Abstract: An embolus extractor including elongate shaft having a proximal end and a distal end. The embolus extractor may include first and second struts coupled to the distal end of the shaft. The struts may define a proximally disposed mouth.

Abstract: A variety of devices for use in accessing the subarachnoid space are described. In several embodiments an introducer sheath is disclosed having three main sections, a distal portion, an intermediate portion, and a proximal portion. The distal portion and intermediate portion form a first bend, and the intermediate portion and the proximal portion form a second bend, giving the overall device a general L-shape, S-shape, C-shape, or a three dimensional Z-shape. Apparatuses for attaching an introducer sheath to the skin of a patient are also discussed, as are methods for using, shaping and sizing an introducer sheath.

Abstract: Devices and methods for removing a foreign object from a body lumen are disclosed. An embolectomy device can include a filter basket having a plurality of filter struts forming a cage-like structure that can be expanded to circumferentially surround the incoming foreign object. A support frame including a proximal hoop and one or more rail members may be employed to support the filter basket. The support frame and filter basket can be coupled to a pusher wire that can be used to manipulate the device within the body. In certain embodiments, the filter struts may vary in thickness to impart a desired flexibility characteristic to the device. Methods of manufacturing such devices are also disclosed.

Abstract: A stent assembly comprises an expandable stent having a first stent backbone which extends from the proximal end of the stent to the distal end of the stent. The stent comprises a first stent back bone oriented in a direction which is substantially parallel to a longitudinal axis of the stent, and a plurality of interconnected first stent members and second stent members. Each of the first stent members is oriented in a substantially longitudinal direction in the unexpanded state and the expanded state. Each of the second stent members is oriented in a substantially longitudinal direction in the unexpanded state and oriented in a substantially circumferential direction in the expanded state. The first stent backbone has a greater column strength than that of the plurality of interconnected stent members.

Abstract: An embodiment is a catheter comprising a first elongate shaft having a proximal end, a distal end and a first lumen therethrough, a wire having a proximal end and a distal end at least partially disposed in the first elongate shaft, the distal end extending distally from the first elongate shaft, and a motion control apparatus connected to the proximal end of the wire, further comprising a device attached to the distal end of the wire for changing the shape of an embolus, wherein the device is configured to change the shape of the embolus to unclog a distal catheter lumen.

Abstract: Devices and methods for removing a foreign object from a body lumen are disclosed. An embolectomy device can include a filter basket having a plurality of filter struts forming a cage-like structure that can be expanded to circumferentially surround the incoming foreign object. A support frame including a proximal hoop and one or more rail members may be employed to support the filter basket. The support frame and filter basket can be coupled to a pusher wire that can be used to manipulate the device within the body. In certain embodiments, the filter struts may vary in thickness to impart a desired flexibility characteristic to the device. Methods of manufacturing such devices are also disclosed.

Abstract: An embolus extractor including elongated shaft having a proximal end and a distal end. The embolus extractor may include first and second struts coupled to the distal end of the shaft. The struts may define a proximally disposed mouth.

Abstract: Occlusion-removing devices that include an inflatable balloon for arresting blood flow and a occlusion-shearing element are provided. Also provided are methods of making and using these devices.

Abstract: Occlusion-removing devices that include an inflatable balloon for arresting blood flow and a occlusion-shearing element are provided. Also provided are methods of making and using these devices.

Abstract: An embolus extractor including elongate shaft having a proximal end and a distal end. The embolus extractor may include primary struts coupled to the distal end of the shaft. The struts may define a proximally disposed mouth. Additional secondary struts may be coupled along the elongate shaft to enhance the thrombus containing ability of the embolus extractor.

Abstract: A variety of devices for use in accessing the subarachnoid space are described. In several embodiments an introducer sheath is disclosed having three main sections, a distal portion, an intermediate portion, and a proximal portion. The distal portion and intermediate portion form a first bend, and the intermediate portion and the proximal portion form a second bend, giving the overall device a general L-shape, S-shape, C-shape, or a three dimensional Z-shape. Apparatuses for attaching an introducer sheath to the skin of a patient are also discussed, as are methods for using, shaping and sizing an introducer sheath.

Abstract: Disclosed are methods and devices for navigating a subarachnoid space in a vertebrate organism including percutaneously introducing a device into the spinal subarachnoid space at an entry location. Navigation of the spinal subarachnoid space is disclosed for the purpose of reaching a desired location in the subarachnoid space or the intracranial space, including areas in and around the spinal cord and brain. Once a desired location is reached, methods and devices for cooling or heating the desired location to cause physiologic changes are suggested.

Abstract: An embolus extractor including elongate shaft having a proximal end and a distal end. The embolus extractor may include first and second struts coupled to the distal end of the shaft. The struts may define a proximally disposed mouth.

Abstract: A stent comprises a tubular member having openings therein and having a plurality of interconnected members and one or more frangible restraining members. The frangible restraining members break upon partial expansion of the stent. Thereafter, the stent self-expands.

Abstract: This is an implant for placement in the human body and an assembly for so placing that implant. Most desirably, it is an implant for use in the vasculature of the human body and is used to occlude some space in that vasculature as a portion of a treatment regimen. The implant itself is preferably a component of a deployment device using an electrolytically severable joint. The implant is electrically isolated from the electrolytically severable joint by a highly resistive or insulative layer. Such isolation and minimization of the conductive pathway from the placement apparatus to the body's fluids appears to enhance the susceptibility of the electrolytic joint to quick erosion and detachment of the implant from the deployment media. Although the implant itself is preferably a vaso-occlusive device, it may instead be a stent, a vena cava filter, or other implant which may be installed in this manner.

Abstract: This is an implant for placement in the human body and an assembly for so placing that implant. Most desirably, it is an implant for use in the vasculature of the human body and is used to occlude some space in that vasculature as a portion of a treatment regimen. The implant itself is preferably a component of a deployment device using an electrolytically severable joint. The implant is electrically isolated from the electrolytically severable joint by a highly resistive or insulative layer. Such isolation and minimization of the conductive pathway from the placement apparatus to the body's fluids appears to enhance the susceptibility of the electrolytic joint to quick erosion and detachment of the implant from the deployment media. Although the implant itself is preferably a vaso-occlusive device, it may instead be a stent, a vena cava filter, or other implant which may be installed in this manner.

Abstract: Occlusion-removing devices that include an inflatable balloon for arresting blood flow and a occlusion-shearing element are provided. Also provided are methods of making and using these devices.

Abstract: This is an implant for placement in the human body and an assembly for so placing that implant. Most desirably, it is an implant for use in the vasculature of the human body and is used to occlude some space in that vasculature as a portion of a treatment regimen. The implant itself is preferably a component of a deployment device using an electrolytically severable joint. The implant component is at least partially covered with a highly resistive or insulative covering. The highly resistive or insulative layer or covering appears to enhance the susceptibility of the electrolytic joint to quick erosion and thus detachment of the implant. Although the implant itself is preferably a vaso-occlusive device, it may instead be a stent, a vena cava filter, or other implant which may be installed in this manner. The implant may be independently coated with insulative or resistive material or may be formed using a material with such as tantalum, which forms such an insulator or resistor in situ.

Abstract: An apparatus and method are disclosed for accurately detecting the detachment of both electrically conductive and non-conductive implants which have been introduced to and are intended to remain at a desired therapeutic site. The detachment detection apparatus may include a conductive or an electrically-isolated implant, such as a vasoocclusive coil, connected to a wire by an electrolytically severable joint. The detachment assembly further includes a power supply having a direct current drive circuit for supplying a direct current to the joint, an alternating current drive circuit for independently supplying an alternating current to the joint, and an alternating current monitoring circuit for monitoring an alternating current level of the alternating current supplied to the joint. The detection assembly includes a central processing unit for selecting a first mode and a second mode for determining a detachment threshold level indicating detachment of the implant.

Abstract: This is an artificial occlusion kit for implanting and retaining an artificial occlusion device in a body space adjacent to and extending from a body lumen in a mammal. The includes at least one occlusion device and a retaining device for blocking the migration of the occlusion device out of the occlusion site. The retaining device is radially expandable at a retaining site adjacent the body space to be occluded to a diameter that is sufficient to engage the body lumen wall at the retaining site and form a barrier across the entrance zone of the body space to be occluded. The expanded retaining device also forms a lumen for flow through body lumen at the retaining site. At least one semi-penetrable space may also be provided in the retaining device, allowing introduction of occlusion devices into the body space to be occluded, but preventing subsequent migration of the occlusion devices out of the body space.