Abstract: Provided is an air purifier combined with an aromatizing device, including at least one air purifying unit having a lower housing, an upper housing, a fan, a filter, a filter cover, an aromatizing device, and a bottom cover. The lower housing is a hollow housing having a lower accommodating space for receiving the filter and the aromatizing device and is provided with air inlets at circumferences thereof for allowing external air to enter the air purifying unit. The filter is a hollow and cylindrical filter body having a hollow space for filtering external air. The aromatizing device is disposed within the hollow space of the filter for aromatizing purified air from the filter to generate purified and aromatized air. The upper housing is a hollow housing having an upper accommodating space for receiving the fan and is provided with air outlets at circumferences thereof for discharging purified and aromatized air.

Abstract: This disclosure related to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.

Abstract: This disclosure related to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.

Abstract: Disclosed is an essence atomizer having an integrally formed universal connector, comprising: an atomizer universal connector integrally formed into a pipe piece, and an outer shell. Wherein, the pipe port of the first end portion is greater than the pipe port of the second end portion. On the pipe port of the first end portion is disposed inward in sequence a front connection port, the inner threads, and a bottom groove for placing a rubber ring. While on the pipe port of the second end portion is disposed an expansion ring connected to an atomizer plate, an oil prevention pad, and a nozzle cover. The essence atomizer is compact in size and simple in structure Since the essence atomizer is integrally formed into a piece, so it requires less components, and the production process can be reduced.

Abstract: Disclosed is an essence atomizer having an integrally formed universal connector, comprising: an atomizer universal connector integrally formed into a pipe piece, and an outer shell. Wherein, the pipe port of the first end portion is greater than the pipe port of the second end portion. On the pipe port of the first end portion is disposed inward in sequence a front connection port, the inner threads, and a bottom groove for placing a rubber ring. While on the pipe port of the second end portion is disposed an expansion ring connected to an atomizer plate, an oil prevention pad, and a nozzle cover. The essence atomizer is compact in size and simple in structure Since the essence atomizer is integrally formed into a piece, so it requires less components, and the production process can be reduced.

Abstract: This disclosure related to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.

Abstract: This disclosure relates to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.

Abstract: This disclosure relates to CB1 receptor antigen-binding proteins, e.g. antibodies and methods of using the CB1 receptor antibodies. The CB1 receptor antibodies may comprise an antagonistic antibody to CB1 receptors and may be used to treat various health conditions. The health conditions can comprise obesity or diabetes or any disease that benefits from antagonism of the CB1 receptor.

Abstract: The present invention provides compositions and methods relating to or derived from anti-IGF-1R antibodies. In particular embodiments, the invention provides fully human, humanized, or chimeric anti-IGF-1R antibodies that bind human IGF-1R, IGF-1R-binding fragments and derivatives of such antibodies, and IGF-1R-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having IGF-1R-related disorders or conditions.

Abstract: The present application is directed to avimers and peptides and various combinations thereof in addition to methods of making and using them.

Abstract: Described herein are variant Fc-fragments that contain an insertion within or adjacent to a loop that bind to the neonatal Fc receptor (FcRn) with higher affinity and/or higher binding activity at pH 5-6 and approximately the same or lower affinity at a physiologic pH as compared to a control Fc-fragment, that is, little or no binding activity at a physiologic pH. Also described are variant Fc-polypeptides that comprise these variant Fc-fragments. Further described are methods of making and identifying such Fc-fragments and methods for making and using such Fc-polypeptides.

Abstract: This disclosure relates to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.

Abstract: An essential oil diffuser comprises a main body and a power plug. The main body includes a shell, an electric circuit board, a connector shell, and an ultrasonic vibration module. Wherein, a receiving room is formed in the shell, an opening is formed at one end of the shell, and a shell hole is disposed on an upper shell. The connector shell is provided in the receiving room on a side of the shell opening. A receiving room is also formed in the connector shell, to receive an essence container screwed therein. The ultrasonic vibration module is disposed in the receiving room of the connector shell, and it is provided with an atomized liquid outlet corresponding to the shell hole and the connector hole, and is sleeved in the connector shell by means of a sleeve piece.

Abstract: This disclosure relates to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.

Abstract: This disclosure relates to CB1 receptor antigen-binding proteins, e.g. antibodies and methods of using the CB1 receptor antibodies. The CB1 receptor antibodies may comprise an antagonistic antibody to CB1 receptors and may be used to treat various health conditions. The health conditions can comprise obesity or diabetes or any disease that benefits from antagonism of the CB1 receptor.

Abstract: An essential oil diffuser comprises a main body and a power plug. The main body includes a shell, an electric circuit board, a connector shell, and an ultrasonic vibration module. Wherein, a receiving room is formed in the shell, an opening is formed at one end of the shell, and a shell hole is disposed on an upper shell. The connector shell is provided in the receiving room on a side of the shell opening. A receiving room is also formed in the connector shell, to receive an essence container screwed therein. The ultrasonic vibration module is disposed in the receiving room of the connector shell, and it is provided with an atomized liquid outlet corresponding to the shell hole and the connector hole, and is sleeved in the connector shell by means of a sleeve piece.

Abstract: The present application is directed to avimers and peptides and various combinations thereof in addition to methods of making and using them.

Abstract: The present invention provides compositions and methods relating to or derived from anti-IGF-1R antibodies. In particular embodiments, the invention provides fully human, humanized, or chimeric anti-IGF-1R antibodies that bind human IGF-1R, IGF-1R-binding fragments and derivatives of such antibodies, and IGF-1R-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having IGF-1R-related disorders or conditions.

Abstract: This disclosure relates to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.

Abstract: Described herein are variant Fc-fragments that contain an insertion within or adjacent to a loop that bind to the neonatal Fc receptor (FcRn) with higher affinity and/or higher binding activity at pH 5-6 and approximately the same or lower affinity at a physiologic pH as compared to a control Fc-fragment, that is, little or no binding activity at a physiologic pH. Also described are variant Fc-polypeptides that comprise these variant Fc-fragments. Further described are methods of making and identifying such Fc-fragments and methods for making and using such Fc-polypeptides.