Patents by Inventor Mehran M. Khodadoust

Mehran M. Khodadoust has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel italy, LOR-2, strife, trash, BDSF, LRSG, and STMST protein and nucleic acid molecules and uses therefor
    Publication number: 20110020798
    Abstract: Novel ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST proteins, the invention further provides isolated ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST fusion proteins, antigenic peptides and anti-ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST antibodies. The invention also provides ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which an ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: December 18, 2009
    Publication date: January 27, 2011
    Inventors: Douglas A. Holtzman, Sean A. McCarthy, Kyle J. MacBeth, Samantha J. Busfield, Yang Pan, David White, Mehran M. Khodadoust, Wei Gu
  • Novel ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST protein and nucleic acid molecules and uses therefor
    Publication number: 20080248477
    Abstract: Novel ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST proteins, the invention further provides isolated ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST fusion proteins, antigenic peptides and anti-ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST antibodies. The invention also provides ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which an ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: December 11, 2007
    Publication date: October 9, 2008
    Inventors: Douglas A. Holtzman, Sean A. McCarthy, Kyle J. MacBeth, Samantha J. Busfield, Yang Pan, David White, Mehran M. Khodadoust, Wei Gu
  • Novel ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST protein and nucleic acid molecules and uses therefor
    Publication number: 20040176296
    Abstract: Novel ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST proteins, the invention further provides isolated ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST fusion proteins, antigenic peptides and anti-ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST antibodies. The invention also provides ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which an ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: March 22, 2004
    Publication date: September 9, 2004
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Douglas A. Holtzman, Sean A. McCarthy, Kyle J. MacBeth, Samantha J. Busfield, Yang Pan, David White, Mehran M. Khodadoust, Wei Gu
  • FARS1, a human secreted protein and uses thereof
    Publication number: 20030113889
    Abstract: The invention provides isolated nucleic acids molecules, designated FARS1 nucleic acid molecules, which encode novel secreted proteins. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing FARS1 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a FARS1 gene has been introduced or disrupted. The invention still further provides isolated FARS1 proteins, fusion proteins, antigenic peptides and anti-FARS1 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: May 21, 2002
    Publication date: June 19, 2003
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Ruth E. Gimeno, Mehran M. Khodadoust
  • Compositions and methods for the discovery and selection of biological information
    Publication number: 20030003519
    Abstract: Methods and vectors are disclosed for discovering intracellular regulatory pathways utilized by specific stimulatory agents. Suitable stimulatory agents include cytokines, chemical agents, and antibodies. Cell lines and regulatory factors are provided for screening libraries of drug candidates to identify potential therapeutic agents. Methods and compositions are also provided for identifying genes which are necessary for, or capable of, up regulating or down regulating the targeted genomic loci in the selected cells.
    Type: Application
    Filed: October 25, 2001
    Publication date: January 2, 2003
    Inventor: Mehran M. Khodadoust
  • Methods of use of a novel lysyl oxidase-related protein
    Publication number: 20020151007
    Abstract: Novel Lor-2 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length Lor-2 proteins, the invention further provides isolated Lor-2 fusion proteins, antigenic peptides and anti-Lor-2 antibodies. The invention also provides Lor-2 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a Lor-2 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: July 20, 2001
    Publication date: October 17, 2002
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Mehran M. Khodadoust, Kyle J. MacBeth
  • Compositions and methods for the discovery and selection of biological information
    Publication number: 20020076688
    Abstract: Methods and vectors are disclosed for discovering intracellular regulatory pathways utilized by specific stimulatory agents. Suitable stimulatory agents include cytokines, chemical agents and antibodies. Cell lines and regulatory factors are provided for screening libraries of drug candidates to identify potential therapeutic agents. Methods and compositions are also provided for identifying genes which are necessary for or capable of up regulating or down regulating the targeted genomic loci in the selected cells.
    Type: Application
    Filed: July 17, 2001
    Publication date: June 20, 2002
    Inventor: Mehran M. Khodadoust
  • Novel ITALY, Lor-2, STRIFE, TRASH, BDSF, LRSG, and STMST protein and nucleic acid molecules and uses therefor
    Publication number: 20020072089
    Abstract: Novel ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST proteins, the invention further provides isolated ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST fusion proteins, antigenic peptides and anti- ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST antibodies. The invention also provides ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which an ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Application
    Filed: February 13, 2001
    Publication date: June 13, 2002
    Inventors: Douglas A. Holtzman, Sean A. McCarthy, Kyle J. MacBeth, Samantha J. Busfield, Yang Pan, David White, Mehran M. Khodadoust, Wei Gu
  • MSP-18 protein and nucleic acid molecules and uses therefor
    Patent number: 6391602
    Abstract: Novel MSP-18 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length MSP-18 proteins, the invention further provides isolated MSP-18 fusion proteins, antigenic peptides and anti-MSP-18 antibodies. The invention also provides MSP-18 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a MSP-18 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Grant
    Filed: October 31, 2000
    Date of Patent: May 21, 2002
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventor: Mehran M. Khodadoust
  • Methods of use of a novel lysyl oxidase-related protein
    Patent number: 6300092
    Abstract: Novel Lor-2 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length Lor-2 proteins, the invention further provides isolated Lor-2 fusion proteins, antigenic peptides and anti-Lor-2 antibodies. The invention also provides Lor-2 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a Lor-2 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Grant
    Filed: November 23, 1999
    Date of Patent: October 9, 2001
    Assignee: Millennium Pharmaceuticals Inc.
    Inventors: Mehran M. Khodadoust, Kyle J. MacBeth
  • MSP-5 nucleic acid molecules and uses therefor
    Patent number: 6204013
    Abstract: The invention provides isolated nucleic acid molecules, designated MSP-5 nucleic acid molecules, which encode novel myocardium secreted proteins. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MSP-5 nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for producing MSP-5 polypeptides.
    Type: Grant
    Filed: September 29, 1998
    Date of Patent: March 20, 2001
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventor: Mehran M. Khodadoust
  • Thioredoxin family active site molecules and uses therefor
    Patent number: 6174682
    Abstract: Novel thioredoxin family active site molecules, designated MP-4 polypeptides, proteins, and nucleic acid molecules, are disclosed. In addition to isolated, full-length MP-4 proteins, the invention further provides isolated MP-4 fusion proteins, antigenic peptides and anti-MP-4 antibodies. The invention also provides MP-4 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a MP-4 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Grant
    Filed: March 8, 1999
    Date of Patent: January 16, 2001
    Assignee: Millenium Pharmaceuticals, Inc.
    Inventor: Mehran M. Khodadoust
  • MSP-18 protein and nucleic acid molecules and uses therefor
    Patent number: 6140056
    Abstract: Novel MSP-18 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length MSP-18 proteins, the invention further provides isolated MSP-18 fusion proteins, antigenic peptides and anti-MSP-18 antibodies. The invention also provides MSP-18 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a MSP-18 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: October 31, 2000
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventor: Mehran M. Khodadoust