Patents by Inventor Mehran Mojarrad
Mehran Mojarrad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240091440Abstract: A drug delivery device for delivering a medicament includes a housing, a pump, drive component, an inlet fluid path, an outlet fluid path, an inlet pressure sensor, an outlet pressure sensor, and a controller. The pump is coupled with the housing. The drive component is for driving the pump. The inlet fluid path is configured to deliver medicament to the pump. The outlet fluid path is configured to receive medicament from the pump. The inlet pressure sensor is positioned along the inlet fluid path and configured to measure inlet fluid pressure. The outlet pressure sensor is positioned along the outlet fluid path and configured to measure outlet fluid pressure. The controller is workingly coupled with the inlet pressure sensor, the outlet pressure sensor, and the drive component, wherein the controller is configured to adjust at least one parameter of the drive component based on input information received from the inlet pressure sensor and/or the outlet pressure sensor.Type: ApplicationFiled: October 16, 2020Publication date: March 21, 2024Inventors: Scott R. Gibson, Mehran Mojarrad, Paul D. Faucher, Antonio S. Murcia, Alan D. Payne, Sheldon Moberg, Olivia Li
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Publication number: 20240066215Abstract: A drug delivery device for delivering a medicament includes a pump first housing, a pump second housing, an inlet fluid path, and an outlet fluid path. The pump first housing is at least partially supporting and/or surrounding a fluid displacement assembly. The pump second housing is at least partially supporting and/or surrounding a drive component for driving the fluid displacement assembly. The inlet fluid path is configured to deliver medicament to the fluid displacement assembly. The outlet fluid path is configured to receive medicament from the fluid displacement assembly. The pump first housing and the pump second housing are removably coupled with each other.Type: ApplicationFiled: October 14, 2020Publication date: February 29, 2024Inventors: Scott R. Gibson, Mehran Mojarrad, Paul Daniel Faucher, Steven Edward Gorski, Nicholas D.M. Prsha, Eduardo Ho, Rafi Muhammad Sufi
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Patent number: 11890450Abstract: A drug delivery device includes a housing defining a shell and an inner volume, a container, a drive mechanism, a needle assembly, a fluid flow connection, and a backflow prevention mechanism. The container has an inner volume to contain a medicament to be administered to a user. The drive mechanism is at least partially disposed within the housing and exerts a force to urge the medicament out the container. The fluid flow connection is coupled to the container and the needle assembly and allows the medicament to flow from the container to the needle assembly to be administered. The backflow prevention mechanism is associated with at least one of the container, the fluid flow connection, or the needle assembly and includes at least one flow restrictor to restrict a fluid from flowing from the needle assembly to the container.Type: GrantFiled: March 8, 2019Date of Patent: February 6, 2024Assignee: AMGEN INC.Inventors: Lawrence Scott Ring, Tohid Pirbodaghi, Samin Akbari, Daniel Eduardo Groszmann, Mehran Mojarrad, Mark Gordon, Mikhail Tikh, Jimmie L. Ward, Scott R. Gibson, Sheldon B. Moberg, Joshua Tamsky, Paul Faucher, Jeff Lind
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Publication number: 20230347075Abstract: A drug delivery device includes a housing, a container disposed in the housing, a drive mechanism, a needle assembly, a fluid flow path, and a vortex flow adapter. The container contains a medicament which is urged out of the container by the drive mechanism. The needle assembly has a needle and/or a cannula to deliver the medicament from the container. The fluid flow path fluidically connects the container and the needle assembly. The vortex flow adapter is disposed within or defines at least a portion of the fluid flow path, and is adapted to urge the medicament to flow in a vortex pattern.Type: ApplicationFiled: November 17, 2020Publication date: November 2, 2023Inventors: Ali Nekouzadeh, Mehran Mojarrad, Joshua Tamsky, Paul Daniel Faucher, Scott R. Gibson, Kimberly Sepulveda, Sheldon B. Moberg
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Publication number: 20230302264Abstract: A swallowable drug delivery device includes a capsule and a tissue attachment member. The capsule may contain a drug and may be sized to pass through at least a portion of the gastrointestinal tract of a patient. The tissue attachment member may be coupled to the capsule. In an initial state, the tissue attachment member may allow the capsule to pass through the at least a portion of the gastrointestinal tract of the patient. In an activated state, the tissue attachment member is configured to at least selectively attach the capsule to a wall of the gastrointestinal tract of the patient. The tissue attachment member may be configured to change from the initial state to the activated state in response to an in vivo condition associated with a predetermined location in the gastrointestinal tract of the patient.Type: ApplicationFiled: September 2, 2021Publication date: September 28, 2023Inventors: Mehran Mojarrad, Scott R. Gibson, Scott Castanon, Robert Eisele, Dylann Ceriani
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Patent number: 11766519Abstract: A flexible plunger rod, drug delivery mechanism, drug delivery device, and methods are described that utilize the flexible plunger rod perform drug delivery operations. In embodiments, the flexible plunger rod can be stored in a curved configuration to thereby reduce a footprint of the drug delivery mechanism and device.Type: GrantFiled: January 17, 2019Date of Patent: September 26, 2023Assignee: AMGEN INC.Inventors: Sudeshna Dutta Ray, Scott R. Gibson, Daniel Eduardo Groszmann, Mehran Mojarrad, Robert Allen Dees, Jonathan Dean Johnson, Antonio S. Murcia
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Patent number: 11660435Abstract: The devices, assemblies, and methods described herein utilize photoacoustic principals to create a jet of fluid using a ultrasonic resonance member and a pulsed laser light beam. The ultrasonic resonance member is a treated substrate having an liquid interface surface in contact with a fluid. When a pulsed laser light beam is applied to the treated substrate, pressure is generated via induced ultrasonic waves to urge the fluid into a jet stream.Type: GrantFiled: October 5, 2020Date of Patent: May 30, 2023Assignee: AMGEN INC.Inventors: Mehran Mojarrad, Scott R. Gibson, Heejin Lee
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Publication number: 20220401643Abstract: A drug delivery device includes a drug product container, a pressurized vessel, and an urging member. The drug product container can have at least one flexible wall and defining a cavity configured to contain a drug product. The pressurized vessel can contain a gas under pressure. And the urging member is in working connection with the pressurized vessel such that, upon at least partial release of the gas under pressure, the urging member moves from a first portion of the drug product container to a second portion, thereby ejecting at least a portion of the drug product from the drug product container.Type: ApplicationFiled: October 14, 2020Publication date: December 22, 2022Inventors: Scott R. Gibson, Paul D. Faucher, Mehran Mojarrad
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Publication number: 20220387702Abstract: A drug delivery device is provided that includes a housing, a fluid displacement assembly at least partially supported by and/or surrounded by the housing, and a drive component at least partially supported by and/or surrounded by the housing. The fluid displacement assembly includes a ring tube portion. The drive component includes an eccentric component having a contact surface configured to directly or indirectly apply a compression force to a compression patch of the ring tube portion such that when the eccentric component rotates about an axis, the contact surface moves along generally circular path and drives the medicament through the fluid displacement assembly. The compression force between the contact surface and the ring tube portion is preferably substantially constant throughout a complete revolution about the axis by the eccentric component.Type: ApplicationFiled: October 23, 2020Publication date: December 8, 2022Inventors: Scott R. Gibson, Mehran Mojarrad, Paul D. Faucher
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Publication number: 20220331204Abstract: Drug reconstitution systems and related methods are disclosed herein. A drug reconstitution system may include a first component in a first container in a storage state and a second component in a second container in a storage state. The first component may be selected from a group of a drug product, a diluent, a saline solution, and an IV stabilizing solution (“IVSS”). The second component may be selected from a group of the drug product, the diluent, the saline solution, and the IVSS. The first component may be different than the second component. At least one fluid path may be configured to at least selectively fluidly connect the first container and the second container. An urging assembly may be configured to selectively urge at least a portion of the first component from the first container and into contact with the second component.Type: ApplicationFiled: October 16, 2020Publication date: October 20, 2022Inventors: Mehran Mojarrad, Scott R. Gibson, Xiaotong Li
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Publication number: 20220288305Abstract: A drug delivery device includes a housing releasably coupled with a patient, a pressure chamber disposed in the housing and including a vent, a container at least partially disposed in the pressure chamber for storing a drug connectable in fluid communication with a fluid conduit, an activation mechanism, and a relief mechanism. The activation mechanism releases a pressurized drive fluid into the pressure chamber for expelling the drug from the container into the fluid conduit. The relief mechanism is operably coupled to the fluid conduit and is adapted to open the vent to release the drive fluid from the pressure chamber in response to a predetermined condition.Type: ApplicationFiled: July 16, 2020Publication date: September 15, 2022Inventors: Mehran Mojarrad, Ali Nekouzadeh, Scott R. Gibson, Sheldon Moberg, Paul Daniel Faucher
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Publication number: 20220265975Abstract: The devices, assemblies, and methods described herein utilize photoacoustic principals to create a jet of fluid using a ultrasonic resonance member and a pulsed laser light beam. The ultrasonic resonance member is a treated substrate having an liquid interface surface in contact with a fluid. When a pulsed laser light beam is applied to the treated substrate, pressure is generated via induced ultrasonic waves to urge the fluid into a jet stream.Type: ApplicationFiled: October 5, 2020Publication date: August 25, 2022Inventors: Mehran Mojarrad, Scott R. Gibson, Heejin Lee
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Publication number: 20220249778Abstract: A drug delivery device includes a housing releasably coupled with a patient, a container disposed in the housing, a plunger disposed in the container, an activation mechanism, and a seal member. The container includes a wall with an interior surface. The plunger includes an interior surface and is moveably disposed in the container. The interior surfaces of the wall and the plunger define a reservoir adapted to contain a drug. The activation mechanism is adapted to release a drive fluid for moving the plunger through the container to expel the drug therefrom. The seal member is moveably disposed in the container and is adapted to inhibit ingress of the drive fluid into the reservoir.Type: ApplicationFiled: July 16, 2020Publication date: August 11, 2022Inventors: Mehran Mojarrad, Ali Nekouzadeh, Sheldon B. Moberg, Scott R. Gibson, Paul Daniel Faucher
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Patent number: 11305056Abstract: An insertion/retraction mechanism for a drug delivery device is disclosed. The insertion/retraction mechanism includes a retraction hub, an insertion hub, an insertion/retraction mechanism housing, and a dual torsion spring system. The retraction hub includes a first primary rotational stop and a second primary rotational stop extending radially inwardly from an inside surface. The insertion hub is disposed inside the retraction hub and comprises a first complementary rotational stop and a second complementary rotational stop extending radially outwardly from an outside surface.Type: GrantFiled: July 14, 2018Date of Patent: April 19, 2022Assignee: AMGEN INC.Inventors: Mehran Mojarrad, Scott Robert Gibson, Adam Livingston
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Publication number: 20220047808Abstract: Modular fluid path assemblies are provided that include conduit, coupling, and needle portions of a fluid path fluidly coupled to an outlet of a container. The modular fluid path assemblies further include a needle shield having a tip of the needle embedded therein. So configured, in embodiments, the modular fluid path assemblies can be sterilized, a medicament can be filled in the container, and a stopper inserted in the container so that the pre-sterilized and pre-filled modular fluid path assemblies can have a closed container integrity (CCI) seal.Type: ApplicationFiled: June 28, 2021Publication date: February 17, 2022Inventors: Scott Robert GIBSON, Sudeshna DUTTA RAY, Daniel Eduardo GROSZMANN, Mehran MOJARRAD, Nathan Thomas BALCOM, Alejandro CAMPILLO-AGUSTI, Alan D. PAYNE, Lawrence Scott RING
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Publication number: 20210346601Abstract: Systems and methods for interventional dosing based on sensed feedback are disclosed. A system may include one or more reservoirs filled or fillable with, respectively, one or more drug products, an administration member, a fluid delivery system, one or more sensors, and optionally a controller. The administration member may be insertable into a patient and connected or connectable in fluid communication with the one or more reservoirs. The fluid delivery system may be operable to deliver the one or more drug products from the one or more reservoirs to the patient via the administration member. The one or more sensors may be operable to sense one or more biological conditions of the patient, including, but not limited to, a cytokine level and/or a biomarker indicative of cytokine release syndrome. The controller may be configured to control operation of the fluid delivery system based on output from the one or more sensors.Type: ApplicationFiled: September 23, 2019Publication date: November 11, 2021Inventors: Heejin Lee, Scott Robert Gibson, Mehran Mojarrad, Jeffrey Schacherl
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Patent number: 11083840Abstract: Modular fluid path assemblies are provided that include conduit, coupling, and needle portions of a fluid path fluidly coupled to an outlet of a container. The modular fluid path assemblies further include a needle shield having a tip of the needle embedded therein. So configured, in embodiments, the modular fluid path assemblies can be sterilized, a medicament can be filled in the container, and a stopper inserted in the container so that the pre-sterilized and pre-filled modular fluid path assemblies can have a closed container integrity (CCI) seal.Type: GrantFiled: June 1, 2018Date of Patent: August 10, 2021Assignee: AMGEN INC.Inventors: Scott Robert Gibson, Sudeshna Dutta Ray, Daniel Eduardo Groszmann, Mehran Mojarrad, Nathan Thomas Balcom, Alejandro Campillo-Agusti, Alan D. Payne, Lawrence Scott Ring
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Publication number: 20210228811Abstract: Drug delivery devices are described that include an escapement activation assembly. The escapement activation assembly includes a slide having a plurality of pallet engagement portions and a switch engagement portion and a pallet having a plurality of slide engagement portions. A drive is coupled to the pallet to cause the pallet to move relative to the slide to move the plurality of slide engagement portions into and out of engagement with the plurality of pallet engagement portions to allow the slide to move along a path within the drug delivery device. Movement of the slide can cause the switch engagement portion to move out of engagement with an activation trigger of a mechanism of the drug delivery device.Type: ApplicationFiled: September 17, 2019Publication date: July 29, 2021Inventors: Sudeshna Dutta Ray, Scott Robert Gibson, Daniel Eduardo Groszmann, Mehran Mojarrad, Andrew James Carlson, Lee Gordon Macklem, Mikhail Tikh
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Patent number: D963158Type: GrantFiled: October 24, 2019Date of Patent: September 6, 2022Assignee: AMGEN INC.Inventors: Scott R. Gibson, Mehran Mojarrad, Paul Daniel Faucher
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Patent number: D965139Type: GrantFiled: October 24, 2019Date of Patent: September 27, 2022Assignee: AMGEN INC.Inventors: Scott R. Gibson, Mehran Mojarrad, Paul Daniel Faucher