Abstract: A blood flow regulator for creating a shunt in the heart, comprising; a proximal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the proximal element; a distal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the distal element; and a third element defining a neck section intermediate the proximal and distal elements and forming a cavity having a diameter no greater than a diameter of each of the distal and proximal elements, wherein said distal element comprises at least one loop of a wire extending radially outwardly from a center of the distal element and returning towards said center of said distal element.

Abstract: A blood flow regulator for creating a shunt in the heart, comprising; a proximal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the proximal element; a distal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the distal element; and a third element defining a neck section intermediate the proximal and distal elements and forming a cavity having a diameter no greater than a diameter of each of the distal and proximal elements, wherein said distal element comprises at least one loop of a wire extending radially outwardly from a center of the distal element and returning towards said center of said distal element.

Abstract: The present invention relates to a perfusion balloon catheter that has an expandable (enlargeable) inner lumen (114) with a novel design feature that allows a continuous flow through this enlarged lumen sufficient perfusion to the distal lumen of the blood vessel or air passage concurrent to and independently of balloon (104) inflation or deflation resulting in the prolonged dilatation and avoiding the high risks of blood or air flow stricture during balloon inflation.

Abstract: A system used to entrap clots in arteries, such as cerebral arteries, between the artery wall and an external surface of a stent to provide restoration of blood flow therethrough that includes a stent forming an annular wall that defines a set of openings, and an expansion member extendable through the stent to place a distal portion thereof distal to the stent. The stent is advanced into a clot disposed within a vessel and transitioned to an expanded configuration such that the annular wall engages the clot. The expansion member extends through the stent and is transitioned to an expanded state such that a diameter of the distal portion is greater than a diameter of a proximal portion thereof. The expanded distal portion is sized to fill a portion of the vessel to prevent clot fragments from flowing distal to the expansion member.

Abstract: A device for occluding a patient's left atrial appendage (LAA) device includes a self-expanding closure disc and an anchor. The self-expanding closure disc has an atrial side, an appendage side, and a peripheral edge configured to engage tissue on both an atrial side and an appendage side of an opening between the left atrium and the left atrial appendage. The self-expanding anchor extends from the appendage side of the self-expanding closure disc, and an annular sealing skirt extends about at least a portion of the appendage side of the self-expanding closure disc. the annular sealing skirt is more compliant than the self-expanding closure disc to seal over the left appendage side of the opening after implantation of the device in the LAA.

Abstract: The present invention relates to a medical implantable interatrial septal defect occlusion device to occlude the congenital cardiac malformations such as Atrial Septal Defect (ASD) and Patent Foramen Ovale (PFO) providing hemodynamics between two atria. The occlusion device includes distal and proximal discs having expandable shape memory characteristics, pre-created sealed potential fenestrations which are sealed with biocompatible polymeric patch and sutures to be perforated and used for any possible intervention needed.

Abstract: The invention relates to a clot retrieval and thrombectomy device with adjustable orifice diameter and retrieval length to retrieve embolism from the vascular system, especially pulmonary arteries and venous system, which allows restoring the blood flow to pulmonary vasculature and relieve right heart strain and re-perfusion in occluded veins or arteries with organized thrombus formation. The main objective of the invention is to provide a device that can be used in different vessel dimensions, different types of vessels and situations. The present invention has an adjustable device orifice and retrieval length to overcome the limitations in retrieval of the clots in different vessel dimensions. According to the clot length and volume, the orifice of the braided mesh basket can be adjusted to the vessel diameter. Therefore, the device can be used in every type of vessel having different diameters and in every patient having different conditions.

Abstract: The present invention relates to a perfusion balloon catheter that has an expandable (enlargeable) inner lumen with a novel design feature that allows a continuous flow through this enlarged lumen sufficient perfusion to the distal lumen of the blood vessel or air passage concurrent to and independently of balloon inflation or deflation resulting in the prolonged dilatation and avoiding the high risks of blood or air flow stricture during balloon inflation.

Abstract: A medical occlusion device with proximal and distal portions separated by a connecting member. The proximal and distal portions are shaped to reduce the occurrence of paravalvular leakage by including a peripheral edge that is characterized by rounded corners.

Abstract: A blood flow regulator for creating a shunt in the heart, comprising; a proximal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the proximal element; a distal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the distal element; and a third element defining a neck section intermediate the proximal and distal elements and forming a cavity having a diameter no greater than a diameter of each of the distal and proximal elements, wherein said distal element comprises at least one loop of a wire extending radially outwardly from a center of the distal element and returning towards said center of said distal element.

Abstract: A blood flow regulator for creating a shunt in the heart, comprising; a proximal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the proximal element; a distal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the distal element; and a third element defining a neck section intermediate the proximal and distal elements and forming a cavity having a diameter no greater than a diameter of each of the distal and proximal elements, wherein said distal element comprises at least one loop of a wire extending radially outwardly from a center of the distal element and returning towards said center of said distal element.

Abstract: A medical implantable occlusion device is disclosed comprising a fabric of at least one thread and a structural formation thereof having a collapsed and an expanded shape, the formation comprises a proximal and a distal portion, a longitudinal axis extending between the proximal and distal portion, wherein at least one of the proximal and distal portions comprises a peripheral edge having a first and a second radius of curvature in a direction substantially perpendicular to the longitudinal axis, wherein the first radius of curvature is different from the second radius of curvature.

Abstract: A medical implantable occlusion device is disclosed comprising a fabric of at least one thread and a structural formation thereof having a collapsed and an expanded shape, the formation comprises a proximal and a distal portion, a longitudinal axis extending between the proximal and distal portion, wherein at least one of the proximal and distal portions comprises a peripheral edge having a first and a second radius of curvature in a direction substantially perpendicular to the longitudinal axis, wherein the first radius of curvature is different from the second radius of curvature.

Abstract: A blood flow regulator for creating a shunt in the heart, comprising; a proximal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the proximal element; a distal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the distal element; and a third element defining a neck section intermediate the proximal and distal elements and forming a cavity having a diameter no greater than a diameter of each of the distal and proximal elements, wherein said distal element comprises at least one loop of a wire extending radially outwardly from a center of the distal element and returning towards said center of said distal element.

Abstract: A medical implantable occlusion device (100, 200, 300) is disclosed comprising a braiding (101) of at least one thread, the braiding having an unloaded relaxed state and a stretched state and comprising an expanded diameter portion (102) spanning a distal surface (180) forming the distal end (181) of said device, wherein the braiding is continuous at the distal surface, a tubular member (103) extending along a longitudinal axis (104), the tubular member having a distal portion (105) transitioning into the expanded diameter portion and an opposite proximal portion (106), wherein the tubular member is tapered towards the expanded diameter portion along the longitudinal axis.

Abstract: A medical implantable occlusion device is disclosed comprising a fabric of at least one thread and a structural formation thereof having a collapsed and an expanded shape, the formation comprises a proximal and a distal portion, a longitudinal axis extending between the proximal and distal portion, wherein at least one of the proximal and distal portions comprises a peripheral edge having a first and a second radius of curvature in a direction substantially perpendicular to the longitudinal axis, wherein the first radius of curvature is different from the second radius of curvature.

Abstract: A medical implantable occlusion device (100, 200) is disclosed including a fabric of at least one thread (101) and a structural formation (102) thereof having a collapsed and an expanded shape, the formation including a proximal and a distal portion (103, 104), a longitudinal axis (105) extending between the proximal and distal portion, wherein at least one of the proximal and distal portions including a peripheral edge (107, 108) having a first (109, 109?) and a second (110, 110?) radius of curvature in a direction substantially perpendicular to the longitudinal axis, wherein the first radius of curvature is different from the second radius of curvature.

Abstract: The disclosure relates to a device for occluding an opening in a body and associated methods. The device of this disclosure has the advantage that a second element of the device can be made more flexible than a first element and thereby the device is less prone to increase the rupture size of an opening. In one example, a device (1) for occluding an opening in a body is disclosed, which comprises a first element (2), comprising at least one thread or wire (3), and a second element (6), such as a shaft section, said second element (6) being at least in a longitudinal section tubular or oval and comprising a braided material, said braided material comprising at least one thread or wire (9), and wherein a diameter of said second element (6) is of substantially the same size or smaller than said opening for all longitudinal sections, when said device (1) is in a preset, expanded configuration.

Abstract: A medical implantable occlusion device (100, 200, 300) is disclosed comprising a braiding (101) of at least one thread, the braiding having an unloaded relaxed state and a stretched state and comprising an expanded diameter portion (102) spanning a distal surface (180) forming the distal end (181) of said device, wherein the braiding is continuous at the distal surface, a tubular member (103) extending along a longitudinal axis (104), the tubular member having a distal portion (105) transitioning into the expanded diameter portion and an opposite proximal portion (106), wherein the tubular member is tapered towards the expanded diameter portion along the longitudinal axis.

Abstract: A medical implantable occlusion device (100, 200) is disclosed comprising a fabric of at least one thread (101) and a structural formation (102) thereof having a collapsed and an expanded shape, the formation comprises a proximal and a distal portion (103, 104), a longitudinal axis (105) extending between the proximal and distal portion, wherein at least one of the proximal and distal portions comprises a peripheral edge (107, 108) having a first (109, 109?) and a second (110, 110?) radius of curvature in a direction substantially perpendicular to the longitudinal axis, wherein the first radius of curvature is different from the second radius of curvature.