Patents by Inventor Mei Hua Jiang

Mei Hua Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11052120
    Abstract: The present application provides an in-vitro committed differentiation method for inducing human induced pluripotent stem cells (hiPSCs) into Leydig cells (LCs) by neural crest stem cells (NCSCs). The hiPS-derived LCs is verified by an animal model to have the capacity of regenerating senile or injured LCs, so that a new treatment for supplementing testosterone is provided for patients suffering from hypogonadism, particularly for patients suffering from late-onset hypogonadism (LOH).
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: July 6, 2021
    Assignee: SUN YAT-SEN UNIVERSITY
    Inventors: Peng Xiang, Mei Hua Jiang, Weiqiang Li
  • Publication number: 20180311286
    Abstract: The present application provides an in-vitro committed differentiation method for inducing human induced pluripotent stem cells (hiPSCs) into Leydig cells (LCs) by neural crest stem cells (NCSCs). The hiPS-derived LCs is verified by an animal model to have the capacity of regenerating senile or injured LCs, so that a new treatment for supplementing testosterone is provided for patients suffering from hypogonadism, particularly for patients suffering from late-onset hypogonadism (LOH).
    Type: Application
    Filed: May 24, 2018
    Publication date: November 1, 2018
    Inventors: Peng Xiang, Mei Hua Jiang, Weiqiang Li
  • Patent number: 9078851
    Abstract: The present invention relates to a novel use of substance P. The substance P of the present invention exhibits effects of decreasing microglia activity, decreasing proinflammatory cytokines, inhibiting apoptosis, etc. The substance P of the present invention effectively treats degenerative central nervous system diseases or disorders such as a spinal cord injury caused by a traumatic injury (flexion injury, vertical compression injury, hyperextension injury, flexion-rotation injury) and by a non-traumatic injury (vascular dysfunction, arthritis, or degenerative arthritis), Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, depressive disorder, epilepsy, etc.
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: July 14, 2015
    Assignee: UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE
    Inventors: Young Sook Son, Mei Hua Jiang
  • Publication number: 20120225821
    Abstract: The present invention relates to a novel use of substance P. The substance P of the present invention exhibits effects of decreasing microglia activity, decreasing proinflammatory cytokines, inhibiting apoptosis, etc. The substance P of the present invention effectively treats degenerative central nervous system diseases or disorders such as a spinal cord injury caused by a traumatic injury (flexion injury, vertical compression injury, hyperextension injury, flexion-rotation injury) and by a non-traumatic injury (vascular dysfunction, arthritis, or degenerative arthritis), Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, depressive disorder, epilepsy, etc.
    Type: Application
    Filed: August 17, 2010
    Publication date: September 6, 2012
    Applicant: University-Industry Cooperation Group of Kyung Hee
    Inventors: Young Sook Son, Mei Hua Jiang