Abstract: This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help restore heart function. According to certain embodiments, a fluid-induced shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for the regenerative repair of diseases, such as diseased heart tissues. Therefore, compositions comprising the exosomes derived from stem cells and methods of treating a degenerative disease by administering the exosomes isolated from stem cells are also provided.

Abstract: A human-eye state detection device is provided, which includes an image capturing device and a processor. The image capturing device is configured to continuously capture a plurality of frames of facial images of a user. The processor determines an eye area from the frames of facial images, and calculates an eye-opening average based on the eye area. The processor repeatedly updates the eye-opening threshold based on the average eye-opening value. In response to the average eye-opening value being less than the eye-opening threshold, the processor determines that the user is in an eye-closing state.

Abstract: A power semiconductor device includes: a die carrier; a power semiconductor die arranged on the die carrier and having a first side and an opposite second side, the first side facing away from the die carrier and including a first power terminal having a Cu layer and the second side including a second power terminal electrically coupled to the die carrier; a contact clip electrically coupled to the Cu layer of the first power terminal by a solder joint; and a patterned cover layer deposited on the first side of the power semiconductor die. The cover layer surrounds the first power terminal on at least one lateral side. The cover layer is arranged over the Cu layer. The cover layer consists of Al2O3 or SiO2.

Abstract: A method for adapting a shared organization device for different users of a plurality of users includes: identifying a first user of the plurality of users associated with the shared organization device that is interacting with the shared organization device based on a first user input; determining one or more user-associated display settings for the first user based on a physical ability and a cognitive ability of the first user; displaying an interactive user interface of the shared organization device based on the one or more user-associated display settings for the first user, comprising: displaying one or more interactive affordances at a first location of the touch screen display based on the physical ability of the first user, and displaying one or more symbolic representations of one or more tasks assigned to the first user based on the cognitive ability of the first user.

Abstract: The present invention discloses an electrodeposited copper foil with a uniform matte surface. The electrodeposited copper foil of the present invention has an average thickness (TAve) of about 30 ?m to about 400 ?m; and the matte surface of the present electrodeposited copper foil has a uniformity factor (UF) of 5.5 ?m or less. Also disclosed are methods for manufacturing the present electrodeposited copper foils and articles made therefrom.

Abstract: This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help prevent or reduce scar tissue growth in cardiovascular system and restore heart function. According to certain embodiments, a fluid-induced, pathological shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for preventing or reducing scar tissue growth in cardiovascular system. Therefore, compositions comprising the exosomes derived from stem cells and methods of preventing and/or treating scar tissue growth in cardiovascular system by administering the exosomes isolated from stem cells are also provided.

Abstract: The invention relates to a process for the preparation of a catalyst ink formulation, said process comprising the steps of: (i) providing a mixture comprising a catalyst, an ionomer and water that has been subjected to ball milling; and (ii) subjecting the mixture to an ultrasonication step for a time period of from about 1 minute to about 1 hour.

Abstract: Apparatus and methods for utilizing non-fungible tokens (“NFTs”) for payment redemption and remittances are provided. A payor may use a computer program product to create an NFT. The NFT may include a digital envelope and metadata. The digital envelope may include one or more payment terms as a payment statement and the payment funds. The NFT may be transferred to a digital wallet belonging to a payee. The payee may select an option to redeem the payment funds. The payment funds may be transferred to the payee per the selection.

Abstract: The present disclosure provides electroporation cartridges for single use electroporation as well as electroporation cartridges for automated batch processing, electroporation instruments and systems and methods of electroporation using these devices and systems. In some embodiments, electroporation cartridges comprise an electroporation chamber defined by an elongate body, a first electrode at a proximal end and a second electrode at a distal end of a chamber. Electroporation systems of the disclosure include one or more components including a pulse generator, compartments for placing either flow-through or single use electroporation cartridges, components for storage of cells, cooling and pre-cooling mechanisms, removably insertable modular casings having compartments for holding and arranging electroporation system and reagent components, one or more pumps for moving sample through the system, and processors and controllers.

Abstract: A method includes: forming a barrier layer in a substrate; depositing a first dielectric layer over the substrate; forming a patterned mask layer over the first dielectric layer; patterning the first dielectric layer into a first sublayer of a gate dielectric layer; converting at least part of the patterned mask layer into a second sublayer of the gate dielectric layer; depositing a second dielectric layer adjacent to the first and second sublayers to serve as a third sublayer of the gate dielectric layer; and depositing a gate electrode over the gate dielectric layer.

Abstract: Apparatus and methods for utilizing non-fungible tokens (“NFTs”) for payment redemption and remittances are provided. A payor may use a computer program product to create an NFT. The NFT may include a digital envelope and metadata. The digital envelope may include one or more payment terms as a payment statement and the payment funds. The NFT may be transferred to a digital wallet belonging to a payee. The payee may select an option to redeem the payment funds. The payment funds may be transferred to the payee per the selection.

Abstract: In a method for multipath reflection correction of acoustic signals received at an ultrasonic sensor, characteristics of multipath reflection signals of the ultrasonic sensor are accessed, wherein the characteristics of the multipath reflection signals include a relationship of primary signal contributions to multipath reflection signal contributions for acoustic signals received at the ultrasonic sensor at a plurality of times of flight for a plurality of locations of the ultrasonic sensor. Acoustic signals are received at the ultrasonic sensor over a time of flight range while a target is interacting with the ultrasonic sensor, wherein the acoustic signals include a primary signal contribution and a multipath reflection signal contribution. The characteristics of the multipath reflection signals are compared to received acoustic signals.

Abstract: Apparatus and methods for utilizing non-fungible tokens (“NFTs”) for payment redemption and remittances are provided. A payor may use a computer program product to create an NFT. The NFT may include a digital envelope and metadata. The digital envelope may include one or more payment terms as a payment statement and the payment funds. The NFT may be transferred to a digital wallet belonging to a payee. The payee may select an option to redeem the payment funds. The payment funds may be transferred to the payee per the selection.

Abstract: This application describes an autonomous system for utilizing a non-fungible token (“NFT”) to manage dynamic operational conditions applied to bank account. The autonomous system may include a dynamic NFT stored on a distributed ledger. The dynamic NFT may include non-editable fields and editable fields. The autonomous system may include a static NFT stored on the distributed ledger. The dynamic and static NFTs may be linked to an account. The static NFT may define operating conditions for the non-editable account number. The autonomous system may include a smart contract that executes on the distributed ledger. The smart contract may detect a change in a value stored in the editable field of the dynamic NFT. The smart contract may locate operating conditions stored in the static NFT. Based on the operating conditions and the value, the smart contract may take action to manage the corresponding account.

Abstract: This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help restore heart function. According to certain embodiments, a fluid-induced shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for the regenerative repair of diseases, such as diseased heart tissues. Therefore, compositions comprising the exosomes derived from stem cells and methods of treating a degenerative disease by administering the exosomes isolated from stem cells are also provided.

Abstract: This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help restore heart function. According to certain embodiments, a fluid-induced shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for the regenerative repair of diseases, such as diseased heart tissues. Therefore, compositions comprising the exosomes derived from stem cells and methods of treating a degenerative disease by administering the exosomes isolated from stem cells are also provided.

Abstract: The present disclosure is directed to devices, systems and methods that include a stage and an actuator configured to transmit a orthogonal force to the stage, wherein the actuator is configured to receive a plurality of orthogonal acceleration signals, wherein the orthogonal acceleration signals comprise an actuator frequency signal and an actuator magnitude signal.