Patents by Inventor Megan S. McAfee

Megan S. McAfee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High affinity merkel cell polyomavirus T antigen-specific TCRS and uses thereof
    Patent number: 11534461
    Abstract: The present disclosure provides binding proteins and TCRs with high affinity and specificity against Merkel cell polyomavirus T antigen epitopes or peptides, T cells expressing such high affinity Merkel cell polyomavirus T antigen specific TCRs, nucleic acids encoding the same, and compositions for use in treating Merkel cell carcinoma.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: December 27, 2022
    Assignees: FRED HUTCHINSON CANCER CENTER, UNIVERSITY OF WASHINGTON
    Inventors: Aude G. Chapuis, Paul T. Nghiem, Megan S. McAfee, Natalie J. Miller, Kelly Garneski Paulson, David Martin Koelle, Thomas M. Schmitt, Candice Church
  • HIGH AFFINITY MERKEL CELL POLYOMAVIRUS T ANTIGEN-SPECIFIC TCRS AND USES THEREOF
    Publication number: 20200030378
    Abstract: The present disclosure provides binding proteins and TCRs with high affinity and specificity against Merkel cell Poly-omavirus T antigen epitopes or peptides, T cells expressing such high affinity Merkel cell polyomavirus T antigen specific TCRs, nucleic acids encoding the same, and compositions for use in treating Merkel cell carcinoma.
    Type: Application
    Filed: November 14, 2017
    Publication date: January 30, 2020
    Inventors: Aude G. Chapuis, Paul T. Nghiem, Megan S. McAfee, Natalie J. Miller, Kelly Garneski Paulson, David Martin Koelle, Thomas M. Schmitt, Candice Church