Abstract: The present invention provides compositions and devices that release (a) a nitric oxide (NO) donor and/or NO, and (b) an agent that aggregates and/or trimerizes the Fas receptor, such as but not limited to a Fas-ligand (FasL). In certain embodiments, the invention includes a stent that elutes (a) a NO donor and/or NO, and (b) FasL. In other embodiments, the invention includes methods of treating a condition, such as intimal hyperplasia, in a subject by administering a stent that releases (a) a NO donor and/or NO, and (b) FasL.

Abstract: A magnetic refrigeration system having a magnetocaloric material for adjusting the temperature of a transfer fluid is disclosed. The magnetic refrigeration system includes tubing filled with the transfer fluid that flows in a first pass through a heat exchanger having a magnetocaloric material that is magnetized by one or more electromagnets and heats the transfer fluid. The magnetocaloric material is magnetized and demagnetized by one or more electromagnets controlled by a timer/controller device. A three-way solenoid valve controls the flow of heated transfer fluid from the heat exchanger and directs the heated transfer fluid to a warm heat exchanger for cooling of the transfer fluid. The cooled transfer fluid is then passed a second time through the heat ex changer in which the magnetocaloric material is demagnetized for further cooling of the cooled transfer fluid.