Patents by Inventor Megan DACEK

Megan DACEK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C825 EXPRESSING IMMUNE CELLS AND DIAGNOSTIC USES THEREOF
    Publication number: 20230348853
    Abstract: Provided herein are compositions comprising engineered immune cells that express a tumor antigen-targeted chimeric antigen receptor and an anti-DOTA C825 antigen binding fragment. The engineered immune cells of the present technology are configured to bind to DOTA haptens that may be complexed with a diagnostic radiopharmaceutical (e.g., 111In). Also disclosed herein are methods for determining the in vivo biodistribution, viability, and expansion of the engineered immune cells described herein.
    Type: Application
    Filed: June 28, 2021
    Publication date: November 2, 2023
    Inventors: Steven Larson, Darren Veach, Sarah Cheal, Ouathek Ouerfelli, Guangbin Yang, Simone Krebs, Megan Dacek, David Scheinberg, Nai-Kong Cheung, Brian Santich
  • SYSTEMS FOR IN VIVO MONITORING OF IMMUNE CELLS IN PATIENTS UNDERGOING CELLULAR IMMUNOTHERAPY
    Publication number: 20230346988
    Abstract: The present disclosure provides kits and methods for tracking or monitoring in vivo biodistribution, viability, and/or expansion of immune cells in a cancer patient undergoing cellular immunotherapy.
    Type: Application
    Filed: June 28, 2021
    Publication date: November 2, 2023
    Inventors: Steven Larson, Darren Veach, Sarah Cheal, Ouathek Ouerfelli, Guangbin Yang, Nai-Kong Cheung, Brian Santich, Simone Krebs, Megan Dacek, David Scheinberg
  • COMPOSITIONS AND METHODS FOR ADOPTIVE CELL THERAPY FOR CANCER
    Publication number: 20210393692
    Abstract: Provided herein are compositions and methods for adoptive cell therapy comprising engineered immune cells that express a tumor antigen-targeted chimeric antigen receptor and a SIRP? polypeptide.
    Type: Application
    Filed: November 12, 2019
    Publication date: December 23, 2021
    Inventors: David A. SCHEINBERG, Thomas GARDNER, Megan DACEK