Patents by Inventor Meir Shinitzky

Meir Shinitzky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11385242
    Abstract: Provided is a composition including a combination of at least one short peptide and at least one peptide dimer, in defined ratio, to which autoantibodies found in elevated levels in schizophrenic patients bind.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: July 12, 2022
    Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Meir Shinitzky, Ludmila Schechtman
  • Patent number: 11262364
    Abstract: Provided is a composition including a combination of at least one short peptide and at least one peptide dimer, in defined ratio, to which autoantibodies found in elevated levels in schizophrenic patients bind.
    Type: Grant
    Filed: July 14, 2016
    Date of Patent: March 1, 2022
    Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Meir Shinitzky, Ludmila Schechtman
  • Publication number: 20180348234
    Abstract: Provided is a composition including a combination of at least one short peptide and at least one peptide dimer, in defined ratio, to which autoantibodies found in elevated levels in schizophrenic patients bind.
    Type: Application
    Filed: July 14, 2016
    Publication date: December 6, 2018
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Meir SHINITZKY, Ludmila SCHECHTMAN
  • Publication number: 20150157588
    Abstract: The present invention relates to the compound amino-phenyl-acetic acid octadec-(Z)-9-enyl ester, an enantiomer thereof or a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising it, for use in the treatment of tumors and metastases, and to methods for treating a tumor or metastases comprising administering said compound to a subject in need thereof. The present invention particularly relates to said compound when it is dissolved in an ethanol solution.
    Type: Application
    Filed: July 4, 2013
    Publication date: June 11, 2015
    Inventors: Irun R. Cohen, Meir Shinitzky, Raanan Margalit, Michal Cohen-Sfady, Alexandra Zanin-Zhorov
  • Patent number: 8987263
    Abstract: Basic esters of fatty alcohols of the general formula: R1-O—CO-A or pharmaceutically acceptable salts thereof, wherein R1 is C12-C24 alkyl or C10-C24 alkenyl, and A is a residue containing at least one acyclic or cyclic amino group and/or at least one heteroaromatic ring containing a tertiary or quaternary nitrogen atom, are anti-inflammatory and immunomodulatory agents, useful in the treatment of immunologically-mediated inflammation, as adjuvants for antigens involved in both cellular and humoral responses.
    Type: Grant
    Filed: October 9, 2003
    Date of Patent: March 24, 2015
    Inventors: Meir Shinitzky, Irun R. Cohen, Raanan Margalit, Yaacov Herzig, Jeffrey Sterling, Gyorgy Toth, Istvan Miskolczi, Ferenc Rantal, Tivadar Tamas
  • Patent number: 8101552
    Abstract: The invention pertains to the use of six-membered cyclic phosphates as plant growth regulators and methods for regulating the growth of plants using such compounds.
    Type: Grant
    Filed: March 14, 2006
    Date of Patent: January 24, 2012
    Assignees: Yeda Research and Development Company Ltd., Ben Gurion University of the Negev Research and Development Authority
    Inventors: Meir Shinitzky, Dan Pelah, David Mills, Hanna Mills, legal representative, Avishay Pelah
  • Publication number: 20110280918
    Abstract: A paste composition comprising at least 25% phospholipids by weight in combination with at least 0.5% ascorbic acid by weight and a cosmetic product comprising this paste and a cosmetically acceptable carrier.
    Type: Application
    Filed: October 23, 2008
    Publication date: November 17, 2011
    Applicant: L. RAPHAEL SA
    Inventor: Meir Shinitzky
  • Publication number: 20090170701
    Abstract: The invention pertains to the use of six-membered cyclic phosphates as plant growth regulators and methods for regulating the growth of plants using such compounds.
    Type: Application
    Filed: March 14, 2006
    Publication date: July 2, 2009
    Inventors: Meir Shinitzky, Dan Pelah, David Mills, Avishay Pelah
  • Patent number: 7098304
    Abstract: The invention concerns peptides which bind antibodies that are found in elevated levels in body fluids of schizophrenic patients and are found at a lower level or not found at all in body fluids of non-schizophrenic individuals. Using a computerized program, the antigenic epitope of the peptides of the invention is predicted as having a core of hydrophobic amino acids which is surrounded by positively charged amino acids. The peptides of the invention are useful in the diagnosis of schizophrenia in an individual.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: August 29, 2006
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Meir Shinitzky, Michael Deckmann
  • Publication number: 20060183797
    Abstract: Immunomodulators selected from: (a) a saturated or cis-unsaturated C10-C20 fatty alcohol or an ester thereof with a C1-C6 alkanoic acid; (b) a monoester of a C2-C8 alkanediol or of Glycerol with a saturated or cis-unsaturated C10-C20 fatty acid; and (c) a diester of glycerol with a saturated or cis-unsaturated C10-C20 fatty acid, are useful for treatment of inflammation, particularly immunologically-mediated inflammation such as it occurs in autoimmune diseases.
    Type: Application
    Filed: April 11, 2002
    Publication date: August 17, 2006
    Inventors: Irun Cohen, Meir Shinitzky, Raanan Margalit
  • Publication number: 20060173053
    Abstract: Basic esters of fatty alcohols of the general formula: R1-O—CO-A or pharmaceutically acceptable salts thereof, wherein R1 is C12-C24 alkyl or C10-C24 alkenyl, and A is a residue containing at least one acyclic or cyclic amino group and/or at least one heteroaromatic ring containing a tertiary or quaternary nitrogen atom, are anti-inflammatory and immunomodulatory agents, useful in the treatment of immunologically-mediated inflammation, as adjuvants for antigens involved in both cellular and humoral responses.
    Type: Application
    Filed: December 19, 2005
    Publication date: August 3, 2006
    Inventors: Meir Shinitzky, Irun Cohen, Raanan Margalit, Yaacov Herzig, Jeffrey Sterling, Gyorgy Toth, Istvan Miskolczi, Ferenc Rantal, Tivadar Tamas
  • Patent number: 7070760
    Abstract: A diagnostic method for assaying schizophrenia in a subject is provided wherein a preparation comprising platelet derived proteins or fractions thereof having a pI above about 6.5 is injected into a subject and the occurrence of delayed type hypersensitivity (DTH) reaction at the site of the injection is determined. A positive DTH reaction indicates that the tested subject has a high likelihood of being schizophrenic. The protein preparation used in the diagnostic method is also provided as well as a method for its preparation and a kit for use in the diagnosis of schizophrenia using the above method.
    Type: Grant
    Filed: December 7, 1998
    Date of Patent: July 4, 2006
    Assignee: Yeda Research and Development Co., Ltd.
    Inventors: Meir Shinitzky, Michael Deckmann
  • Publication number: 20060040901
    Abstract: The present invention discloses new cyclic glycerophosphates and cyclic popandiol phosphates and pharmaceutical compositions comprising said compounds for promoting neural activity such as neuronal outgrowth, nerve growth, prevention of nerve degeneration and nerve rescue.
    Type: Application
    Filed: March 13, 2003
    Publication date: February 23, 2006
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. Ltd.
    Inventor: Meir Shinitzky
  • Publication number: 20060014726
    Abstract: The present invention discloses new cyclic glycerophosphates and cyclic popandiol phosphates and pharmaceutical compositions comprising said compounds for stimulation of target cells. In particular, enhancing expressions of various proteins within the cell. Such enhancement is used in differentiation therapy.
    Type: Application
    Filed: March 13, 2003
    Publication date: January 19, 2006
    Inventors: Meir Shinitzky, Rachel Haimovitz
  • Publication number: 20050169955
    Abstract: The invention relates to a method for attracting flying insects, particularly mosquitoes, for the purpose of trapping or killing them, which comprises releasing at least one chemical attractant for the insects including carbon dioxide, by reacting with water or other aqueous medium, a mixture of ingredients (such as sugar and yeast) which has previously been maintained in a substantially oxygen-free environment and which have the ability to interact with each other in presence of water or other aqueous medium, so as to generate the at least one chemical attractant. The invention also includes an essentially air-proof sealed package containing a mixture, substantially free of contact with oxygen, of the type described; the mixture also constitutes per se, an aspect of the invention.
    Type: Application
    Filed: February 4, 2004
    Publication date: August 4, 2005
    Inventors: Miriam Simchoni Barak, Meir Shinitzky, Gunter Muller
  • Patent number: 6914056
    Abstract: Cyclic glycerophosphates and analogs thereof (CGs) are shown to exert neutral promoting activities in target cells. Such activities include promotion of neuronal outgrowth, promotion of nerve growth, provision of dopaminotrophic supporting envrionment in a diseased portion of the brain, prevention of nerve degeneration and nerve rescue. These activities of the CGs render them useful for treatment of various disorders including but not limited to mental disorders such as, for example, schizophrenia, dementia or disorders resulting in learning disablities. In addition, these CGs may be used for the treatment of neurodegenerative conditions such as Altzheimer's diesease, Parkinson's disease, conditions resulting from exposure to harmful environmental factors or resulting from a mechanical injury. The CGs may also be used to treat an individual suffering from a primary neurodengenerative condition in order to prevent or reduce the appearance of secondary degeneration in additional nerves (“nerve rescue”).
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: July 5, 2005
    Assignee: Yeda Research and Development Co., Ltd.
    Inventor: Meir Shinitzky
  • Patent number: 6872712
    Abstract: Cyclic glycerophosphates as well as some analogs thereof (CGs) are shown to increase phosphorylation of intracellular proteins in various cells. Such activity is not found with linear ? or ? glycerophosphates. The phosphorylating activity of the CGs render them useful in the prevention and treatment of various disorders and diseases such as, for example, different kinds of malignancies as well as disorders involving hormone and hormone-like signaling. The CGs are also useful for promotion of target cell differentiation and for detection of abnormal conditions in target cells.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: March 29, 2005
    Assignee: Yeda Research and Development Co. Ltd.
    Inventor: Meir Shinitzky
  • Publication number: 20040247604
    Abstract: Therapeutic preparations are provided for treatment of a T-cell mediated disease or condition comprising an antigen and a carrier, wherein said antigen is an antigen recognized by inflammatory T cells associated with the pathogenesis of said T-cell mediated disease or condition, and wherein said carrier is an anti-inflammatory immunomodulator selected from: (a) a saturated or cis-unsaturated C10-C20 fatty alcohol or an ester thereof with a C1-C6 alkanoic acid; and (b) a saturated or cis-unsaturated C10-C20 fatty acid ester selected from a C1-C6 alkyl ester, a monoester with a C2-C6 polyol having a least two hydroxy groups, and a diester with glycerol.
    Type: Application
    Filed: July 29, 2004
    Publication date: December 9, 2004
    Inventors: Irun R. Cohen, Meir Shinitzky, Raanan Margalit
  • Publication number: 20040025412
    Abstract: A device and method for trapping flying insects including a housing having an opening for the entry of insects; a physical attractant for the insects; a trapping arrangement arranged in association with the physical attractant for trapping insects attracted thereto; and an emission arrangement for emitting a chemical attractant for the insects employing a cartridge which contains predetermined amounts of preselected chemical reactants and which engages the trapping device so that the cartridge is operative to enable the emission arrangement to produce a gaseous suspension of the chemical attractant in the vicinity of the trapping device.
    Type: Application
    Filed: February 4, 2003
    Publication date: February 12, 2004
    Inventors: Miriam Simchoni, Meir Shinitzky
  • Publication number: 20030190323
    Abstract: The present invention provides pharmaceutical compositions and methods for reducing the incidence or severity of insulin dependent diabetes mellitus, insulitis, &bgr;-cell destruction, or latent autoimmune diabetes in adults by administering to a patient a pharmaceutical composition comprising an antigen and a carrier, wherein the antigen is recognized by inflammatory T cells associated with the pathogenesis of the disease and the carrier is a metabolizable lipid emulsion. The composition induces a TH1→TH2 shift in the cytokines produced by said T cells and it is administered in an amount, which is therapeutically effective to reduce the symptoms of the disease.
    Type: Application
    Filed: December 2, 2002
    Publication date: October 9, 2003
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Irun R. Cohen, Dana Elias, Meir Shinitzky