Patents by Inventor Meghan DEWITT

Meghan DEWITT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing recombinant alkaline phosphatase
    Patent number: 11913039
    Abstract: A method of producing recombinant alkaline phosphatase comprising control of production parameters, particularly harvest clarified culture fluid (HCCF) and filtration pool (UFDF), to provide a defined total sialic acid content.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: February 27, 2024
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: Rahul Godawat, Meghan Dewitt, Siguang Sui, Saravanamoorthy Rajendran
  • METHOD OF CONTROLLING TOTAL SIALIC ACID CONTENT (TSAC) DURING MANUFACTURING OF ALKALINE PHOSPHATASE
    Publication number: 20240052327
    Abstract: Featured are methods of manufacturing recombinant alkaline phosphatases, such as asfotase alfa, that provide more precise quality control over total sialic acid content (TSAC) concentration in the final product by measuring TSAC concentration during fermentation and adjusting downstream production steps in response.
    Type: Application
    Filed: October 21, 2021
    Publication date: February 15, 2024
    Applicant: Alexion Pharmaceuticals, Inc.
    Inventors: Meghan DeWitt, Siguang Sui, Rahul Godawat, Sarah Berendes
  • MANUFACTURING OF GLYCOPROTEINS
    Publication number: 20220154155
    Abstract: A method of producing recombinant alkaline phosphatase comprising control of production parameters, particularly harvest clarified culture fluid (HCCF) and filtration pool (UFDF), to provide a defined total sialic acid content.
    Type: Application
    Filed: January 24, 2022
    Publication date: May 19, 2022
    Inventors: Rahul GODAWAT, Meghan DEWITT, Siguang SUI, Saravanamoorthy RAJENDRAN
  • MANUFACTURING OF GLYCOPROTEINS
    Publication number: 20210317425
    Abstract: A method of producing recombinant alkaline phosphatase comprising control of production parameters, particularly harvest clarified culture fluid (HCCF) and filtration pool (UFDF), to provide a defined total sialic acid content.
    Type: Application
    Filed: March 13, 2019
    Publication date: October 14, 2021
    Inventors: Rahul GODAWAT, Meghan DEWITT, Siguang SUI, Saravanamoorthy RAJENDRAN