Patents by Inventor Mei Huei Jang

Mei Huei Jang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for purification of arylsulfatase A
    Patent number: 11884945
    Abstract: The present invention provides, among other things, improved methods for purifying arylsulfatase A (ASA) protein produced recombinantly for enzyme replacement therapy. The present invention is, in part, based on the surprising discovery that recombinant ASA protein can be purified from unprocessed biological materials, such as, ASA-containing cell culture medium, using a process involving as few as four chromatography columns and only one step of post-chromatographic ultrafiltration/diafiltration.
    Type: Grant
    Filed: July 1, 2022
    Date of Patent: January 30, 2024
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Dave Nichols, Igor Quinones-Garcia, Bee Lin Cheang, Mei Huei Jang
  • METHODS FOR PURIFICATION OF ARYLSULFATASE A
    Publication number: 20230235303
    Abstract: The present invention provides, among other things, improved methods for purifying arylsulfatase A (ASA) protein produced recombinantly for enzyme replacement therapy. The present invention is, in part, based on the surprising discovery that recombinant ASA protein can be purified from unprocessed biological materials, such as, ASA-containing cell culture medium, using a process involving as few as four chromatography columns and only one step of post-chromatographic ultrafiltration/diafiltration.
    Type: Application
    Filed: July 1, 2022
    Publication date: July 27, 2023
    Inventors: Dave Nichols, Igor Quinones-Garcia, Bee Lin Cheang, Mei Huei Jang
  • Methods for purification of arysulfatase A
    Patent number: 11407984
    Abstract: The present invention provides, among other things, improved methods for purifying arylsulfatase A (ASA) protein produced recombinantly for enzyme replacement therapy. The present invention is, in part, based on the surprising discovery that recombinant ASA protein can be purified from unprocessed biological materials, such as, ASA-containing cell culture medium, using a process involving as few as four chromatography columns and only one step of post-chromatographic ultrafiltration/diafiltration.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: August 9, 2022
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Dave Nichols, Igor Quinones-Garcia, Mei Huei Jang, Bee Lin Cheang
  • METHODS FOR PURIFICATION OF ARYSULFATASE A
    Publication number: 20150353904
    Abstract: The present invention provides, among other things, improved methods for purifying arylsulfatase A (ASA) protein produced recombinantly for enzyme replacement therapy. The present invention is, in part, based on the surprising discovery that recombinant ASA protein can be purified from unprocessed biological materials, such as, ASA-containing cell culture medium, using a process involving as few as four chromatography columns and only one step of post-chromatographic ultrafiltration/diafiltration.
    Type: Application
    Filed: January 9, 2014
    Publication date: December 10, 2015
    Inventors: Dave Nichols, Igor Quinones-Garcia, Bee Lin Cheang, Mei Huei Jang