Patents by Inventor Megha Cila

Megha Cila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleotide cleavable linkers and uses thereof
    Patent number: 11970735
    Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: April 30, 2024
    Assignee: Singular Genomics Systems, Inc.
    Inventors: Ronald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez
  • Nucleotide analogues
    Patent number: 11958877
    Abstract: Disclosed herein, interalia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
    Type: Grant
    Filed: March 6, 2023
    Date of Patent: April 16, 2024
    Assignee: Singular Genomics Systems, Inc.
    Inventors: Ronald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez, Abrehet Abdu, Eli N. Glezer
  • Cleavable disulfide linkers and uses thereof
    Patent number: 11946103
    Abstract: Disclosed herein, inter alia, are methods and cleavable compounds that minimize byproduct formation following cleavage.
    Type: Grant
    Filed: August 14, 2023
    Date of Patent: April 2, 2024
    Assignee: Singular Genomics Systems, Inc.
    Inventors: Ronald Graham, Megha Cila
  • Nucleotide analogues
    Patent number: 11878993
    Abstract: Disclosed herein, interalia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
    Type: Grant
    Filed: April 4, 2023
    Date of Patent: January 23, 2024
    Assignee: Singular Genomics Systems, Inc.
    Inventors: Ronald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez, Abrehet Abdu, Eli N. Glezer
  • CLEAVABLE DISULFIDE LINKERS AND USES THEREOF
    Publication number: 20230407389
    Abstract: Disclosed herein, inter alia, are methods and cleavable compounds that minimize byproduct formation following cleavage.
    Type: Application
    Filed: August 14, 2023
    Publication date: December 21, 2023
    Inventors: Ronald Graham, Megha Cila
  • NUCLEOTIDE ANALOGUES
    Publication number: 20230257414
    Abstract: Disclosed herein, interalia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
    Type: Application
    Filed: April 4, 2023
    Publication date: August 17, 2023
    Inventors: Ronald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez, Abrehet Abdu, Eli N. Glezer
  • NUCLEOTIDE ANALOGUES
    Publication number: 20230203083
    Abstract: Disclosed herein, interalia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
    Type: Application
    Filed: March 6, 2023
    Publication date: June 29, 2023
    Inventors: Ronald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez, Abrehet Abdu, Eli N. Glezer
  • NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF
    Publication number: 20230160001
    Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.
    Type: Application
    Filed: May 6, 2021
    Publication date: May 25, 2023
    Inventors: Ada Tong, Ronald Graham, Megha Cila, Eli N. Glezer, Zachary Terranova
  • SILICON CONTAINING DETECTABLE COMPOUNDS AND USES THEREOF
    Publication number: 20230101281
    Abstract: Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof. In an aspect is provided a monovalent nucleotide or monovalent nucleoside covalently bound to a monovalent form of a compound described herein (e.g., wherein the R13 moiety of a compound described herein has reacted with a bioconjugate reactive group to form a bioconjugate linker thereby covalently bonding the monovalent compound to the monovalent nucleotide or monovalent nucleoside).
    Type: Application
    Filed: August 5, 2022
    Publication date: March 30, 2023
    Inventors: Megha Cila, Ronald Graham, Rodrigo Rodriguez
  • NUCLEOTIDE ANALOGUES
    Publication number: 20230028359
    Abstract: Disclosed herein, interalia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
    Type: Application
    Filed: October 24, 2019
    Publication date: January 26, 2023
    Inventors: Ronald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez, Abrehet Abdu, Eli N. Glezer
  • Silicon containing detectable compounds and uses thereof
    Patent number: 11535754
    Abstract: Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof. In an aspect is provided a monovalent nucleotide or monovalent nucleoside covalently bound to a monovalent form of a compound described herein (e.g., wherein the R13 moiety of a compound described herein has reacted with a bioconjugate reactive group to form a bioconjugate linker thereby covalently bonding the monovalent compound to the monovalent nucleotide or monovalent nucleoside).
    Type: Grant
    Filed: May 5, 2022
    Date of Patent: December 27, 2022
    Assignee: Singular Genomics Systems, Inc.
    Inventors: Megha Cila, Ronald Graham, Rodrigo Rodriguez
  • NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF
    Publication number: 20220332752
    Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.
    Type: Application
    Filed: January 7, 2020
    Publication date: October 20, 2022
    Applicant: Singular Genomics Systems, Inc.
    Inventors: Ronald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez
  • SILICON CONTAINING DETECTABLE COMPOUNDS AND USES THEREOF
    Publication number: 20220267603
    Abstract: Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof. In an aspect is provided a monovalent nucleotide or monovalent nucleoside covalently bound to a monovalent form of a compound described herein (e.g., wherein the R13 moiety of a compound described herein has reacted with a bioconjugate reactive group to form a bioconjugate linker thereby covalently bonding the monovalent compound to the monovalent nucleotide or monovalent nucleoside).
    Type: Application
    Filed: May 5, 2022
    Publication date: August 25, 2022
    Inventors: Megha Cila, Ronald Graham, Rodrigo Rodriguez
  • NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF
    Publication number: 20220127299
    Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.
    Type: Application
    Filed: January 7, 2020
    Publication date: April 28, 2022
    Applicant: LG Electronics Inc.
    Inventors: Ronald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez
  • Nucleotide cleavable linkers and uses thereof
    Patent number: 10822653
    Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: November 3, 2020
    Assignee: SINGULAR GENOMICS SYSTEMS, INC.
    Inventors: Ronald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez
  • NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF
    Publication number: 20200340051
    Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.
    Type: Application
    Filed: January 7, 2020
    Publication date: October 29, 2020
    Inventors: Ronald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez
  • Nucleotide analogues
    Patent number: 10738072
    Abstract: Disclosed herein, inter alia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: August 11, 2020
    Assignee: SINGULAR GENOMICS SYSTEMS, INC.
    Inventors: Ronald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez, Abrehet Abdu, Eli N. Glezer