Patents by Inventor Megumi Ookubo
Megumi Ookubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11161830Abstract: An object of the present invention is to provide a compound or a salt thereof having anti-HBV activity, a pharmaceutical composition, an anti-hepatitis B virus agent, a production inhibitor of DNA of a hepatitis B virus, and a production or secretion inhibitor of a hepatitis B surface antigen. According to the present invention, provided are a compound represented by General Formula [1] or a salt thereof: (in the formula, R1 represents a benzothiazolyl group which may be substituted (in which a carbon atom constituting the 6-membered ring of the benzothiazolyl group of R1 is bonded to the nitrogen atom of the pyridone ring); R2 represents a C2-6 alkenyl group which may be substituted, or the like; and R3 represents a hydrogen atom or the like).Type: GrantFiled: September 26, 2019Date of Patent: November 2, 2021Assignee: FUJIFILM CorporationInventors: Megumi Ookubo, Shinichiro Sekine, Tomoyuki Mashiko, Hyoei Kawai, Hirofumi Fukunaga
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Publication number: 20200017459Abstract: An object of the present invention is to provide a compound or a salt thereof having anti-HBV activity, a pharmaceutical composition, an anti-hepatitis B virus agent, a production inhibitor of DNA of a hepatitis B virus, and a production or secretion inhibitor of a hepatitis B surface antigen. According to the present invention, provided are a compound represented by General Formula [1] or a salt thereof: (in the formula, R1 represents a benzothiazolyl group which may be substituted (in which a carbon atom constituting the 6-membered ring of the benzothiazolyl group of R1 is bonded to the nitrogen atom of the pyridone ring); R2 represents a C2-6 alkenyl group which may be substituted, or the like; and R3 represents a hydrogen atom or the like).Type: ApplicationFiled: September 26, 2019Publication date: January 16, 2020Applicant: FUJIFILM CorporationInventors: Megumi Ookubo, Shinichiro Sekine, Tomoyuki Mashiko, Hyoei Kawai, Hirofumi Fukunaga
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Patent number: 9145415Abstract: The object is to provide an Fms-like tyrosine kinase 3 (FLT3) inhibitor useful as a therapeutic agent for acute myeloid leukemia (AML). A novel nitrogen-containing heterocyclic compound represented by the general formula [1] or a salt thereof is provided. The compound or a salt thereof of the present invention can be used as an active ingredient of a pharmaceutical composition for a treatment of a disease or condition relating to FLT3, such as acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL).Type: GrantFiled: October 16, 2014Date of Patent: September 29, 2015Assignee: FUJIFILM CorporationInventors: Masaru Takasaki, Toshiaki Tsujino, Shintarou Tanabe, Megumi Ookubo, Kimihiko Sato, Atsush Hirai, Daisuke Terada, Shinsuke Inuki, Shinsuke Mizumoto
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Publication number: 20150045339Abstract: The object is to provide an Fms-like tyrosine kinase 3 (FLT3) inhibitor useful as a therapeutic agent for acute myeloid leukemia (AML). A novel nitrogen-containing heterocyclic compound represented by the general formula [1] or a salt thereof is provided. The compound or a salt thereof of the present invention can be used as an active ingredient of a pharmaceutical composition for a treatment of a disease or condition relating to FLT3, such as acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL).Type: ApplicationFiled: October 16, 2014Publication date: February 12, 2015Applicant: FUJIFILM CORPORATIONInventors: Masaru TAKASAKI, Toshiaki TSUJINO, Shintarou TANABE, Megumi OOKUBO, Kimihiko SATO, Atsushi HIRAI, Daisuke TERADA, Shinsuke INUKI, Shinsuke MIZUMOTO
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Patent number: 6702094Abstract: An eccentric crankshaft is connected to a rotary driving device, and a rocking unit is connected to the eccentric crankshaft. Pin roller rolling gear teeth, each having a trochoid tooth-shape, are provided in the rocking unit. When the rocking unit rocks in accordance with eccentric rotation of the eccentric crankshaft, the trochoid shape of the pin roller rolling gear teeth meshes with pin rollers and thus gives a thrust to the pin rollers, thereby driving footsteps.Type: GrantFiled: June 21, 2002Date of Patent: March 9, 2004Assignee: Kabushiki Kaisha ToshibaInventors: Yoshinobu Ishikawa, Megumi Ookubo
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Publication number: 20020179404Abstract: An eccentric crankshaft (8) is connected to a rotary driving device (6), and a rocking unit (10) is connected to the eccentric crankshaft (8). Pin roller rolling gear teeth (11), each having a trochoid tooth-shape, are provided in the rocking unit (10). When the rocking unit (11) rocks in accordance with eccentric rotation of the eccentric crankshaft (8), the trochoid shape of the pin roller rolling gear teeth (11) meshes with pin rollers (5a) and thus gives a thrust to the pin rollers (5a), thereby driving footsteps (2).Type: ApplicationFiled: June 21, 2002Publication date: December 5, 2002Inventors: Yoshinobu Ishikawa, Megumi Ookubo
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Patent number: 6427823Abstract: A conveyor apparatus 20 according to the present invention comprises a tread guide rail 4 which is provided on a structure 120, and a plurality to treads 2 which moves along the tread guide rail 4. The plurality of treads 2 are connected by a chain 5 having pin rollers 5a. An eccentrically rotatable eccentric crank shaft 8 is connected to a rotation drive unit 6. The eccentric crank shaft 8 is connected to an oscillating body 10 which oscillates in accordance with the eccentric rotation of the eccentric crank shaft 8. The oscillating body 10 is provided with pin roller rolling teeth 11 having a trochoid tooth profile for giving thrust to the pin rollers 5a in accordance with the oscillation of the oscillating body 10.Type: GrantFiled: October 15, 2001Date of Patent: August 6, 2002Assignee: Kabushiki Kaisha ToshibaInventors: Yoshinobu Ishikawa, Yoshio Ogimura, Megumi Ookubo
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Patent number: 5353907Abstract: A dual-purpose escalator for a wheelchair including a plurality of steps linked in an endless form and a main-frame having a running path for the steps. The steps include a plurality of specialized steps for loading a wheelchair. The escalator further includes an activating apparatus provided on the running path for causing the specialized steps to alter a configuration thereof to a first state for a wheelchair loading operation mode or to restore the configuration to a second state for normal operation mode. Each of the specialized steps includes a toothed rotor. The activating apparatus includes an engagement member for engaging with the toothed rotor. Each of the toothed rotors is rotated by engaging with the engagement member for causing one of the specialized steps to alter the configuration to the first state when the steps are running in the running path in the wheelchair loading operation mode, respectively.Type: GrantFiled: November 18, 1993Date of Patent: October 11, 1994Assignee: Kabushiki Kaisha ToshibaInventors: Yoshio Ogimura, Megumi Ookubo
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Patent number: 5330042Abstract: An escalator is arranged such that a first special step having a movable footplate capable of rising and falling is combined with a second special step adjacent to the upstream side of the first special step and having a projectable and retractable lift mechanism. The projectable and retractable lift mechanism supports the movable footplate of the first special step in part of a plurality of running steps provided endlessly in a line. When mounting a wheelchair, the movable footplate runs along the inclined path area with the movable footplate supported at the same height as the second special step by operating the lift mechanism in the horizontal path area of the travel path. The movable footplate ensures a rearward footplate dimension sufficient to carry the wheelchair.Type: GrantFiled: January 25, 1993Date of Patent: July 19, 1994Assignee: Kabushiki Kaisha ToshibaInventors: Yoshio Ogimura, Megumi Ookubo