Patents by Inventor Mei Cong

Mei Cong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for monitoring transmembrane trafficking
    Patent number: 9738921
    Abstract: Provided herein are compositions and methods for monitoring the movement of analytes and/or cellular components across biological membranes (e.g., cell surface internalization). In particular, reporter constructs are provided, the transmembrane movement of which (e.g., by endocytosis) is monitored by methods described herein.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: August 22, 2017
    Assignee: Promega Corporation
    Inventors: Brock F. Binkowski, Mei Cong, Matthew B. Robers
  • pH sensors
    Patent number: 9702824
    Abstract: Provided herein are fluorescent sensor agents, and methods of use and manufacture thereof. In particular, sensor agents are provided that exhibit a detectable change in fluorescence (e.g., fluorescence intensity) upon alteration of the pH of the surrounding environment (e.g., upon moving from one pH environment to another).
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: July 11, 2017
    Assignee: PROMEGA CORPORATION
    Inventors: Mei Cong, Cesear Corona, Mark G. McDougall, Chad Zimprich
  • SYSTEMS AND METHODS FOR ASSESSING MODULATORS OF IMMUNE CHECKPOINTS
    Publication number: 20160169869
    Abstract: Provided herein are compositions, systems, and methods for assessing modulators of immune checkpoints. In particular, artificial antigen presenting cells (aAPCs) and immune effector cells are provided to assess the potency of test agents to inhibit immune checkpoints.
    Type: Application
    Filed: November 20, 2015
    Publication date: June 16, 2016
    Inventors: Mei Cong, Zhijie Jey Cheng, Natasha Karassina, Jamison Grailer, Frank Fan
  • COMPOSITIONS AND METHODS FOR MONITORING TRANSMEMBRANE TRAFFICKING
    Publication number: 20150322482
    Abstract: Provided herein are compositions and methods for monitoring the movement of analytes and/or cellular components across biological membranes (e.g., cell surface internalization). In particular, reporter constructs are provided, the transmembrane movement of which (e.g., by endocytosis) is monitored by methods described herein.
    Type: Application
    Filed: July 15, 2015
    Publication date: November 12, 2015
    Inventors: Brock F. Binkowski, Mei Cong, Matthew B. Robers
  • Compositions and methods for monitoring transmembrane trafficking
    Patent number: 9096889
    Abstract: Provided herein are compositions and methods for monitoring the movement of analytes and/or cellular components across biological membranes (e.g., cell surface internalization). In particular, reporter constructs are provided, the transmembrane movement of which (e.g., by endocytosis) is monitored by methods described herein.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: August 4, 2015
    Assignee: PROMEGA CORPORATION
    Inventors: Brock F. Binkowski, Mei Cong, Matthew B. Robers
  • pH SENSORS
    Publication number: 20150044776
    Abstract: Provided herein are fluorescent sensor agents, and methods of use and manufacture thereof. In particular, sensor agents are provided that exhibit a detectable change in fluorescence (e.g., fluorescence intensity) upon alteration of the pH of the surrounding environment (e.g., upon moving from one pH environment to another).
    Type: Application
    Filed: March 8, 2013
    Publication date: February 12, 2015
    Applicant: PROMEGA CORPORATION
    Inventors: Mei Cong, Cesear Corona, Mark G. McDougall, Chad Zimprich
  • COMPOSITIONS AND METHODS FOR MONITORING TRANSMEMBRANE TRAFFICKING
    Publication number: 20130196357
    Abstract: Provided herein are compositions and methods for monitoring the movement of analytes and/or cellular components across biological membranes (e.g., cell surface internalization). In particular, reporter constructs are provided, the transmembrane movement of which (e.g., by endocytosis) is monitored by methods described herein.
    Type: Application
    Filed: November 21, 2012
    Publication date: August 1, 2013
    Inventors: Brock F. Binkowski, Mei Cong, Matthew B. Robers
  • METHOD FOR USING DIVISION ARRESTED CELLS IN SCREENING ASSAYS
    Publication number: 20120276545
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: May 1, 2012
    Publication date: November 1, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Thomas LIVELLI, Zhong Zhong, Mark Federici, Mei Cong
  • METHOD FOR USING DIVISION ARRESTED CELLS IN SCREENING ASSAYS
    Publication number: 20110275101
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: May 6, 2011
    Publication date: November 10, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Thomas LIVELLI, Zhong Zhong, Mark Federici, Mei Cong
  • Method for using division arrested cells in screening assays
    Patent number: 7960101
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Grant
    Filed: January 11, 2010
    Date of Patent: June 14, 2011
    Assignee: Life Technologies Corporation
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong
  • METHOD FOR USING DIVISION ARRESTED CELLS IN SCREENING ASSAYS
    Publication number: 20100203561
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: January 11, 2010
    Publication date: August 12, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Thomas LIVELLI, Zhong Zhong, Mark Federici, Mei Cong
  • Method for Using Division Arrested Cells in Screening Assays
    Publication number: 20080248516
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: June 12, 2008
    Publication date: October 9, 2008
    Applicant: INVITROGEN CORPORATION
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong
  • METHOD FOR USING DIVISION ARRESTED CELLS IN SCREENING ASSAYS
    Publication number: 20080081327
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: July 10, 2007
    Publication date: April 3, 2008
    Applicant: INVITROGEN CORPORATION
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong
  • Method for using division arrested cells in screening assays
    Publication number: 20060148007
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: February 27, 2006
    Publication date: July 6, 2006
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong
  • Method for using division arrested cells in screening assays
    Patent number: 7045281
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Grant
    Filed: September 20, 2002
    Date of Patent: May 16, 2006
    Assignee: Cell & Molecular Technologies, Inc.
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong
  • Method for using division arrested cells in screening assays
    Publication number: 20040058329
    Abstract: Division arrested cells are used in screening assays to determine the effect of a substance of interest on the cells. The division arrested cells can be used in drug screening assays, signal transduction assays, and are especially useful in large scale, high throughput assays.
    Type: Application
    Filed: September 20, 2002
    Publication date: March 25, 2004
    Inventors: Thomas Livelli, Zhong Zhong, Mark Federici, Mei Cong