Patents by Inventor Megumi Kumemura
Megumi Kumemura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9951360Abstract: An object of the present invention is to provide a fermented product containing equol-producing microorganisms in the state of living cells by which equol production ability is maintained. When producing a fermented material by using an equol-producing microorganism, with soybean powder or soybean milk as raw materials, (1) preparing a mother starter by fermentation under anaerobic conditions by using an equol-producing microorganism in the presence of a daidzein species at pH 5.0 or higher, (2) preparing a bulk starter by fermentation under anaerobic conditions by using said mother starter in the presence of a daidzein species at pH 5.0 or higher, and (3) preparing a fermented material by fermentation by using said bulk starter in a medium containing soybean powder or soybean milk, enables production of a fermented material containing microorganisms in the state of living cells in which the equol production ability is maintained.Type: GrantFiled: June 30, 2015Date of Patent: April 24, 2018Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Yoshikazu Isono, Hisako Mori, Tomomi Ueno, Rieko Endo, Megumi Kumemura, Yasuhiro Abiru, Shigeto Uchiyama
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Publication number: 20150299748Abstract: An object of the present invention is to provide a fermented product containing equol-producing microorganisms in the state of living cells by which equol production ability is maintained. When producing a fermented material by using an equol-producing microorganism, with soybean powder or soybean milk as raw materials, (1) preparing a mother starter by fermentation under anaerobic conditions by using an equol-producing microorganism in the presence of a daidzein species at pH 5.0 or higher, (2) preparing a bulk starter by fermentation under anaerobic conditions by using said mother starter in the presence of a daidzein species at pH 5.0 or higher, and (3) preparing a fermented material by fermentation by using said bulk starter in a medium containing soybean powder or soybean milk, enables production of a fermented material containing microorganisms in the state of living cells in which the equol production ability is maintained.Type: ApplicationFiled: June 30, 2015Publication date: October 22, 2015Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Yoshikazu ISONO, Hisako MORI, Tomomi UENO, Rieko ENDO, Megumi KUMEMURA, Yasuhiro ABIRU, Shigeto UCHIYAMA
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Patent number: 9101159Abstract: An object of the present invention is to provide a fermented product containing equol-producing microorganisms in the state of living cells by which equol production ability is maintained. When producing a fermented material by using an equol-producing microorganism, with soybean powder or soybean milk as raw materials, (1) preparing a mother starter by fermentation under anaerobic conditions by using an equol-producing microorganism in the presence of a daidzein species at pH 5.0 or higher, (2) preparing a bulk starter by fermentation under anaerobic conditions by using said mother starter in the presence of a daidzein species at pH 5.0 or higher, and (3) preparing a fermented material by fermentation by using said bulk starter in a medium containing soybean powder or soybean milk, enables production of a fermented material containing microorganisms in the state of living cells in which the equol production ability is maintained.Type: GrantFiled: September 18, 2009Date of Patent: August 11, 2015Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Yoshikazu Isono, Hisako Mori, Tomomi Ueno, Rieko Endo, Megumi Kumemura, Yasuhiro Abiru, Shigeto Uchiyama
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Publication number: 20110189134Abstract: An object of the present invention is to provide a fermented product containing equol-producing microorganisms in the state of living cells by which equol production ability is maintained. When producing a fermented material by using an equol-producing microorganism, with soybean powder or soybean milk as raw materials, (1) preparing a mother starter by fermentation under anaerobic conditions by using an equol-producing microorganism in the presence of a daidzein species at pH 5.0 or higher, (2) preparing a bulk starter by fermentation under anaerobic conditions by using said mother starter in the presence of a daidzein species at pH 5.0 or higher, and (3) preparing a fermented material by fermentation by using said bulk starter in a medium containing soybean powder or soybean milk, enables production of a fermented material containing microorganisms in the state of living cells in which the equol production ability is maintained.Type: ApplicationFiled: September 18, 2009Publication date: August 4, 2011Applicants: OTSUKA PHARMACEUTICAL CO., LTD., OTSUKA FOODS CO., LTD.Inventors: Yoshikazu Isono, Hisako Mori, Tomomi Ueno, Rieko Endo, Megumi Kumemura, Yasuhiro Abiru, Shigeto Uchiyama
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Patent number: 7939060Abstract: This invention provides a composition comprising a daidzein-containing substrate and a strain of micro-organism capable of metabolizing daidzein to equol as essential ingredients. This composition is effective in the prevention and alleviation of unidentified clinical syndrome inclusive of menopausal syndrome in middle-aged to elderly women for which no effective means of prevention or alleviation has heretofore been available.Type: GrantFiled: January 9, 2008Date of Patent: May 10, 2011Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Shigeto Uchiyama, Tomomi Ueno, Megumi Kumemura, Kiyoko Imaizumi, Kyosuke Masaki, Seiichi Shimizu
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Publication number: 20080131412Abstract: This invention provides a composition comprising a daidzein-containing substrate and a strain of micro-organism capable of metabolizing daidzein to equol as essential ingredients. This composition is effective in the prevention and alleviation of unidentified clinical syndrome inclusive of menopausal syndrome in middle-aged to elderly women for which no effective means of prevention or alleviation has heretofore been available.Type: ApplicationFiled: January 9, 2008Publication date: June 5, 2008Inventors: Shigeto Uchiyama, Tomomi Ueno, Megumi Kumemura, Kiyoko Imaizumi, Kyosuke Masaki, Seiichi Shimizu
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Patent number: 7345089Abstract: This invention provides a composition comprising a daidzein-containing substrate and a strain of micro-organism capable of metabolizing daidzein to equol as essential ingredients. This composition is effective in the prevention and alleviation of unidentified clinical syndrome inclusive of menopausal syndrome in middle-aged to elderly women for which no effective means of prevention or alleviation has heretofore been available.Type: GrantFiled: January 8, 2004Date of Patent: March 18, 2008Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Shigeto Uchiyama, Tomomi Ueno, Megumi Kumemura, Kiyoko Imaizumi, Kyosuke Masaki, Seiichi Shimizu
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Publication number: 20040141954Abstract: This invention provides a composition comprising a daidzein-containing substrate and a strain of micro-organism capable of metabolizing daidzein to equol as essential ingredients. This composition is effective in the prevention and alleviation of unidentified clinical syndrome inclusive of menopausal syndrome in middle-aged to elderly women for which no effective means of prevention or alleviation has heretofore been avai lable.Type: ApplicationFiled: January 8, 2004Publication date: July 22, 2004Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Shigeto Uchiyama, Tomomi Ueno, Megumi Kumemura, Kiyoko Imaizumi, Kyosuke Masaki, Seiichi Shimizu
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Patent number: 6716424Abstract: This invention provides a composition comprising a daidzein-containing substrate and a strain of micro-organism capable of metabolizing daidzein to equol as essential ingredients. This composition is effective in the prevention and alleviation of unidentified clinical syndrome inclusive of menopausal syndrome in middle-aged to elderly woman for which no effective means of prevention or alleviation has heretofore been available.Type: GrantFiled: February 8, 2000Date of Patent: April 6, 2004Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Shigeto Uchiyama, Tomomi Ueno, Megumi Kumemura, Kiyoko Imaizumi, Kyosuke Masaki, Seiichi Shimizu
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Patent number: 6656924Abstract: The invention provides an immunopotentiating composition and to a composition accelerating the production of interferon-&ggr;, both comprising lactosuclose as an active ingredient. In particular, the invention provides such compositions in the form of a foodstuff. Oral administration or ingestion of the compositions enhances biophylaxis mechanism (immunological function) in the digestive tract, thus achieving significant treating and preventing effects on intestinal infections and like diseases.Type: GrantFiled: February 26, 2002Date of Patent: December 2, 2003Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Megumi Kumemura, Tatsuya Doi, Takao Saito, Tsuneyuki Noda, Hiroshi Okamatsu
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Patent number: 5455235Abstract: The present invention provides a food composition for inhibiting the formation of an intestinal putrefactive product, containing lactosucrose as an effective component. This food composition is low in calorific value because the lactosucrose is indigestible, and can decrease the amount of an putrefactive product to be generated in intestines. Accordingly, this food composition effectively prevents the outbreak of a variety of cancers for which the putrefactive product might serve as a promoter.Type: GrantFiled: February 9, 1994Date of Patent: October 3, 1995Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Akihisa Takaichi, Toshihiko Okamoto, Yoshihide Azuma, Yoshinari Watanabe, Toshiaki Matsumoto, Katsuya Miyata, Shuichi Sakamoto, Hiroshi Okamatsu, Megumi Kumemura