Patents by Inventor Mei-Ling Liou

Mei-Ling Liou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR THE ACTIVATION OF GAMMA-DELTA T-CELLS
    Publication number: 20230340531
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Application
    Filed: November 1, 2022
    Publication date: October 26, 2023
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • METHODS AND COMPOSITIONS FOR THE ACTIVATION OF GAMMA-DELTA T-CELLS
    Publication number: 20230277579
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Application
    Filed: November 15, 2022
    Publication date: September 7, 2023
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • Methods and compositions for the activation of gamma-delta T-cells
    Patent number: 11534450
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: December 27, 2022
    Assignee: American Gene Technologies International Inc.
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • Methods and compositions for the activation of gamma-delta T-cells
    Patent number: 11519006
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: December 6, 2022
    Assignee: American Gene Technologies International Inc.
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • COMBINATION VECTORS AND METHODS FOR TREATING CANCER
    Publication number: 20220251563
    Abstract: A composition for treating cancer is disclosed. The composition includes a lentiviral particle and an aminobisphosphonate drug. The lentiviral particle is capable of infecting a target cell, such as a cancer cell, and includes an envelope protein optimized for targeting such target cell and a viral vector. The viral vector includes a small RNA optimized to target an FDPS mRNA sequence. The aminobisphosphonate drug includes zoledronic acid.
    Type: Application
    Filed: January 6, 2022
    Publication date: August 11, 2022
    Inventors: Tyler Lahusen, Mei-Ling Liou, Lingzhi Xiao, Haishan Li, Charles David Pauza
  • Combination vectors and methods for treating cancer
    Patent number: 11242527
    Abstract: A composition for treating cancer is disclosed. The composition includes a lentiviral particle and an aminobisphosphonate drug. The lentiviral particle is capable of infecting a target cell, such as a cancer cell, and includes an envelope protein optimized for targeting such target cell and a viral vector. The viral vector includes a small RNA optimized to target an FDPS mRNA sequence. The aminobisphosphonate drug includes zoledronic acid.
    Type: Grant
    Filed: March 10, 2021
    Date of Patent: February 8, 2022
    Assignee: American Gene Technologies International Inc.
    Inventors: Tyler Lahusen, Mei-Ling Liou, Lingzhi Xiao, Haishan Li, Charles David Pauza
  • Combination vectors and methods for treating cancer
    Patent number: 10975374
    Abstract: A composition for treating cancer is disclosed. The composition includes a lentiviral particle and an aminobisphosphonate drug. The lentiviral particle is capable of infecting a target cell, such as a cancer cell, and includes an envelope protein optimized for targeting such target cell and a viral vector. The viral vector includes a small RNA optimized to target an FDPS mRNA sequence. The aminobisphosphonate drug includes zoledronic acid.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: April 13, 2021
    Assignee: American Gene Technologies International Inc.
    Inventors: Tyler Lahusen, Mei-Ling Liou, Lingzhi Xiao, Haishan Li, Charles David Pauza
  • COMBINATION VECTORS AND METHODS FOR TREATING CANCER
    Publication number: 20210047644
    Abstract: A composition for treating cancer is disclosed. The composition includes a lentiviral particle and an aminobisphosphonate drug. The lentiviral particle is capable of infecting a target cell, such as a cancer cell, and includes an envelope protein optimized for targeting such target cell and a viral vector. The viral vector includes a small RNA optimized to target an FDPS mRNA sequence. The aminobisphosphonate drug includes zoledronic acid.
    Type: Application
    Filed: July 30, 2020
    Publication date: February 18, 2021
    Inventors: Tyler Lahusen, Mei-Ling Liou, Lingzhi Xiao, Haishan Li, Charles David Pauza
  • METHODS AND COMPOSITIONS FOR THE ACTIVATION OF GAMMA-DELTA T-CELLS
    Publication number: 20210008093
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Application
    Filed: August 7, 2020
    Publication date: January 14, 2021
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • Methods and compositions for the activation of gamma-delta T-cells
    Patent number: 10772905
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: September 15, 2020
    Assignee: American Gene Technologies International Inc.
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • Combination vectors and methods for treating cancer
    Patent number: 10767183
    Abstract: A composition for treating cancer is disclosed. The composition includes a lentiviral particle and an aminobisphosphonate drug. The lentiviral particle is capable of infecting a target cell, such as a cancer cell, and includes an envelope protein optimized for targeting such target cell and a viral vector. The viral vector includes a small RNA optimized to target an FDPS mRNA sequence. The aminobisphosphonate drug includes zoledronic acid.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: September 8, 2020
    Assignee: American Gene Technologies International Inc.
    Inventors: Tyler Lahusen, Mei-Ling Liou, Lingzhi Xiao, Haishan Li, Charles David Pauza
  • METHODS AND COMPOSITIONS FOR THE ACTIVATION OF TUMOR CYTOTOXICITY VIA HUMAN GAMMA-DELTA T-CELLS
    Publication number: 20200181645
    Abstract: The present disclosure relates generally to methods and compositions for activating gamma-delta (GD) T cells. Such methods and compositions can be used to treat cancer.
    Type: Application
    Filed: June 15, 2018
    Publication date: June 11, 2020
    Inventors: Charles David Pauza, Tyler Lahusen, Haishan Li, Mei-Ling Liou, Lingzhi Xiao
  • METHODS AND COMPOSITIONS FOR THE ACTIVATION OF GAMMA-DELTA T-CELLS
    Publication number: 20200063161
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Application
    Filed: September 6, 2019
    Publication date: February 27, 2020
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • METHODS AND COMPOSITIONS FOR THE ACTIVATION OF GAMMA-DELTA T-CELLS
    Publication number: 20190388456
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Application
    Filed: August 2, 2019
    Publication date: December 26, 2019
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • Methods and compositions for the activation of gamma-delta T-cells
    Patent number: 10472649
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: November 12, 2019
    Assignee: American Gene Technologies International Inc.
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • Methods and compositions for the activation of gamma-delta T-cells
    Patent number: 10428350
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: October 1, 2019
    Assignee: American Gene Technologies International Inc.
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • Methods and compositions for the activation of gamma-delta T-cells
    Patent number: 10420789
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: September 24, 2019
    Assignee: American Gene Technologies International Inc.
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • METHODS AND COMPOSITIONS FOR THE ACTIVATION OF GAMMA-DELTA T-CELLS
    Publication number: 20190083523
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Application
    Filed: September 14, 2018
    Publication date: March 21, 2019
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou
  • COMBINATION VECTORS AND METHODS FOR TREATING CANCER
    Publication number: 20190078096
    Abstract: A composition for treating cancer is disclosed. The composition includes a lentiviral particle and an aminobisphosphonate drug. The lentiviral particle is capable of infecting a target cell, such as a cancer cell, and includes an envelope protein optimized for targeting such target cell and a viral vector. The viral vector includes a small RNA optimized to target an FDPS mRNA sequence. The aminobisphosphonate drug includes zoledronic acid.
    Type: Application
    Filed: March 9, 2017
    Publication date: March 14, 2019
    Inventors: Tyler Lahusen, Mei-Ling Liou, Lingzhi Xiao, Haishan Li, Charles David Pauza
  • METHODS AND COMPOSITIONS FOR THE ACTIVATION OF GAMMA-DELTA T-CELLS
    Publication number: 20190062786
    Abstract: The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can be used in the treatment of various cancers and infectious diseases.
    Type: Application
    Filed: November 6, 2018
    Publication date: February 28, 2019
    Inventors: Charles David Pauza, Haishan Li, Tyler Lahusen, Mei-Ling Liou