Patents by Inventor Megan LIGHTFOOT

Megan LIGHTFOOT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED 1,3-PHENYL HETEROARYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE
    Publication number: 20220306617
    Abstract: The invention relates to heterocyclic compounds of the formula (I) in which all of the variables are as defined in the specification; capable of modulating the ctivity of TMEM16a. The invention further provides a method for manufacturing compounds of the invention, and its therapeutic uses. The invention further provides methods to their preparation, to their medical use, in particular to their use in the treatment and management of diseases or disorders including COPD, bronchiectasis, asthma, cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, cystic fibrosis, primary ciliary dyskinesia, respiratory tract infections (acute and chronic; viral and bacterial), lung carcinoma.
    Type: Application
    Filed: August 24, 2020
    Publication date: September 29, 2022
    Inventors: Claire ADCOCK, Jake AXFORD, Ying HOU, Hyungchul KIM, Yiping SHEN, Nichola SMITH, Catherine Fooks SOLOVAY, Moo Je SUNG, Megan LIGHTFOOT, Alessandro MAZZACANI, Emily STANLEY, Lewis WHITEHEAD