Abstract: The invention provides acellular matrix from mammalian teeth for preparing a safe graft or bone replacement in regenerative medicine.

Abstract: According to some embodiments of the invention, there is provided a method of producing a bone graft, comprising: providing a tooth, converting the tooth into a plurality of particles, and selecting from available particles a subset of particles. In some embodiments, the method is performed at a dental clinic. In some embodiments, the dental bone graft is an autograft produced by grinding a patient's tooth. According to some embodiments of the invention, there is provided an apparatus configured for connecting to a motor unit to produce a bone graft at a dental clinic, comprising: a housing encasing: a chamber sized to receive a tooth, a blade assembly positioned within the chamber and configured to pulverize the tooth, an accessible compartment in which a subset of tooth particles is collected, and one or more sieves positioned to sift particles that flow between the chamber and the accessible compartment.

Abstract: According to some embodiments of the invention, there is provided a method of producing a bone graft, comprising: providing a tooth, converting the tooth into a plurality of particles, and selecting from available particles a subset of particles. In some embodiments, the method is performed at a dental clinic. In some embodiments, the dental bone graft is an autograft produced by grinding a patient's tooth. According to some embodiments of the invention, there is provided an apparatus configured for connecting to a motor unit to produce a bone graft at a dental clinic, comprising: a housing encasing: a chamber sized to receive a tooth, a blade assembly positioned within the chamber and configured to pulverize the tooth, an accessible compartment in which a subset of tooth particles is collected, and one or more sieves positioned to sift particles that flow between the chamber and the accessible compartment.