Abstract: Devices and methods for coupling an interleaved aligned first and second secondary windings coil structure with a primary winding of a center tapped transformer are provided. In particular, a method for forming a center tapped transformer includes forming a winding core, winding a primary winding around the winding core and winding a first secondary winding and a second secondary winding in an interleaved alignment around the primary winding.

Abstract: The present disclosure relates to a flame retardant composed of multi-component phase change material particles. These particles consist of paraffin wax, nano-flame retardant, and conventional flame retardant. The phase change material is modified with nano-flame retardant and physically coated with conventional flame retardant. The multi-component phase change material flame retardant is formed by creating a two-layer nucleus-shell structure. The nucleus core is made up of the conventional flame retardant, while the shell layer is composed of the nano-flame retardant doped phase change material. The multi-component flame retardant material combines the performance advantages of phase change material, nano flame retardant, and conventional flame retardant. The combination of nano flame retardant and phase change material weakens the disadvantages of phase change material and allows for the full utilization of the energy storage capabilities of the phase change material.

Abstract: A method for preparing an MOFs flame retardant modified by layer-by-layer self-assembly of an intumescent flame retardant is provided. The method mainly includes the steps of preparing MOFs, a positive electrolyte solution, and a negative electrolyte solution; dispersing the MOFs in the negative electrolyte solution; dispersing an obtained mixture in the positive electrolyte solution; obtaining a first double-molecule self-assembled layer on surfaces of the MOFs; and repeating the above operations for several times to obtain an MOFs flame retardant modified by intumescent self-assembled layers. The modified MOFs flame retardant of the present disclosure has excellent flame retardancy, flame retardant synergism, and dispersibility, and the defects of poor dispersibility and low flame retardant efficiency of MOFs flame retardants are overcome. A great application prospect is achieved.

Abstract: The present invention provides methods for manipulating epigenetic factors to treat pediatric or juvenile osteoporosis. Specifically, the present invention provides methods for the application of H3K27 demethylase inhibitors in pediatric or juvenile subjects with osteoporosis. Thus, the present invention provides methods of administration of the H3K27 demethylase inhibitor, GSK-J4, to pediatric or juvenile subjects to effectively inhibit primary and secondary pediatric osteoporosis, especially for long-term glucocorticoid treated patients (juvenile rheumatoid disorders, Crohn's disease, nephrotic syndrome, and Duchenne muscular dystrophy) and patients who have compromised mobility (cerebral palsy, Rett syndrome, Duchenne muscular dystrophy, spina bifida, and spinal muscular atrophy).

Abstract: The present invention provides methods for manipulating epigenetic factors to treat pediatric or juvenile osteoporosis. Specifically, the present invention provides methods for the application of H3K27 demethylase inhibitors in pediatric or juvenile subjects with osteoporosis. Thus, the present invention provides methods of administration of the H3K27 demethylase inhibitor, GSK-J4, to pediatric or juvenile subjects to effectively inhibit primary and secondary pediatric osteoporosis, especially for long-term glucocorticoid treated patients (juvenile rheumatoid disorders, Crohn's disease, nephrotic syndrome, and Duchenne muscular dystrophy) and patients who have compromised mobility (cerebral palsy, Rett syndrome, Duchenne muscular dystrophy, spina bifida, and spinal muscular atrophy).

Abstract: A method for detecting electronic lighting flickering includes: taking a video of an electronic light with a duration of a predetermined period and a scanning frequency; extracting a predetermined number of frames of pictures from the video; determining a flickering frequency of the electronic light; determining at least one fixed reference point at each frame; and reconstructing a brightness waveform of the electronic light from the reference point in all frames of the video.

Abstract: A method for detecting electronic lighting flickering includes: taking a video of an electronic light with a duration of a predetermined period and a scanning frequency; extracting a predetermined number of frames of pictures from the video; determining a flickering frequency of the electronic light; determining at least one fixed reference point at each frame; and reconstructing a brightness waveform of the electronic light from the reference point in all frames of the video.

Abstract: A method for detecting electronic lighting flickering includes: taking a video of an electronic light with a duration of a predetermined period and a scanning frequency; extracting a predetermined number of frames of pictures from the video; determining a flickering frequency of the electronic light; determining at least one fixed reference point at each frame; and reconstructing a brightness waveform of the electronic light from the reference point in all frames of the video.

Abstract: A light bulb with LED symbols includes a light bulb shell, at least one LED light source, a driver, and an electrical connector. The LED light source includes electrodes and at least one LED substrate with LED chips mounted thereon. The LED substrate has a shape of a pattern, letter, word, logo, character or sign. The LED light source is housed inside a vacuum sealed chamber. The electrodes are connected to a pair of electrical wires, which are connected to a driver and an electrical connector. A method of manufacturing the light bulb is also disclosed.

Abstract: A method for detecting electronic lighting flickering includes: taking a video of an electronic light with a duration of a predetermined period and a scanning frequency; extracting a predetermined number of frames of pictures from the video; determining a flickering frequency of the electronic light; determining at least one fixed reference point at each frame; and reconstructing a brightness waveform of the electronic light from the reference point in all frames of the video.

Abstract: This invention discloses a lighting device for providing an illumination with enhanced color uniformity. The lighting device includes a light generating element adjacent a substrate and configured to produce light having wavelengths substantially within a first wavelength range; a transparent frame attached to the substrate, surrounding the transparent frame; a wavelength converting layer for converting a portion of the light produced by the light generating element into light having wavelengths within a second wavelength range, substantially covering the light emitting surface and at least part of the transparent frame; and a scattering frame configured to substantially scatter light that travels therein, covering a portion of the light emitting surface around periphery thereof to thereby receive a portion of the light leaving the wavelength converting layer around the periphery of the light emitting area. Light components in said portion of the light are substantially mixed in the scattering frame.

Abstract: This invention discloses a lighting device for providing an illumination with enhanced color uniformity. The lighting device includes a light generating element adjacent a substrate and configured to produce light having wavelengths substantially within a first wavelength range; a transparent frame attached to the substrate, surrounding the transparent frame; a wavelength converting layer for converting a portion of the light produced by the light generating element into light having wavelengths within a second wavelength range, substantially covering the light emitting surface and at least part of the transparent frame; and a scattering frame configured to substantially scatter light that travels therein, covering a portion of the light emitting surface around periphery thereof to thereby receive a portion of the light leaving the wavelength converting layer around the periphery of the light emitting area. Light components in said portion of the light are substantially mixed in the scattering frame.

Abstract: A light emitting diode package for one or more light emitting diodes mounted on a substrate. A frame is disposed on at least a portion of the substrate and substantially surrounds, but does not contact, the light emitting diode. The frame is substantially transparent to light emitted from the light emitting diode and includes one or more first wavelength converting materials. The wavelength converting materials, which may be one or more phosphors, convert at least a portion of light emitted at the emission wavelength to different wavelength. A cover covers the light emitting diode within the frame. The cover layer includes one or more second wavelength converting materials differing from the first one or more wavelength converting materials in wavelength converting material concentration or in converted light wavelength or in combinations of wavelength converting materials.

Abstract: The present invention relates to low-density lipoprotein receptor related protein 6 (LRP6). More specifically, the present invention relates to targeting of LRP6 to modulate G?s activity. In one embodiment, a method of screening for antagonists of IRP6-G?s interaction comprises the steps of (a) contacting an agent that binds LRP6 with a cell; and (b) measuring the level of cAMP production in the cell in response to one or more GPCR ligands, wherein an agent that decreases cAMP production as compared to cAMP production in the cell not contacted with the agent identifies the agent as an antagonist of LRP6-G?s interaction.

Abstract: A light emitting diode package for one or more light emitting diodes mounted on a substrate. A frame is disposed on at least a portion of the substrate and substantially surrounds, but does not contact, the light emitting diode. The frame is substantially transparent to light emitted from the light emitting diode and includes one or more first wavelength converting materials. The wavelength converting materials, which may be one or more phosphors, convert at least a portion of light emitted at the emission wavelength to different wavelength. A cover covers the light emitting diode within the frame. The cover layer includes one or more second wavelength converting materials differing from the first one or more wavelength converting materials in wavelength converting material concentration or in converted light wavelength or in combinations of wavelength converting materials.

Abstract: A light emitting device package and a lighting system are provided. According to one embodiment, a functional substrate; at least one light emitting element bonded onto the functional substrate; and at least one design-in thermal detection unit built onto the functional substrate are provided, wherein the design-in thermal detection unit is proximate to the light emitting element, and wherein the design-in thermal detection unit is configured to detect the temperature and transmit a temperature signal. The design-in thermal detection unit may be an NTC thermistor based on a semiconductor substrate. A control system may be included to detect temperature and make any necessary current adjustments in order to maintain consistent performance of the light emitting element.

Abstract: A lighting control system for controlling the lighting of a predetermined area is provided. According to one embodiment, the lighting control system comprises one or more light sources positioned in the predetermined area, the light source configured to include adjustable light intensity; a camera positioned and configured to capture an image of the predetermined area; and a controller in operable communication with the one or more light sources and the camera, the controller configured to control the one or more light sources and adjust the light intensity of the light source. The controller is configured to operate in a closed control loop to automatically adjust the lighting conditions of a predetermined area or environment. A false alarm checking process checks for temporary or localized events to prevent unnecessary lighting adjustments.

Abstract: Provided herein are methods of screening for an agent that is a PTH agonist or antagonist. For example, provided is a method of screening for an agent that is a PTH agonist or antagonist, the method comprising contacting a cell with LRP6 and the agent to be screened, wherein the cell comprises a PTH1R, and determining the level of LRP6 binding to the PTH1R. An increased level of LRP6 binding to the PTH1R compared to a control indicates the agent is a PTH agonist. A decreased level of LRP6 binding to the PTH1R compared to a control indicates the agent is a PTH antagonist. Also provided are methods of treating a skeletal disorder in a subject, wherein the skeletal disorder is characterized by proliferative bone growth or reduced bone density.

Abstract: A light emitting device with a remotely located light scattering material which improves color mixing property is provided. The light emitting device includes a substrate defining a cavity; one or more light emitting elements bonded to the substrate and positioned in the cavity; at least one first layer covering the one or more light emitting elements, at least part of the at least one first layer within the cavity, wherein the at least one first layer has a refractive index less than the refractive index of the one or more light emitting elements; and at least one second layer including light scattering material disposed on the at least one first layer, wherein the refractive index of the first layer is less than or equal to the refractive index of the second layer.

Abstract: A lighting control system for controlling the lighting of a predetermined area is provided. According to one embodiment, the lighting control system comprises one or more light sources positioned in the predetermined area, the light source configured to include adjustable light intensity; a camera positioned and configured to capture an image of the predetermined area; and a controller in operable communication with the one or more light sources and the camera, the controller configured to control the one or more light sources and adjust the light intensity of the light source. The controller is configured to operate in a closed control loop to automatically adjust the lighting conditions of a predetermined area or environment. A false alarm checking process checks for temporary or localized events to prevent unnecessary lighting adjustments.