Patents by Inventor Mehar Manku

Mehar Manku has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutically acceptable salts of fatty acids
    Patent number: 10544088
    Abstract: The present disclosure provides pharmaceutically acceptable stable salt forms of 15-lipoxygenase products, such as 15-HETrE lysine salt, compositions comprising same and methods of making and using same.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: January 28, 2020
    Assignee: DS Biopharma Limited
    Inventors: Mehar Manku, David Coughlan, Bill Downes
  • Pharmaceutical compositions comprising DGLA and use of same
    Patent number: 10537543
    Abstract: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: January 21, 2020
    Assignee: DS Biopharma Limited
    Inventors: Mehar Manku, John Climax, David Coughlan, James Dunne
  • Methods of treating hypertriglyceridemia
    Patent number: 10537544
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: January 21, 2020
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • STABLE PHARMACEUTICAL COMPOSITION AND METHODS OF USING SAME
    Publication number: 20200000759
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
    Type: Application
    Filed: September 5, 2019
    Publication date: January 2, 2020
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • Stable pharmaceutical composition and methods of using same
    Patent number: 10449172
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: October 22, 2019
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • Compositions and Methods for Lowering Triglycerides Without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy
    Publication number: 20190282533
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
    Type: Application
    Filed: April 15, 2019
    Publication date: September 19, 2019
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • PHARMACEUTICAL COMPOSITIONS COMPRISING DGLA AND USE OF SAME
    Publication number: 20190274989
    Abstract: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
    Type: Application
    Filed: February 19, 2019
    Publication date: September 12, 2019
    Inventors: Mehar Manku, John Climax, David Coughlan, James Dunne
  • COMPOSITIONS AND METHODS FOR LOWERING TRIGLYCERIDES
    Publication number: 20190274991
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
    Type: Application
    Filed: March 26, 2019
    Publication date: September 12, 2019
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • PHARMACEUTICAL COMPOSITIONS COMPRISING DGLA AND USE OF SAME
    Publication number: 20190269639
    Abstract: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
    Type: Application
    Filed: February 19, 2019
    Publication date: September 5, 2019
    Inventors: Mehar Manku, John Climax, David Coughlan, James Dunne
  • METHODS OF TREATING MIXED DYSLIPIDEMIA
    Publication number: 20190240182
    Abstract: The present disclosure relates to, inter alia, methods of treating cardiovascular-related disease.
    Type: Application
    Filed: April 19, 2019
    Publication date: August 8, 2019
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • COMPOSITIONS AND METHODS FOR LOWERING LEVELS OF HIGH-SENSITIVITY (HS-CRP) IN A SUBJECT
    Publication number: 20190240183
    Abstract: The present disclosure provides methods for treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof. In some embodiments, the method comprises lowering high sensitivity CRP (hs-CRP) levels in a subject including, for example, a subject with a HbA1c value of about 5.00% 8.50% or at least about 6.8%.
    Type: Application
    Filed: April 18, 2019
    Publication date: August 8, 2019
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
  • COMPOSITIONS COMPRISING 15-HEPE AND METHODS OF USING THE SAME
    Publication number: 20190216761
    Abstract: The present disclosure relates to the compositions, formulations and methods of treating or preventing diseases mediated by peroxisome proliferator-activated receptors (PPARs) by administration of 15-HEPE.
    Type: Application
    Filed: January 11, 2019
    Publication date: July 18, 2019
    Inventors: John Climax, David Coughlan, Mehar Manku
  • PHARMACEUTICAL COMPOSITION COMPRISING EICOSAPENTAENOIC ACID AND NICOTINIC ACID AND METHODS OF USING SAME
    Publication number: 20190201364
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising eicosapentaenoic acid and/or derivatives thereof and nicotinic acid, to methods of manufacturing such compositions, and to therapeutic methods for treating carious diseases and disorders.
    Type: Application
    Filed: March 12, 2019
    Publication date: July 4, 2019
    Inventor: Mehar Manku
  • METHODS OF TREATING MIXED DYSLIPIDEMIA
    Publication number: 20190183831
    Abstract: The present disclosure relates to, inter alia, methods of treating cardiovascular-related disease.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 20, 2019
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • Compositions and Methods for Lowering Triglycerides without without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy
    Publication number: 20190183829
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
    Type: Application
    Filed: November 21, 2018
    Publication date: June 20, 2019
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • PHARMACEUTICAL COMPOSITIONS COMPRISING DGLA AND USE OF SAME
    Publication number: 20190175534
    Abstract: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and methods of using same to treat a variety of conditions and disorders.
    Type: Application
    Filed: October 11, 2018
    Publication date: June 13, 2019
    Inventors: Mehar Manku, John Climax, David Coughlan, James Dunne
  • COMPOSITIONS AND METHODS FOR LOWERING TRIGLYCERIDES
    Publication number: 20190175538
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
    Type: Application
    Filed: February 12, 2019
    Publication date: June 13, 2019
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • Pharmaceutical composition comprising eicosapentaenoic acid and nicotinic acid and methods of using same
    Patent number: 10314803
    Abstract: The present invention relates to, inter alia, pharmaceutical compositions comprising eicosapentaenoic acid and/or derivatives thereof and nicotinic acid, to methods of manufacturing such compositions, and to therapeutic methods for treating carious diseases and disorders.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: June 11, 2019
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventor: Mehar Manku
  • Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
    Patent number: 10292959
    Abstract: In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: May 21, 2019
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
  • Methods of reducing apolipoprotein C-III
    Patent number: 10265290
    Abstract: In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: April 23, 2019
    Assignee: Amarin Pharmaceuticals Ireland Limited
    Inventors: Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Joseph S. Zakrzewski