Abstract: The present invention relates to novel pyridazin-3-yl phenol compounds of formula (I): wherein R1, R2, R3, R4 and R5 are defined herein, which inhibit NOD-like receptor protein 3 (NLRP3) inflammasome activity. The invention further relates to the processes for their preparation, pharmaceutical compositions and medicaments containing them, and their use in the treatment of diseases and disorders mediated by NLRP3.

Abstract: An electronic device that handles memory accesses includes a memory and a processor that supports a plurality of streams. The processor acquires a graph that includes paths of operations in a set of operations for processing instances of data through a model, each path of operations including a separate sequence of operations from the set of operations that is to be executed using a respective stream from among the plurality of streams. The processor then identifies concurrent paths in the graph, the concurrent paths being paths of operations between split points at which two or more paths of operations diverge and merge points at which the two or more paths of operations merge. The processor next executes operations in each of the concurrent paths using a respective stream, the executing including using memory coloring for handling memory accesses in the memory for the operations in each concurrent path.

Abstract: An electronic device that handles memory accesses includes a memory and a processor that supports a plurality of streams. The processor acquires a graph that includes paths of operations in a set of operations for processing instances of data through a model, each path of operations including a separate sequence of operations from the set of operations that is to be executed using a respective stream from among the plurality of streams. The processor then identifies concurrent paths in the graph, the concurrent paths being paths of operations between split points at which two or more paths of operations diverge and merge points at which the two or more paths of operations merge. The processor next executes operations in each of the concurrent paths using a respective stream, the executing including using memory coloring for handling memory accesses in the memory for the operations in each concurrent path.

Abstract: A method is provided to transform biomass. Non-food biomass is preprocessed. Then, fermentation is processed to generate ethanol. Ethanol is dehydrated through a catalyst to generate ethylene. After the dehydration, oligomerization is processed with a catalyst to transform ethylene into olefins having 6˜20 carbon atoms (C6˜C20). The olefins are hydrotreated into alkanes. Thus, C6˜C20 hydrocarbons having long carbon chains are formed. The hydrocarbons having 6˜10 carbon atoms can be used as gasoline; those having 8˜16 carbon atoms, jet fuel; and those having 16˜20 carbon atoms, diesel. On generating ethanol, byproducts of lignin may be generated. The byproducts can be processed through depolymerization/deoxygenation to generate aromatic hydrocarbons or can be gasified to generate methanol or dimethyl ether. By further processing dehydration, aromatic hydrocarbons are generated to be mixed into gasoline, jet fuel or diesel. Or, the lignin byproducts are gasified to generate syngas.

Abstract: A method is provided to transform biomass. Non-food biomass is preprocessed. Then, fermentation is processed to generate ethanol. Ethanol is dehydrated through a catalyst to generate ethylene. After the dehydration, oligomerization is processed with a catalyst to transform ethylene into olefins having 6˜20 carbon atoms (C6˜C20). The olefins are hydrotreated into alkanes. Thus, C6˜C20 hydrocarbons having long carbon chains are formed. The hydrocarbons having 6˜10 carbon atoms can be used as gasoline; those having 8˜16 carbon atoms, jet fuel; and those having 16˜20 carbon atoms, diesel. On generating ethanol, byproducts of lignin may be generated. The byproducts can be processed through depolymerization/deoxygenation to generate aromatic hydrocarbons or can be gasified to generate methanol or dimethyl ether. By further processing dehydration, aromatic hydrocarbons are generated to be mixed into gasoline, jet fuel or diesel. Or, the lignin byproducts are gasified to generate syngas.

Abstract: A system and method for optimization of code with non-adjacent loops. A compiler builds a node tree, which is not a control flow graph, that represents parent-child relationships of nodes of a computer program. Each node represents a control flow statement or a straight-line block of statements of the computer program. If a non-adjacent loop pair of nodes satisfy predetermined conditions, the compiler may perform legal code transformations on the computer program and corresponding node transformations on the node tree. These transformations may make adjacent this pair of loop nodes. The compiler may be configured to perform legal code transformations, such as head and tail duplication, code motion, and if-merging, in order to make adjacent these two loop nodes. Then loop fusion may be performed on this loop pair in order to increase instruction level parallelism (ILP) within an optimized version of the original source code.

Abstract: A computer-implemented method includes receiving item data at a network-based computer system, the item data related to an item categorized in at least a first category of a plurality of categories supported by the network-based computer system and including an item price-based value associated with the item. A category-specific threshold price-based value, for the first category of the plurality of categories supported by the network-based computer system, is automatically determined. The item data is automatically determined to the irregular, based on the item price-based value associated with the item and the category-specific threshold price-based value for the first category of the plurality of categories supported by the network-based computer system. Responsive to the determination that the item data is irregular, an entity associated with the item is restricted from using the network-based computer system.

Abstract: A computer-implemented method includes receiving item data at a network-based computer system, the item data related to an item categorized in at least a first category of a plurality of categories supported by the network-based computer system and including an item price-based value associated with the item. A category-specific threshold price-based value, for the first category of the plurality of categories supported by the network-based computer system, is automatically determined. The item data is automatically determined to the irregular, based on the item price-based value associated with the item and the category-specific threshold price-based value for the first category of the plurality of categories supported by the network-based computer system. Responsive to the determination that the item data is irregular, an entity associated with the item is restricted from using the network-based computer system.

Abstract: A system and method for optimization of code with non-adjacent loops. A compiler builds a node tree, which is not a control flow graph, that represents parent-child relationships of nodes of a computer program. Each node represents a control flow statement or a straight-line block of statements of the computer program. If a non-adjacent loop pair of nodes satisfy predetermined conditions, the compiler may perform legal code transformations on the computer program and corresponding node transformations on the node tree. These transformations may make adjacent this pair of loop nodes. The compiler may be configured to perform legal code transformations, such as head and tail duplication, code motion, and if-merging, in order to make adjacent these two loop nodes. Then loop fusion may be performed on this loop pair in order to increase instruction level parallelism (ILP) within an optimized version of the original source code.

Abstract: A computer-implemented method includes receiving item data at a network-based computer system, the item data related to an item categorized in at least a first category of a plurality of categories supported by the network-based computer system and including an item price-based value associated with the item. A category-specific threshold price-based value, for the first category of the plurality of categories supported by the network-based computer system, is automatically determined. The item data is automatically determined to the irregular, based on the item price-based value associated with the item and the category-specific threshold price-based value for the first category of the plurality of categories supported by the network-based computer system. Responsive to the determination that the item data is irregular, an entity associated with the item is restricted from using the network-based computer system.

Abstract: A computer-implemented method includes receiving item data at a network-based computer system, the item data related to an item categorized in at least a first category of a plurality of categories supported by the network-based computer system and including an item price-based value associated with the item. A category-specific threshold price-based value, for the first category of the plurality of categories supported by the network-based computer system, is automatically determined. The item data is automatically determined to the irregular, based on the item price-based value associated with the item and the category-specific threshold price-based value for the first category of the plurality of categories supported by the network-based computer system. Responsive to the determination that the item data is irregular, an entity associated with the item is restricted from using the network-based computer system.

Abstract: A computer-implemented method includes receiving item data at a network-based transaction facility, the item data related to an item categorized in at least a first category of a plurality of categories of the network-based transaction facility and including an item price-based value associated with the item. A category-specific threshold price-based value, for the first category of the plurality of categories of the network-based transaction facility, is automatically determined. The item data is automatically determined to the irregular, based on the item price-based value associated with the item and the category-specific threshold price-based value for the first category of the plurality of categories of the network-based transaction facility. Responsive to the determination that the item data is irregular, an electronic message is automatically communicated to an entity associated with the item.

Abstract: A computer-implemented method includes receiving item data at a network-based transaction facility, the item data related to an item categorized in at least a first category of a plurality of categories of the network-based transaction facility and including an item price-based value associated with the item. A category-specific threshold price-based value, for the first category of the plurality of categories of the network-based transaction facility, is automatically determined. The item data is automatically determined to the irregular, based on the item price-based value associated with the item and the category-specific threshold price-based value for the first category of the plurality of categories of the network-based transaction facility. Responsive to the determination that the item data is irregular, an electronic message is automatically communicated to an entity associated with the item.

Abstract: A method of filtering out item data in a report in network-based auction facilities. Data concerning multiple items is received in a database of a network-based auction facility. A price-based value is associated with at least one item. Irregular data concerning an irregular item having a price-based value greater than a predetermined price-based value is removed from a representation of the data.