: Susana AYESA, Karolina ERSMARK, Gennadiy KALAYANOV, Marie LEIJONMARCK, Lourdes Salvador ODEN, Hans WESTERLIND, Horst WAHLING, Megan BERTRAND, Christian BROCHU, Elise GHIRO, Cyrille KUHN, Claudio STURINO, Johan BYLUND, Fernando SEHGELMEBLE, Stina LUNDGREN
  • Hepatitis C inhibitor compounds
    Patent number: 9340539
    Abstract: A compound of formula (I) useful for the treatment or prevention of hepatitis C viral infection, (Formula (I)) wherein: X1 and X2 are each independently CRB or N; RB is H, (C1-6)alkyl, (C1-6)haloalkyl, halo.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: May 17, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Christian Brochu, Chantal Grand-Maitre, Lee Fader, Cyrille Kuhn, Megan Bertrand-Laperle, Marc Pesant
  • Substituted pyrazolo[3,4-a]carbazoles as hepatitis C inhibitors
    Patent number: 9340548
    Abstract: The invention relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and R4 are defined herein, and their use for the treatment of hepatitis C viral infection.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: May 17, 2016
    Assignee: Boehringer Ingehleim International GmbH
    Inventors: Christian Brochu, Chantal Grand-Maitre, Marc-Andre Joly, Cyrille Kuhn, Megan Bertrand-Laperle, Marc Pesant
  • HEPATITIS C INHIBITOR COMPOUNDS
    Publication number: 20150291592
    Abstract: Compounds of Formula (I) wherein n, X1, X2, R1, R2, Y1, Y2 and RA are defined herein, are useful for the treatment of hepatitis C viral infection.
    Type: Application
    Filed: August 22, 2012
    Publication date: October 15, 2015
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Christian Brochu, Chantal Grand-Maitre, Marc-Andre Joly, Cyrille Kuhn, Megan Bertrand-Laperle, Marc Pesant
  • HEPATITIS C INHIBITOR COMPOUNDS
    Publication number: 20140343077
    Abstract: A compound of formula (I) useful for the treatment or prevention of hepatitis C viral infection, (Formula (I)) wherein: X1 and X2 are each independently CRB or N; RB is H, (C1-6)alkyl, (C1-6)haloalkyl, halo.
    Type: Application
    Filed: August 22, 2012
    Publication date: November 20, 2014
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Christian Brochu, Chantal Grand-Maitre, Lee Fader, Cyrille Kuhn, Megan Bertrand-Laperle, Marc Pesant
  • VIRAL POLYMERASE INHIBITORS
    Publication number: 20110230465
    Abstract: Compounds of formula I: wherein X, R2, R3, R5 and R6 are defined herein, are useful as inhibitors of the hepatitis C virus NS5B polymerase.
    Type: Application
    Filed: September 16, 2010
    Publication date: September 22, 2011
    Applicant: BOEHRINGER INGLEHEIM INTERNATIONAL GMBH
    Inventors: Timothy STAMMERS, Xavier BARBEAU, Pierre BEAULIEU, Megan BERTRAND-LAPERLE, Christian BROCHU, Paul J. EDWARDS, Pasquale FORGIONE, Cédrickx GODBOUT, Oliver HUCKE, Marc-André JOLY, Serge LANDRY, Olivier LEPAGE, Julie NAUD, Marc PESANT, Martin POIRIER, Maude POIRIER, Bounkham THAVONEKHAM