Abstract: This disclosure describes systems and methods for providing novel adaptive base flow scheduling during ventilation of a patient to optimize the accuracy of estimated exhaled tidal volume. Further, this disclosure describes systems and methods for providing novel adaptive inspiratory trigger threshold scheduling during the novel adaptive base flow scheduling.

Abstract: A ventilator including a pneumatic system for providing and receiving breathing gas, and a controller operatively coupled with the pneumatic system. The controller is operable to control circulation by the pneumatic system of breathing gas to and from a patient, and to adjust at least one of a volume and pressure of breathing gas delivered to the patient, such adjustment being based upon elastic properties of a component used to fluidly couple the pneumatic system to a patient.

Abstract: This disclosure describes systems and methods for providing novel adaptive base flow scheduling during ventilation of a patient to optimize the accuracy of estimated exhaled tidal volume. Further, this disclosure describes systems and methods for providing novel adaptive inspiratory trigger threshold scheduling during the novel adaptive base flow scheduling.

Abstract: A method for ventilating a patient with a ventilator includes consecutively delivering a plurality of substantially equal volume amounts into a closed ventilator circuit during a ventilator self-test, receiving a pressure measurement for each volume delivery, calculating a change in pressure for each volume delivery, consecutively releasing a plurality of substantially equal volume amounts from the closed ventilator circuit during the ventilator self-test, calculating a change in pressure for each volume release, fitting the calculated change in pressure data for volume delivery and volume release to an inhalation non-linear model equation and an exhalation non-linear model equation, respectively, deriving one or more inhalation tubing compliance compensation coefficients from the inhalation non-linear model equation, and deriving one or more exhalation tubing compliance compensation coefficients from the exhalation non-linear model equation.

Abstract: This disclosure describes systems and methods for detecting and quantifying transmission delays associated with distributed sensing and monitoring functions within a ventilatory system. Specifically, the present methods and systems described herein define an event-based delay detection algorithm for determining transmission delays between distributed signal measurement and processing subsystems and a central platform that receives data from these subsystems. It is important to evaluate and quantify transmission delays because dyssynchrony in data communication may result in the misalignment of visualization and monitoring systems or instability in closed-loop control systems. Generally, embodiments described herein seek to quantify transmission delays by selecting a ventilator-based defining event as a temporal baseline and calculating the delay between the inception of the defining event and the receipt of data regarding the defining event from one or more distributed sensing devices.

Abstract: The systems and methods include providing, displaying, and/or utilizing leak estimation during ventilation of a patient with a ventilator. The systems and methods include providing, displaying, and/or utilizing internal leak estimation, total leak estimation, and/or external leak estimation during ventilation of a patient with a ventilator.

Abstract: This disclosure describes systems and methods for compensating for leakage when during delivery of gas from a medical ventilator in a proportional assist mode to a patient. The technology described herein includes systems and methods to compensate the delivery of PA ventilation for leakage in the patient circuit by using leak-compensated lung flows as well as leak-compensated respiratory mechanics parameters (lung compliance and lung resistance) estimated in a manner that compensates for elastic and inelastic leaks from the ventilation system.

Abstract: This disclosure describes systems and methods for compensating for leakage when during delivery of gas to a patient from a medical ventilator in a pressure regulated volume control (PRVC) ventilation mode. The technology described herein includes systems and methods that compensate the delivery of PRVC ventilation for leakage in the patient circuit by using leak-compensated lung flows as well as respiratory mechanics (lung compliance and lung resistance) estimated in a manner that compensates for elastic and inelastic leaks from the ventilation system.

Abstract: Systems and methods for notifying clinicians of potential patient care risk scenarios and identifying remedial protocols to mitigate the risk. Patient data is downloaded from medical devices associated with the patient, such as, without limitation, a ventilator, bedside monitor, infusion pump, and/or dialysis machine. In addition physician medical orders and treatment notes are received. The patient data, medical orders, and treatment notes are analyzed by a state machine programmed to identify patient risk scenarios based upon known risk factors. Alerts and recommended courses of treatment are generated to enable caregivers to recognize high risk scenarios and to take preventative steps to reduce or avoid suboptimal outcomes. A plurality of state machines may be instantiated, enabling the system to monitor an arbitrary number of patients and treatment protocols.

Abstract: A patient communication system includes a patient communication device, a facility update device, a server, and a portal. The patient communication device is in the bedside environment of a patient within the medical facility. The patient uses the patient communication device to post statuses and send messages to individuals outside of the medical facility to the server. The facility update device provides updates to the server from clinicians and medical devices in the bedside environment of the patient. The server compiles the information from the patient communication device and from the facility update device and automatically posts the status updates to a portal associated with the patient. The portal is accessed by the individuals associated with the patient to receive updates concerning the status of the patient.

Abstract: The present disclosure provides a method of issuing an alert for optimizing interaction between a patient and a ventilatory system. The method includes ventilating a patient using a ventilatory system and retrieving one or more of current ventilatory settings, collected ventilatory data, and patient data. The method also includes detecting corruption of interaction between a patient and the ventilatory system, determining one or more root causes of the corruption, and determining and displaying a recommendation for resolving the corruption based on the one or more root causes.

Abstract: A method for computer assisted holistic patient monitoring includes receiving patient parameters from at least one medical device monitoring a patient, receiving historical patient data from a database, receiving clinician-generated data from a remote device, generating advisory feedback based on the received patient parameters, the received historical data, and the received clinician-generated data, and outputting the advisory feedback for review by a clinician. The method may further include the step of receiving a clinician response to the advisory feedback and storing the clinician response in the database. Additionally, the advisory feedback may be delivered to a second remote device operated by a supervising clinician.

Abstract: This disclosure describes systems and methods for providing novel back-up ventilation that allows the patient to trigger or initiate the delivery of breath. Further, this disclosure describes systems and methods for triggering ventilation when base flow is unknown or undeterminable by the ventilator.

Abstract: Systems and methods are described for application of a transitory corrective modification to a hot-wire anemometer flow voltage and/or calculated flow rate to compensate for transient thermal response of the anemometer during a change in mixture of a mixed gas being measured. According to one embodiment a method of applying the transitory corrective modification is provided. An output signal of an exhalation flow sensor of a medical ventilator is received. The flow sensor includes a hot-wire anemometer. The output signal is indicative of a rate of flow of expired gas by a patient. Transient thermal response of the hot-wire anemometer is compensated for by applying a corrective modification to the output signal or a value based thereon. The corrective modification is based at least in part on a fraction of inspired oxygen (FiO2) being supplied by the medical ventilator to the patient.

Abstract: This disclosure describes systems and methods for providing novel back-up ventilation that allows the patient to trigger or initiate the delivery of breath. Further, this disclosure describes systems and methods for triggering ventilation when base flow is unknown or undeterminable by the ventilator.

Abstract: This disclosure describes systems and methods for providing a transitory ventilation support breath type during ventilation of a patient. The disclosure describes a novel breath type that provides for a beneficial transition between an assist breath type and an effort-based breath type and/or a breath type that is beneficial for weak patients.

Abstract: This disclosure describes systems and methods for detecting disconnect conditions in a ventilator. The disclosure describes a model-based enhancement to conventional disconnect detection. The methods and systems described herein compensate for the additional leakage that occurs due to inelastic and elastic leaks in the ventilation system. One method described includes calculating the actual leakage from the ventilation system including leaks from elastic leakage and inelastic leakage based on measurements of pressure and flow in the ventilation system for a breath and then comparing this leakage to a calculated hypothetical maximum allowable leakage determined based on an operator-selected maximum allowable leakage and the measurements of pressure for the same breath. Disconnection is assumed if the actual leakage is greater than the maximum allowable leakage.

Abstract: Systems and methods are provided for etiologic-based breath simulation and/or ventilator test platforms that provide operator-configurable breathing patterns, patient respiratory muscular effort waveform characteristics and patient parameter values. According to one embodiment, multiple respiratory muscle effort waveform specifications, each of which have associated therewith one or more waveform parameters, are provided for use by a breathing effort generator. The waveform specifications include (i) a specification based upon an empirical model that approximates clinically-observed, patient-generated muscle pressures, (ii) a specification based on configurable etiology-driven templates and/or (iii) a specification based on a configurable piecewise trajectory template. A waveform engine of the breathing effort generator is configured in accordance with a selected waveform specification and corresponding waveform parameter values.

Abstract: This disclosure describes systems and methods for providing an optimized proportional assist breath type during ventilation of a patient. The disclosure describes a novel breath type that delivers a target airway pressure calculated based on a desired patient effort range to a triggering patient.

Abstract: This disclosure describes systems and methods for providing novel back-up ventilation that allows the patient to trigger or initiate the delivery of breath. Further, this disclosure describes systems and methods for triggering ventilation when base flow is unknown or undeterminable by the ventilator.