Abstract: A tissue anchor deployment device includes a needle having a slotted portion including a longitudinal slot that runs from a distal end of the needle and a suture having a first coil portion including a plurality of turns that wrap around a first portion of the slotted portion of the needle, a second coil portion including a plurality of turns that wrap around a second portion slotted portion of the needle that is proximal to the first portion of the slotted portion of the needle, and an internal coupling portion that runs within the first coil portion and the second coil portion and couples a distal end of the first coil portion to a proximal end of the second coil portion.

Abstract: Disclosed herein is a bidirectional intravascular cannula, or catheter, that is configured to provide and return blood in a patient bidirectionally. The bidirectional intravascular cannula is configured to reduce or obviate the need for a second cannula, such as currently available unidirectional cannulae, to be placed in a second or opposite direction of flow. Users would include cardiac surgeons, intensivists, vascular surgeons, ER doctors, IR doctors and cardiologist who use peripheral cannulation for ECLS or cardiopulmonary bypass. The cannula allows continued flow to a patient's limb even with the cannula proximally in the vessel. The cannula further allows larger size cannula to be placed without the need for additional distal catheter placement.

Abstract: A tissue anchor deployment device includes a needle having a slotted portion including a longitudinal slot that runs from a distal end of the needle and a suture having a first coil portion including a plurality of turns that wrap around a first portion of the slotted portion of the needle, a second coil portion including a plurality of turns that wrap around a second portion slotted portion of the needle that is proximal to the first portion of the slotted portion of the needle, and an internal coupling portion that runs within the first coil portion and the second coil portion and couples a distal end of the first coil portion to a proximal end of the second coil portion.

Abstract: Disclosed herein is a bidirectional intravascular cannula, or catheter, that is configured to provide and return blood in a patient bidirectionally. The bidirectional intravascular cannula is configured to reduce or obviate the need for a second cannula, such as currently available unidirectional cannulae, to be placed in a second or opposite direction of flow. Users would include cardiac surgeons, intensivists, vascular surgeons, ER doctors, IR doctors and cardiologist who use peripheral cannulation for ECLS or cardiopulmonary bypass. The cannula allows continued flow to a patient's limb even with the cannula proximally in the vessel. The cannula further allows larger size cannula to be placed without the need for additional distal catheter placement.

Abstract: Disclosed herein is a bidirectional intravascular cannula, or catheter, that is configured to provide and return blood in a patient bidirectionally. The bidirectional intravascular cannula is configured to reduce or obviate the need for a second cannula, such as currently available unidirectional cannulae, to be placed in a second or opposite direction of flow. Users would include cardiac surgeons, intensivists, vascular surgeons, ER doctors, IR doctors and cardiologist who use peripheral cannulation for ECLS or cardiopulmonary bypass. The cannula allows continued flow to a patient's limb even with the cannula proximally in the vessel. The cannula further allows larger size cannula to be placed without the need for additional distal catheter placement.

Abstract: A tissue anchor deployment device includes a needle having a slotted portion including a longitudinal slot that runs from a distal end of the needle and a suture having a first coil portion including a plurality of turns that wrap around a first portion of the slotted portion of the needle, a second coil portion including a plurality of turns that wrap around a second portion slotted portion of the needle that is proximal to the first portion of the slotted portion of the needle, and an internal coupling portion that runs within the first coil portion and the second coil portion and couples a distal end of the first coil portion to a proximal end of the second coil portion.

Abstract: Disclosed herein is a guidewire configured for placement of large bore catheters and cannulae inside of a patient's blood vessels without fluoroscopic guidance. The guidewire, in accordance with certain aspects of an embodiment of the invention, comprises sections of varying stiffness throughout optimally fixed length portions of the guidewire that particularly ease placement of such large bore catheters and cannulae in ECMO applications.

Abstract: Methods and devices for repairing a cardiac valve. A minimally invasive procedure includes creating an access in the apex region of the heart through which one or more instruments may be inserted. The device can implant artificial heart valve chordae tendineae into cardiac valve leaflet tissues to restore proper leaflet function and prevent reperfusion. The device punctures the apex of the heart and travels through the ventricle. The tip of the device rests on the defective valve and punctures the valve leaflet. A suture or a suture/guide wire combination is inserted, securing the top of the leaflet to the apex of the heart. A resilient element or shock absorber mechanism adjacent to the outside of the apex of the heart minimizes the linear travel of the device in response to the beating of the heart or opening/closing of the valve.

Abstract: Methods and devices for repairing a cardiac valve. A minimally invasive procedure includes creating an access in the apex region of the heart through which one or more instruments may be inserted. The device can implant artificial heart valve chordae tendineae into cardiac valve leaflet tissues to restore proper leaflet function and prevent reperfusion. The device punctures the apex of the heart and travels through the ventricle. The tip of the device rests on the defective valve and punctures the valve leaflet. A suture or a suture/guide wire combination is inserted, securing the top of the leaflet to the apex of the heart. A resilient element or shock absorber mechanism adjacent to the outside of the apex of the heart minimizes the linear travel of the device in response to the beating of the heart or opening/closing of the valve.

Abstract: Methods and devices for repairing a cardiac valve. A minimally invasive procedure includes creating an access in the apex region of the heart through which one or more instruments may be inserted. The device can implant artificial heart valve chordae tendineae into cardiac valve leaflet tissues to restore proper leaflet function and prevent reperfusion. The device punctures the apex of the heart and travels through the ventricle. The tip of the device rests on the defective valve and punctures the valve leaflet. A suture or a suture/guide wire combination is inserted, securing the top of the leaflet to the apex of the heart. A resilient element or shock absorber mechanism adjacent to the outside of the apex of the heart minimizes the linear travel of the device in response to the beating of the heart or opening/closing of the valve.

Abstract: Methods and devices for repairing a cardiac valve. A minimally invasive procedure includes creating an access in the apex region of the heart through which one or more instruments may be inserted. The device can implant artificial heart valve chordae tendineae into cardiac valve leaflet tissues to restore proper leaflet function and prevent reperfusion. The device punctures the apex of the heart and travels through the ventricle. The tip of the device rests on the defective valve and punctures the valve leaflet. A suture or a suture/guide wire combination is inserted, securing the top of the leaflet to the apex of the heart. A resilient element or shock absorber mechanism adjacent to the outside of the apex of the heart minimizes the linear travel of the device in response to the beating of the heart or opening/closing of the valve.