Patents by Inventor Megumu Okada

Megumu Okada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9375434
    Abstract: An antitumor effect potentiator for potentiating one or more other antitumor agents, comprising, as an active ingredient, an imidazooxazine compound represented by Formula (I), or a pharmaceutically acceptable salt thereof, wherein A, B, C, and D represent C—R1a, C—R1b, C—R1c, and C—R1d, respectively, or one or two of A, B, C, and D represent an N atom; at least two of R1a, R1b, R1c, and R1d represent hydrogen, and the other(s) represent(s) halogen; cyano; C1-6 alkyl that may have hydroxyl group(s) as substituent(s); C1-6 alkoxy; carbonyl having, as a substituent, hydroxyl, amino, optionally substituted mono- or di-(C1-6 alkyl)amino, or mono- or di-(C1-6 alkoxy)amino; or an unsaturated heterocyclic group; R2 represents phenyl, pyridyl, or thienyl; R3 represents hydrogen, methyl, ethyl, or cyclopropyl; and R4 represents hydrogen or hydroxy.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: June 28, 2016
    Assignee: Taiho Pharmaceutical Co., Ltd.
    Inventors: Koji Ichikawa, Megumu Okada
  • Patent number: 9289431
    Abstract: An antitumor effect potentiator for potentiating one or more other antitumor agents, comprising, as an active ingredient, an imidazooxazine compound represented by Formula (I), or a pharmaceutically acceptable salt thereof, wherein A, B, C, and D represent C—R1a, C—R1b, C—R1c, and C—R1d, respectively, or one or two of A, B, C, and D represent an N atom; at least two of R1a, R1b, R1c, and R1d represent hydrogen, and the other(s) represent(s) halogen; cyano; C1-6 alkyl that may have hydroxyl group(s) as substituent(s); C1-6 alkoxy; carbonyl having, as a substituent, hydroxyl, amino, optionally substituted mono- or di-(C1-6 alkyl)amino, or mono- or di-(C1-6 alkoxy)amino; or an unsaturated heterocyclic group; R2 represents phenyl, pyridyl, or thienyl; R3 represents hydrogen, methyl, ethyl, or cyclopropyl; and R4 represents hydrogen or hydroxy.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: March 22, 2016
    Assignee: Taiho Pharmaceutical Co., Ltd.
    Inventors: Koji Ichikawa, Megumu Okada
  • Publication number: 20150164909
    Abstract: An antitumor effect potentiator for potentiating one or more other antitumor agents, comprising, as an active ingredient, an imidazooxazine compound represented by Formula (I), or a pharmaceutically acceptable salt thereof, wherein A, B, C, and D represent C—R1a, C—R1b, C—R1c, and C—R1d, respectively, or one or two of A, B, C, and D represent an N atom; at least two of R1a, R1b, R1c, and R1d represent hydrogen, and the other(s) represent(s) halogen; cyano; C1-6 alkyl that may have hydroxyl group(s) as substituent(s); C1-6 alkoxy; carbonyl having, as a substituent, hydroxyl, amino, optionally substituted mono- or di-(C1-6 alkyl)amino, or mono- or di-(C1-6 alkoxy)amino; or an unsaturated heterocyclic group; R2 represents phenyl, pyridyl, or thienyl; R3 represents hydrogen, methyl, ethyl, or cyclopropyl; and R4 represents hydrogen or hydroxy.
    Type: Application
    Filed: July 1, 2013
    Publication date: June 18, 2015
    Applicant: Taiho Pharmaceutical Co., Ltd.
    Inventors: Koji Ichikawa, Megumu Okada
  • Patent number: 7992671
    Abstract: A weight balance of a vehicle body is provided in an all terrain vehicle wherein an engine is supported by a vehicle body frame and an electric power steering device having an actuator unit is provided on a steering shaft. An electric motor is provided in the actuator unit, and heavy objects including a battery and a muffler are disposed on an opposite side to the electric motor in a vehicle width direction with respect to a vehicle body centerline extending in a longitudinal direction of the vehicle and on an opposite side to the electric motor in the longitudinal direction of the vehicle with respect to the engine. To shorten and reduce weight the steering shaft is supported on a vehicle body frame through a radial bearing and ball bearings. Of the plurality of bearings, at least one of the bearings is made self-aligning.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: August 9, 2011
    Assignee: Honda Motor Co., Ltd.
    Inventors: Megumu Okada, Keita Yagi, Kihoko Kaita
  • Patent number: 7967102
    Abstract: A steering shaft support structure for an all terrain vehicle in which both forces of push and pull applied to an EPS unit are reduced when a load is applied to handlebars. The structure includes a steering shaft rotatably supported by a body frame and handlebars attached to the steering shaft. The EPS unit is also supported by the body frame. Two sets of adjustable joints are interposed between the steering shaft and the EPS unit in such a manner that their axes are shiftable. With this, if a load is applied to the handlebars, the adjustable joint associated with the steering shaft follows the inclination of the steering shaft, so that the connection point (swing point) of the adjustable joint associated with the EPS unit does not shift. This reduces both forces of push and pull applied to the EPS unit.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: June 28, 2011
    Assignee: Honda Motor Co., Ltd
    Inventors: Megumu Okada, Keita Yagi, Yotaro Mori, Takeshi Wakabayashi, Kihoko Kaita
  • Patent number: 7878293
    Abstract: To make an electrically-operated power steering unit less susceptible to influence of change in a positional relationship between supporting sections respectively at the two ends of the electrically-operated power steering unit. A gear case included in a electrically-operated power steering unit is attached to the lower section of a vehicle body frame, and the lower end portion of a steering shaft is rotatably supported by a housing annexed to the gear case with an upper bearing interposed in between, in a vehicle in which an input shaft provided to the electrically-operated power steering unit is linked to the lower end portion of the steering shaft, and in which an output shaft provided to the electrically-operated power steering unit is rotatably supported by the lower section of a vehicle body.
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: February 1, 2011
    Assignee: Honda Motor Co., Ltd.
    Inventors: Megumu Okada, Keita Yagi, Yotaro Mori, Takeshi Wakabayashi, Kihoko Kaita, Hiroaki Tomita
  • Patent number: 7775318
    Abstract: A steering shaft joint structure capable of absorbing a rotational phase difference between an input shaft of a power steering unit and an output shaft thereof includes an inner splined portion 53 of a steering joint member 51 joined to an input shaft of a power steering unit and an outer splined portion 55 of the steering joint member 51 joined to a steering shaft. A predetermined rotational phase difference is set between the inner splined portion 53 of the steering joint member 51 and the outer splined portion 55 thereof.
    Type: Grant
    Filed: February 13, 2008
    Date of Patent: August 17, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Megumu Okada, Keita Yagi
  • Publication number: 20100133036
    Abstract: A weight balance of a vehicle body is provided in an all terrain vehicle wherein an engine is supported by a vehicle body frame and an electric power steering device having an actuator unit is provided on a steering shaft. An electric motor is provided in the actuator unit, and heavy objects including a battery and a muffler are disposed on an opposite side to the electric motor in a vehicle width direction with respect to a vehicle body centerline extending in a longitudinal direction of the vehicle and on an opposite side to the electric motor in the longitudinal direction of the vehicle with respect to the engine. To shorten and reduce weight the steering shaft is supported on a vehicle body frame through a radial bearing and ball bearings. Of the plurality of bearings, at least one of the bearings is made self-aligning.
    Type: Application
    Filed: February 1, 2010
    Publication date: June 3, 2010
    Inventors: Megumu Okada, Keita Yagi, Kihoko Kaita
  • Patent number: 7665570
    Abstract: A weight balance of a vehicle body is provided in an all terrain vehicle wherein an engine is supported by a vehicle body frame and an electric power steering device having an actuator unit is provided on a steering shaft. An electric motor is provided in the actuator unit, and heavy objects including a battery and a muffler are disposed on an opposite side to the electric motor in a vehicle width direction with respect to a vehicle body centerline extending in a longitudinal direction of the vehicle and on an opposite side to the electric motor in the longitudinal direction of the vehicle with respect to the engine. To shorten and reduce weight the steering shaft is supported on a vehicle body frame through a radial bearing and ball bearings. Of the plurality of bearings, at least one of the bearings is made self-aligning.
    Type: Grant
    Filed: March 30, 2006
    Date of Patent: February 23, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Megumu Okada, Keita Yagi, Kihoko Kaita
  • Patent number: 7665566
    Abstract: To effectively cool an electric power steering system having an electric motor. A rough terrain vehicle includes an electric motor that is disposed substantially orthogonal to a steering shaft with an engine and an exhaust pipe that are disposed behind the steering shaft and under a seat. A forced air cooling fan is provided for cooling the electric motor. The forced air cooling fan is provided behind the electric motor and in front of the engine or exhaust pipe.
    Type: Grant
    Filed: March 16, 2006
    Date of Patent: February 23, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Megumu Okada, Akio Handa
  • Patent number: 7641022
    Abstract: To provide a motor-driven power steering unit support structure that can absorb mounting errors of a steering shaft. A vehicle includes a steering shaft rotatably supported on a vehicle body frame. A steering bar handle is attached to the upper end of the steering shaft. A motor-driven power steering unit is mounted onto the lower end of the steering shaft, and the vehicle includes at least two front wheels. The motor-driven power steering unit is supported on the vehicle body frame from the vehicle width direction. A front support member and a rear support member for supporting the motor-driven power steering unit are provided in the vehicle body frame on the front and rear sides, with the steering shaft therebetween.
    Type: Grant
    Filed: September 28, 2006
    Date of Patent: January 5, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Megumu Okada, Keita Yagi, Yotaro Mori, Takeshi Wakabayashi, Kihoko Kaita
  • Patent number: 7604084
    Abstract: To provide a layout structure for a motor-driven power steering unit controller configured to take into account the water level at which submergence of the vehicle is expected to occur. In a vehicle including a steering shaft rotatably supported on a vehicle body frame, a steering bar handle attached to the upper end of the steering shaft, a motor-driven power steering unit mounted onto the lower end of the steering shaft, and at least two front wheels, a controller for controlling the motor-driven power steering unit is laid out on the front side relative to the steering shaft and above a horizontal line indicative of the submergence limit of the vehicle.
    Type: Grant
    Filed: September 28, 2006
    Date of Patent: October 20, 2009
    Assignee: Honda Motor Co., Ltd.
    Inventors: Megumu Okada, Keita Yagi, Yotaro Mori, Takeshi Wakabayashi, Kihoko Kaita, Tomokazu Sakamoto
  • Patent number: 7600603
    Abstract: A structure for attaching an electrically-operated power steering apparatus for a vehicle. The structure includes a body frame, more specifically, sub slant frames having respective motor brackets for supporting an actuator unit. The motor brackets have bolts that fasten the actuator unit, and the bolts extend perpendicularly to a steering shaft. With this configuration, the structure is not affected by a manufacturing error of a body frame and other parts of the vehicle. Further, the structure takes account of a direction in which fastening means is tightened.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: October 13, 2009
    Assignee: Honda Motor Co., Ltd.
    Inventors: Megumu Okada, Keita Yagi, Kihoko Kaita
  • Patent number: 7565945
    Abstract: To constrain a load applied to a steering shaft and a power assist unit. In a rough terrain vehicle including a power assist unit including an electrically-driven power steering apparatus provided coaxially with a steering shaft, and an electrically-driven motor provided in the power assist unit arranged so as to be orthogonal to the steering shaft, a rear end portion of the electrically-driven motor is supported by a motor supporting member which is mounted to inclined frames of a vehicle body frame.
    Type: Grant
    Filed: March 17, 2006
    Date of Patent: July 28, 2009
    Assignee: Honda Motor Co., Ltd.
    Inventors: Megumu Okada, Keita Yagi, Kihoko Kaita
  • Publication number: 20080199253
    Abstract: A steering shaft joint structure capable of absorbing a rotational phase difference between an input shaft of a power steering unit and an output shaft thereof includes an inner splined portion 53 of a steering joint member 51 joined to an input shaft of a power steering unit and an outer splined portion 55 of the steering joint member 51 joined to a steering shaft. A predetermined rotational phase difference is set between the inner splined portion 53 of the steering joint member 51 and the outer splined portion 55 thereof.
    Type: Application
    Filed: February 13, 2008
    Publication date: August 21, 2008
    Applicant: HONDA MOTOR CO., LTD
    Inventors: Megumu Okada, Keita Yagi
  • Publication number: 20070096449
    Abstract: A steering shaft support structure for an all terrain vehicle in which both forces of push and pull applied to an EPS unit are reduced when a load is applied to handlebars. The structure includes a steering shaft rotatably supported by a body frame and handlebars attached to the steering shaft. The EPS unit is also supported by the body frame. Two sets of adjustable joints are interposed between the steering shaft and the EPS unit in such a manner that their axes are shiftable. With this, if a load is applied to the handlebars, the adjustable joint associated with the steering shaft follows the inclination of the steering shaft, so that the connection point (swing point) of the adjustable joint associated with the EPS unit does not shift. This reduces both forces of push and pull applied to the EPS unit.
    Type: Application
    Filed: October 27, 2006
    Publication date: May 3, 2007
    Inventors: Megumu Okada, Keita Yagi, Yotaro Mori, Takeshi Wakabayashi, Kihoko Kaita
  • Publication number: 20070095601
    Abstract: To provide a motor-driven power steering unit support structure that can absorb mounting errors of a steering shaft. A vehicle includes a steering shaft rotatably supported on a vehicle body frame. A steering bar handle is attached to the upper end of the steering shaft. A motor-driven power steering unit is mounted onto the lower end of the steering shaft, and the vehicle includes at least two front wheels. The motor-driven power steering unit is supported on the vehicle body frame from the vehicle width direction. A front support member and a rear support member for supporting the motor-driven power steering unit are provided in the vehicle body frame on the front and rear sides, with the steering shaft therebetween.
    Type: Application
    Filed: September 28, 2006
    Publication date: May 3, 2007
    Applicant: HONDA MOTOR CO., LTD.
    Inventors: Megumu Okada, Keita Yagi, Yotaro Mori, Takeshi Wakabayashi, Kihoko Kaita
  • Publication number: 20070074927
    Abstract: To provide a layout structure for a motor-driven power steering unit controller configured to take into account the water level at which submergence of the vehicle is expected to occur. In a vehicle including a steering shaft rotatably supported on a vehicle body frame, a steering bar handle attached to the upper end of the steering shaft, a motor-driven power steering unit mounted onto the lower end of the steering shaft, and at least two front wheels, a controller for controlling the motor-driven power steering unit is laid out on the front side relative to the steering shaft and above a horizontal line indicative of the submergence limit of the vehicle.
    Type: Application
    Filed: September 28, 2006
    Publication date: April 5, 2007
    Applicant: HONDA MOTOR CO., LTD.
    Inventors: Megumu Okada, Keita Yagi, Yotaro Mori, Takeshi Wakabayashi, Kihoko Kaita, Tomokazu Sakamoto
  • Publication number: 20070074928
    Abstract: To make an electrically-operated power steering unit less susceptible to influence of change in a positional relationship between supporting sections respectively at the two ends of the electrically-operated power steering unit. A gear case included in a electrically-operated power steering unit is attached to the lower section of a vehicle body frame, and the lower end portion of a steering shaft is rotatably supported by a housing annexed to the gear case with an upper bearing interposed in between, in a vehicle in which an input shaft provided to the electrically-operated power steering unit is linked to the lower end portion of the steering shaft, and in which an output shaft provided to the electrically-operated power steering unit is rotatably supported by the lower section of a vehicle body.
    Type: Application
    Filed: September 27, 2006
    Publication date: April 5, 2007
    Inventors: Megumu Okada, Keita Yagi, Yotaro Mori, Takeshi Wakabayashi, Kihoko Kaita, Hiroaki Tomita
  • Publication number: 20060219452
    Abstract: A weight balance of a vehicle body is provided in an all terrain vehicle wherein an engine is supported by a vehicle body frame and an electric power steering device having an actuator unit is provided on a steering shaft. An electric motor is provided in the actuator unit, and heavy objects including a battery and a muffler are disposed on an opposite side to the electric motor in a vehicle width direction with respect to a vehicle body centerline extending in a longitudinal direction of the vehicle and on an opposite side to the electric motor in the longitudinal direction of the vehicle with respect to the engine. To shorten and reduce weight the steering shaft is supported on a vehicle body frame through a radial bearing and ball bearings. Of the plurality of bearings, at least one of the bearings is made self-aligning.
    Type: Application
    Filed: March 30, 2006
    Publication date: October 5, 2006
    Inventors: Megumu Okada, Keita Yagi, Kihoko Kaita