Abstract: Fluid connector assemblies that seal off fluid paths in the respective connectors are disclosed. When connectors of a fluid connector assembly are connected to each other, respective compressible members in the connectors are displaced, allowing downstream fluid passage through the fluid connector assembly. The connectors maintain a connection by a snap mechanism that provides a threshold retention force. When an external force greater than the threshold force is applied to the fluid connector assembly, the snap mechanism may no longer maintain the connectors together, causing the connectors to decouple from each other. However, each of the compressible members can return to their respective original positions and shapes to seal off respective fluid paths in the connectors, thus preventing further downstream and upstream flow through the fluid connector assembly and limiting or preventing fluid loss.

Abstract: A flow restriction device includes a proximal housing configured to couple to a fluid collection device, a distal housing configured to couple to a catheter assembly, an intermediate housing interposed between the proximal housing and the distal housing and an internal fluid channel extending transversely therethrough. The flow restriction device also includes a fluid shield assembly having an enclosure coupled to an end of the distal housing and a split septum coupled to an end of the enclosure, the split septum comprising a flexible material with a centrally disposed slit. The fluid shield assembly provides for connection of a female connector to a male connector of the distal housing through the slit of the split septum, and to contain fluid within the enclosure and split septum upon disconnection and withdrawal of the female connector from the male connector. Blood collection systems and fluid shield assemblies are also provided.

Abstract: A fluid connector device for a blood collection system is disclosed. In order to be safely used with different gauges, the fluid connector device can regulate blood flow therethrough based upon the catheter gauge. For example, when 18-to-22-gauge catheters are used, the fluid connector device regulates the blood flow by positioning a slider assembly (within the fluid connector device) to a setting that allows a single channel to transmit blood through the fluid connector device into a fluid inlet and out of a fluid outlet of the fluid connector device. Alternatively, in another example, when 24-gauge (or greater) catheters are used, the slider assembly can be actuated to a new position, which allows multiple channels to transmit blood into the fluid inlet and out of the fluid outlet. By regulating blood flow, the fluid connector device can limit or prevent hemolysis, while being universally used with different catheters.

Abstract: Pump assemblies for use with an IV set are described herein. A pump assembly includes a rotatable crank, a piston rod, and a diaphragm assembly. The crank includes a crank profile defining a plurality of lobes. The piston rod includes a first follower and a second follower spaced apart from the first follower. The rotation of the crank relative to the piston rod causes the piston rod to reciprocate relative to the crank. The diaphragm assembly includes a housing and a diaphragm member. The diaphragm member is coupled to the housing and cooperatively defines a volume in fluid communication with the IV set. The diaphragm member is movable between an extended position configured to draw in fluid from the IV set and a contracted position configured to expel fluid into the IV set. The diaphragm member is coupled to the piston rod to reciprocate the diaphragm member.

Abstract: A flow restriction device may include a male luer connector portion, a female luer connector portion, and a flexible tube. The male luer connector portion defies a first lumen. The female luer connector portion defines a second lumen. The flexible tube defines a third lumen. The third lumen is in fluid communication with the first lumen and the second lumen. The third lumen has a diameter of about 0.02 inches.

Abstract: A pressure detection system includes a body having an internal chamber with input and output ports and a flexible membrane fluidically sealed to an exposed opening of the chamber to prevent a fluid passing through the chamber from passing through the exposed opening. The membrane is configured to change shape responsive to an increase in pressure caused by the fluid within the chamber satisfying a predetermined threshold. In some implementations, the membrane includes or is part of an identification mechanism which moves outwards, away from the chamber, as the pressure increases to indicate the pressure increase. In some implementations, the identification mechanism includes markings on the surface of the membrane, and an image sensing device reads the markings, and provides an indication of a current pressure associated with the fluid in the chamber based on a variation in the markings from a default state.

Abstract: A flow restriction device including a housing forming a fluid flow path with a resilient valve positioned between first and second segments of the fluid path, where a segment of the fluid path includes a spiral or involute shape, and where the resilient valve is responsive to a change in pressure along the fluid path such that the resilient valve can move or bias toward the fluid path to restrict a fluid flow through the fluid path, thereby reducing a flow rate and pressure of the fluid, and where the fluid is blood, reducing the hemolysis index of the blood, and in some instances the resilient valve stopping the fluid flow through the fluid flow path responsive to exceeding a pressure along the fluid path to reduce the hemolysis index of the blood.

Abstract: Fluid connector systems that can include first and second valve assemblies that are couplable together to form a fluid pathway through the fluid connector system when the first and second valve assemblies are coupled together, and can resist fluid flow through each of the first and second valve assemblies when the first and second valve assemblies are separated from each other, where the first and second valve assemblies can include a compressible element or post positioned within a channel and configured resist fluid flow through the respective first or second valve assembly in a first position and to reduce the resistance to fluid flow through the first or second valve assembly in a second position, and the first and second valve assemblies including a sleeve and one or more arm configured to engage each other to form a snap fitting feature that can resist separation therebetween.

Abstract: A flow restriction device may include a male luer connector portion, a female luer connector portion, a tube, and an overmolded body portion. The male luer connector portion defies a first lumen. The female luer connector portion defines a second lumen. The tube defines a third lumen. The third lumen is in fluid communication with the first lumen and the second lumen. The third lumen has a diameter less than 0.025 inches. The overmolded body portion is formed around the tube.

Abstract: Fluid clamps are described herein. A fluid clamp includes a clamp body and a rotating body. The clamp body includes a first and second valve element. Each valve element includes a valve extension portion and a valve end portion extending from the valve extension portion. The first and second valve elements are disposed opposite to each other to allow a tubing to pass between the first and second valve elements. The rotating body is rotatably coupled to the clamp body. The rotation of the rotating body moves the valve end portion of at least one of the first and second valve elements to adjust a flow rate through the tubing.

Abstract: A flow restriction device may include a male luer connector portion and a female luer connector portion. The male luer connector portion can define a cavity and a first lumen in fluid-flow continuity with the cavity. The female luer connector portion defines a second lumen and an extension in fluid-flow continuity with the second lumen. The extension includes a first end, a second end, an outer surface, and a channel. The channel is defined on the outer surface. The channel is helically disposed around the outer surface of the extension and extends between the first and second ends. The extension is configured to be at least partially disposed within the cavity. The channel and the inner surface of the cavity define a fluid passage in fluid-flow continuity with the first lumen and the second lumen.

Abstract: A flow restriction device may include a housing and an insert body. The housing defines a first lumen, a second lumen, and a cavity disposed between the first lumen and the second lumen. The insert body can be disposed within the cavity. The insert body includes a first end, a second end, a longitudinal axis extending through the first and second ends, an outer surface, and a channel. The channel is defined on the outer surface. The channel extends between the first and second ends. The channel includes a first portion that extends in a first direction away from the longitudinal axis and a second portion that extends in a second direction toward the longitudinal axis. The channel and an inner surface of the cavity define a fluid passage in fluid communication with the first lumen and the second lumen.

Abstract: Methods for selecting a filter for a filtration process are described. Input data is received, and based on the input data, one or more filter characteristics for each of a plurality of filter candidates for a filtration process are identified. Process parameters of the filtration process are identified. A computer-implemented simulation process of the filtration process for each of the plurality of filter candidates is performed, based on the identified process parameters and identified filter characteristics. One or more output characteristics of the filtration process are determined based on the simulation. A filter candidate of the plurality of filter candidates is selected based on the one or more output characteristics.

Abstract: A flow restriction device may include a housing with first and second end portions forming respective first and second openings, and a cavity configured to receive an insert body defining a fluid passage that extends from a first opening of the housing at the first end portion to a second opening of the housing at the second end portion, where the fluid passage extends in more than one direction along a path between the first and second end portions of the housing to induce a resistance to a fluid flow moving through the device, thereby reducing a flow rate and pressure of the fluid, and where the fluid is blood, reduce the hemolysis index of the blood.

Abstract: A mini peristaltic pump is provided that includes a base plate, first and second gears disposed on a first side of the base plate, first and second roller wheels disposed on a second side of the base plate and coupled to the first and second gears, respectively, and one or more rollers coupled to each of the first and second roller wheels. A motor is coupled to the first gear, the motor configured to rotate the first gear and the first roller wheel to move the one or more rollers coupled to the first roller wheel in a first orbital path to peristaltically engage and compress a hand pump disposed between the first and second roller wheels. A profile feature on the base may be provided instead of the second gear and roller wheel. Systems and methods are also provided.

Abstract: Methods for selecting a filter for a filtration process are described. Input data is received, and based on the input data, one or more filter characteristics for each of a plurality of filter candidates for a filtration process are identified. Process parameters of the filtration process are identified. A computer-implemented simulation process of the filtration process for each of the plurality of filter candidates is performed, based on the identified process parameters and identified filter characteristics. One or more output characteristics of the filtration process are determined based on the simulation. A filter candidate of the plurality of filter candidates is selected based on the one or more output characteristics.

Abstract: A system for simultaneously transporting internet protocol voice traffic and power to an internet protocol telephony transport using the existing twisted pair infrastructure of a traditional phone system. The system includes a twisted pair broadband switch. The twisted pair broadband switch connects on one end to an internet protocol telephone voice switch using Ethernet wiring and connects on another end to a media converter using a twisted pair wiring on the existing twisted pair infrastructure. The media converter condition the voice traffic between a twisted pair interface and an Ethernet interface to allow connection to an internet protocol telephone. Power is simultaneously transported with the voice traffic over the same twisted pair wiring of the existing twisted pair infrastructure.