Patents by Inventor Mehrdad R. Majlessi

Mehrdad R. Majlessi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11976337
    Abstract: This disclosure concerns amplification primers, hybridization assay probes, compositions containing such primers and probes, and associated reagents, kits, and methods, that can be used to analyze samples for the presence of Influenza A virus, Influenza B virus, Respiratory Syncytial Virus A, and/or Respiratory Syncytial Virus B target nucleic acids.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: May 7, 2024
    Assignee: GEN-PROBE INCORPORATED
    Inventors: Matthias Jost, Pamela Douglass, Daniel P. Kolk, Mehrdad R. Majlessi
  • Publication number: 20230203572
    Abstract: The disclosed disclosure is related to methods, compositions, and kits for targeting Adenovirus, Metapneumovirus, and/or Rhinovirus nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers. Kits and methods comprise at least one of these oligomers. Methods include uniplex and multiplex amplification and detection reactions.
    Type: Application
    Filed: December 27, 2022
    Publication date: June 29, 2023
    Inventors: Mehrdad R. MAJLESSI, Ankur SHAH, Amber HILLIUS, Pamela DOUGLASS, Daniel KOLK
  • Publication number: 20230203571
    Abstract: The disclosed disclosure is related to methods, compositions, and kits for targeting Adenovirus, Metapneumovirus, and/or Rhinovirus nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers. Kits and methods comprise at least one of these oligomers. Methods include uniplex and multiplex amplification and detection reactions.
    Type: Application
    Filed: December 27, 2022
    Publication date: June 29, 2023
    Inventors: Mehrdad R. MAJLESSI, Ankur SHAH, Amber HILLIUS, Pamela DOUGLASS, Daniel KOLK
  • Publication number: 20230203581
    Abstract: Disclosed are formulations, including both liquid and lyophilized formulations, comprising a far-red dye probe and a non-linear surfactant or foamban. Also disclosed are related methods for preparing a lyophilized far-red dye probe formulation as well as related kits and diagnostic products.
    Type: Application
    Filed: October 13, 2022
    Publication date: June 29, 2023
    Applicant: Gen-Probe Incorporated
    Inventors: Sheila Aubin-Walker, Mehrdad R. Majlessi, Jimmykim Pham, Joshua Bousquet
  • Publication number: 20230087588
    Abstract: The disclosed disclosure is related to methods, compositions, and kits for targeting Adenovirus, Metapneumovirus, and/or Rhinovirus nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers. Kits and methods comprise at least one of these oligomers. Methods include uniplex and multiplex amplification and detection reactions.
    Type: Application
    Filed: August 17, 2022
    Publication date: March 23, 2023
    Inventors: Mehrdad R. MAJLESSI, Ankur Shah, Amber Hillius, Pamela Douglass, Daniel Kolk
  • Publication number: 20220372563
    Abstract: The disclosed disclosure is related to methods, compositions, and kits for targeting Adenovirus, Metapneumovirus, and/or Rhinovinis nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers. Kits and methods comprise at least one of these oligomers. Methods include uniplex and multiplex amplification and detection reactions.
    Type: Application
    Filed: June 7, 2022
    Publication date: November 24, 2022
    Inventors: Mehrdad R. MAJLESSI, Ankur SHAH, Amber HILLIUS, Pamela DOUGLASS, Daniel KOLK
  • Patent number: 11499193
    Abstract: Disclosed are formulations, including both liquid and lyophilized formulations, comprising a far-red dye probe and a non-linear surfactant or foamban. Also disclosed are related methods for preparing a lyophilized far-red dye probe formulation as well as related kits and diagnostic products.
    Type: Grant
    Filed: February 6, 2019
    Date of Patent: November 15, 2022
    Assignee: Gen-Probe Incorporated
    Inventors: Sheila Aubin-Walker, Mehrdad R. Majlessi, Jimmykim Pham, Joshua Bousquet
  • Publication number: 20220333162
    Abstract: Hybridization probe reagents that specifically detect nucleic acids of C. trachomatis, including wildtype and/or variant sequences identified as FI-nvCT C1515T (SEQ ID NO: 17), JP-nvCT C1522T (SEQ ID NO: 12), US-nvCT G1526A (SEQ ID NO:22), and NO-nvCT G1523A (SEQ ID NO:27). Certain probes include nucleotide analogs to enhance desirable binding properties.
    Type: Application
    Filed: September 3, 2020
    Publication date: October 20, 2022
    Inventors: Craig B. Clark, Damon K. Getman, Mehrdad R. Majlessi, Marion Walcher
  • Patent number: 11384387
    Abstract: The disclosed disclosure is related to methods, compositions, and kits for targeting Adenovirus, nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers. Kits and methods comprise at least one of these oligomers. Methods include uniplex and multiplex amplification and detection reactions.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: July 12, 2022
    Assignee: GEN-PROBE INCORPORATED
    Inventors: Mehrdad R. Majlessi, Ankur Shah, Amber Hillius, Pamela Douglass, Daniel Kolk
  • Publication number: 20210102201
    Abstract: Methods for capturing a target nucleic acid from a sample by using a capture probe that binds nonspecifically to the target nucleic acid and binds specifically to an immobilized probe via a specific binding pair that has one member on the capture probe and one member on the immobilized probe are disclosed. Compositions that include a capture probe that binds nonspecifically to a target nucleic acid and specifically to an immobilized probe via binding of members of a specific binding pair in a solution phase of a reaction mixture are disclosed.
    Type: Application
    Filed: December 18, 2020
    Publication date: April 8, 2021
    Inventors: Michael M. Becker, Mehrdad R. Majlessi
  • Patent number: 10900033
    Abstract: Methods for capturing a target nucleic acid from a sample by using a capture probe that binds nonspecifically to the target nucleic acid and binds specifically to an immobilized probe via a specific binding pair that has one member on the capture probe and one member on the immobilized probe are disclosed. Compositions that include a capture probe that binds nonspecifically to a target nucleic acid and specifically to an immobilized probe via binding of members of a specific binding pair in a solution phase of a reaction mixture are disclosed.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: January 26, 2021
    Assignee: Gen-Probe Incorporated
    Inventors: Michael M. Becker, Mehrdad R. Majlessi
  • Publication number: 20200263242
    Abstract: The disclosed disclosure is related to methods, compositions, and kits for targeting Adenovirus, Metapneumovirus, and/or Rhinovirus nucleic acid. Compositions include amplification oligomers and/or detection probe oligomers. Kits and methods comprise at least one of these oligomers. Methods include uniplex and multiplex amplification and detection reactions.
    Type: Application
    Filed: March 23, 2018
    Publication date: August 20, 2020
    Applicant: GEN-PROBE INCORPORATED
    Inventors: Mehrdad R. MAJLESSI, Ankur SHAH, Amber HILLIUS, Pamela DOUGLASS, Daniel KOLK
  • Publication number: 20200048721
    Abstract: This disclosure concerns amplification primers, hybridization assay probes, compositions containing such primers and probes, and associated reagents, kits, and methods, that can be used to analyze samples for the presence of Influenza A virus, Influenza B virus, Respiratory Syncytial Virus A, and/or Respiratory Syncytial Virus B target nucleic acids.
    Type: Application
    Filed: March 23, 2018
    Publication date: February 13, 2020
    Applicant: GEN-PROBE INCORPORATED
    Inventors: Matthias JOST, Pamela DOUGLASS, Daniel P. KOLK, Mehrdad R. MAJLESSI
  • Publication number: 20190241956
    Abstract: Disclosed are formulations, including both liquid and lyophilized formulations, comprising a far-red dye probe and a non-linear surfactant or foamban. Also disclosed are related methods for preparing a lyophilized far-red dye probe formulation as well as related kits and diagnostic products.
    Type: Application
    Filed: February 6, 2019
    Publication date: August 8, 2019
    Inventors: Sheila AUBIN-WALKER, Mehrdad R. MAJLESSI, Jimmykim PHAM, Joshua BOUSQUET
  • Publication number: 20160122746
    Abstract: Methods for capturing a target nucleic acid from a sample by using a capture probe that binds nonspecifically to the target nucleic acid and binds specifically to an immobilized probe via a specific binding pair that has one member on the capture probe and one member on the immobilized probe are disclosed. Compositions that include a capture probe that binds nonspecifically to a target nucleic acid and specifically to an immobilized probe via binding of members of a specific binding pair in a solution phase of a reaction mixture are disclosed.
    Type: Application
    Filed: January 7, 2016
    Publication date: May 5, 2016
    Inventors: Michael M. BECKER, Mehrdad R. MAJLESSI
  • Patent number: 9051601
    Abstract: Methods for capturing a target nucleic acid from a sample by using a capture probe that binds nonspecifically to the target nucleic acid and binds specifically to an immobilized probe via a specific binding pair that has one member on the capture probe and one member on the immobilized probe are disclosed. Compositions that include a capture probe that binds nonspecifically to a target nucleic acid and specifically to an immobilized probe via binding of members of a specific binding pair in a solution phase of a reaction mixture are disclosed.
    Type: Grant
    Filed: August 1, 2007
    Date of Patent: June 9, 2015
    Assignee: Gen-Probe Incorporated
    Inventors: Michael M. Becker, Mehrdad R. Majlessi
  • Patent number: 8551766
    Abstract: Kits, reaction mixtures and methods for separating a target nucleic acid from a sample by using at least one hairpin capture probe oligonucleotide that has the structure 5?-X.sub.n a? b? c? Y.sub.n-3?, wherein X and Y each comprise nucleic acid sequences that can form a double stranded stem portion, one of X or Y is a capture sequence that is a first member of a specific binding pair and the other of X or Y is a terminal sequence of the hairpin capture probe, and a? b? c? comprises a target-complementary sequence flanked by X and Y to thereby form a loop portion of the hairpin, thus forming a capture hybrid that is separated from other sample components before the target nucleic acid is released from the capture support and hybridized to a detection probe that hybridizes specifically to the same sequence that is at least partially hybridized by the a? b? c? portion of the capture probe, thus forming a detectable detection hybrid to indicate the presence of the target nucleic acid in the sample.
    Type: Grant
    Filed: July 28, 2010
    Date of Patent: October 8, 2013
    Assignee: Gen-Probe Incorporated
    Inventors: Michael M. Becker, Mehrdad R. Majlessi
  • Publication number: 20130209992
    Abstract: Methods for capturing a target nucleic acid from a sample by using a capture probe that binds nonspecifically to the target nucleic acid and binds specifically to an immobilized probe via a specific binding pair that has one member on the capture probe and one member on the immobilized probe are disclosed. Compositions that include a capture probe that binds nonspecifically to a target nucleic acid and specifically to an immobilized probe via binding of members of a specific binding pair in a solution phase of a reaction mixture are disclosed.
    Type: Application
    Filed: February 15, 2013
    Publication date: August 15, 2013
    Applicant: Gen-Probe Incorporated
    Inventors: Michael M. BECKER, Mehrdad R. MAJLESSI
  • Patent number: 8460869
    Abstract: Methods of the invention separate a target nucleic acid from a sample by using at least one capture probe oligonucleotide that contains a target-complementary region and a member of a specific binding pair that attaches the target nucleic acid to an immobilized probe on a capture support, thus forming a capture hybrid that is separated from other sample components before the target nucleic acid is released from the capture support and hybridized to a detection probe to form a detection hybrid that produces a detectable signal that indicates the presence of the target nucleic acid in the sample. Compositions for practicing the methods of the invention include a capture probe oligonucleotide made up a target-complementary region sequence and a covalently linked capture region sequence that includes a member of a specific binding pair.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: June 11, 2013
    Assignee: Gen-Probe Incorporated
    Inventors: Michael M. Becker, Mehrdad R. Majlessi
  • Publication number: 20120231551
    Abstract: Kits, reaction mixtures and methods for separating a target nucleic acid from a sample by using at least one hairpin capture probe oligonucleotide that has the structure 5?-X.sub.n a? b? c? Y.sub.n-3?, wherein X and Y each comprise nucleic acid sequences that can form a double stranded stem portion, one of X or Y is a capture sequence that is a first member of a specific binding pair and the other of X or Y is a terminal sequence of the hairpin capture probe, and a? b? c? comprises a target-complementary sequence flanked by X and Y to thereby form a loop portion of the hairpin, thus forming a capture hybrid that is separated from other sample components before the target nucleic acid is released from the capture support and hybridized to a detection probe that hybridizes specifically to the same sequence that is at least partially hybridized by the a? b? c? portion of the capture probe, thus forming a detectable detection hybrid to indicate the presence of the target nucleic acid in the sample.
    Type: Application
    Filed: July 28, 2010
    Publication date: September 13, 2012
    Applicant: GEN-PROBE INCORPORATED
    Inventors: Michael M. BECKER, Mehrdad R. MAJLESSI