Patents by Inventor Meital Zilberman
Meital Zilberman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190262276Abstract: A bioadhesive formulation, comprising gelatin, alginate and a coupling agent, capable of forming a bioadhesive matrix, which is characterized by rapid curing, optimal viscosity, high bonding strength, flexibility, biocompatibility and biodegradability, is disclosed. Further disclosed is such a bioadhesive formulation which further comprises a bioactive agent, and a drug-eluting bioadhesive matrix formed therefrom, the bioadhesive matrix being capable of delivering the bioactive agent to a bodily site. Methods utilizing the bioadhesive formulations and matrices in various biological and medical procedures are also disclosed.Type: ApplicationFiled: March 6, 2019Publication date: August 29, 2019Applicant: Active Healing Biomedical Ltd.Inventors: Meital Zilberman, Adaya Shefy-Peleg, Binyamin Cohen, Maytal Foox
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Patent number: 10265274Abstract: A bioadhesive formulation, comprising gelatin, alginate and a coupling agent, capable of forming a bioadhesive matrix, which is characterized by rapid curing, optimal viscosity, high bonding strength, flexibility, biocompatibility and biodegradability, is disclosed. Further disclosed is such a bioadhesive formulation which further comprises a bioactive agent, and a drug-eluting bioadhesive matrix formed therefrom, the bioadhesive matrix being capable of delivering the bioactive agent to a bodily site. Methods utilizing the bioadhesive formulations and matrices in various biological and medical procedures are also disclosed.Type: GrantFiled: December 4, 2017Date of Patent: April 23, 2019Assignee: Active Healing Biomedical Ltd.Inventors: Meital Zilberman, Adaya Shefy-Peleg, Binyamin Cohen, Maytal Foox
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Publication number: 20190083676Abstract: A kit and a bioadhesive, comprising gelatin, alginate, montmorillonite and a coupling agent, which is characterized by rapid curing, optimal viscosity, high burst strength, flexibility, biocompatibility and biodegradability, is disclosed.Type: ApplicationFiled: October 20, 2016Publication date: March 21, 2019Inventors: Meital ZILBERMAN, Oded PINKAS
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Publication number: 20180133164Abstract: A bioadhesive formulation, comprising gelatin, alginate and a coupling agent, capable of forming a bioadhesive matrix, which is characterized by rapid curing, optimal viscosity, high bonding strength, flexibility, biocompatibility and biodegradability, is disclosed. Further disclosed is such a bioadhesive formulation which further comprises a bioactive agent, and a drug-eluting bioadhesive matrix formed therefrom, the bioadhesive matrix being capable of delivering the bioactive agent to a bodily site. Methods utilizing the bioadhesive formulations and matrices in various biological and medical procedures are also disclosed.Type: ApplicationFiled: December 4, 2017Publication date: May 17, 2018Applicant: Technology Innovation Momentum Fund (Israel) Limited PartnershipInventors: Meital Zilberman, Adaya Shefy-Peleg, Binyamin Cohen, Maytal Foox
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Publication number: 20180133149Abstract: Composite structures composed of a fibril core and a polymeric coat and designed capable of encapsulating both hydrophobic and hydrophilic bioactive agents while retaining the activity of these agents are disclosed. Further disclosed are processes of preparing such composite structures, and medical devices and disposable articles made therefrom.Type: ApplicationFiled: December 11, 2017Publication date: May 17, 2018Inventor: Meital Zilberman
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Patent number: 9877926Abstract: A bioadhesive formulation, comprising gelatin, alginate and a coupling agent, capable of forming a bioadhesive matrix, which is characterized by rapid curing, optimal viscosity, high bonding strength, flexibility, biocompatibility and biodegradability, is disclosed. Further disclosed is such a bioadhesive formulation which further comprises a bioactive agent, and a drug-eluting bioadhesive matrix formed therefrom, the bioadhesive matrix being capable of delivering the bioactive agent to a bodily site. Methods utilizing the bioadhesive formulations and matrices in various biological and medical procedures are also disclosed.Type: GrantFiled: February 14, 2013Date of Patent: January 30, 2018Assignee: Technology Innovation Momentum Fund (Israel) Limited PartnershipInventors: Meital Zilberman, Adaya Shefy-Peleg, Binyamin Cohen, Maytal Foox
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Publication number: 20170065519Abstract: Composite structures composed of a fibril core and a polymeric coat and designed capable of encapsulating both hydrophobic and hydrophilic bioactive agents while retaining the activity of these agents are disclosed. Further disclosed are processes of preparing such composite structures, and medical devices and disposable articles made therefrom.Type: ApplicationFiled: August 11, 2016Publication date: March 9, 2017Applicant: Ramot at Tel-Aviv University Ltd.Inventor: Meital ZILBERMAN
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Patent number: 9446226Abstract: Composite structures composed of a fibril core and a polymeric coat and designed capable of encapsulating both hydrophobic and hydrophilic bioactive agents while retaining the activity of these agents are disclosed. Further disclosed are processes of preparing such composite structures, and medical devices and disposable articles made therefrom.Type: GrantFiled: December 7, 2006Date of Patent: September 20, 2016Assignee: Ramot at Tel-Aviv University Ltd.Inventor: Meital Zilberman
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Publication number: 20160082161Abstract: Composite structures composed of a device as a core structure, being a medical device or article, and a porous polymeric coat and designed capable of encapsulating bioactive agents while retaining the activity of these agents are disclosed. Further disclosed are processes of preparing such composite structures.Type: ApplicationFiled: December 3, 2015Publication date: March 24, 2016Applicant: Ramot at Tel-Aviv University Ltd.Inventors: Meital ZILBERMAN, Yoel KLOOG, Amir KRAITZER, Jonathan ELSNER
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Publication number: 20150038424Abstract: A bioadhesive formulation, comprising gelatin, alginate and a coupling agent, capable of forming a bioadhesive matrix, which is characterized by rapid curing, optimal viscosity, high bonding strength, flexibility, biocompatibility and biodegradability, is disclosed. Further disclosed is such a bioadhesive formulation which further comprises a bioactive agent, and a drug-eluting bioadhesive matrix formed therefrom, the bioadhesive matrix being capable of delivering the bioactive agent to a bodily site. Methods utilizing the bioadhesive formulations and matrices in various biological and medical procedures are also disclosed.Type: ApplicationFiled: February 14, 2013Publication date: February 5, 2015Inventors: Meital Zilberman, Adaya Shefy-Peleg, Binyamin Cohen, Maytal Foox
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Patent number: 8697117Abstract: Polymeric porous films, capable of eluding a bioactive agent when coming in contact with a physiological medium according to a pre-determined and controlled release profile suitable for particular type of drug and indication, and medical devices including the same are disclosed. Also disclosed are processes for producing the polymeric porous films by freeze-drying an inverted emulsion formulation in which the polymer's composition, the polymer's concentration, the polymer's initial molecular weight, the concentration and/or the type of a surfactant, the homogenization rate and/or the oil phase to aqueous phase ratio (O:A) are selected so as to impart a desired release profile of the bioactive agent from the polymeric film.Type: GrantFiled: August 2, 2011Date of Patent: April 15, 2014Assignee: Ramot at Tel-Aviv University Ltd.Inventor: Meital Zilberman
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Publication number: 20120027833Abstract: Polymeric porous films, capable of eluding a bioactive agent when coming in contact with a physiological medium according to a pre-determined and controlled release profile suitable for particular type of drug and indication, and medical devices including the same are disclosed. Also disclosed are processes for producing the polymeric porous films by freeze-drying an inverted emulsion formulation in which the polymer's composition, the polymer's concentration, the polymer's initial molecular weight, the concentration and/or the type of a surfactant, the homogenization rate and/or the oil phase to aqueous phase ratio (O:A) are selected so as to impart a desired release profile of the bioactive agent from the polymeric film.Type: ApplicationFiled: August 2, 2011Publication date: February 2, 2012Applicant: Ramot at Tel-Aviv University Ltd.Inventor: Meital ZILBERMAN
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Publication number: 20110091515Abstract: Composite structures composed of a device as a core structure, being a medical device or article, and a porous polymeric coat and designed capable of encapsulating bioactive agents while retaining the activity of these agents are disclosed. Further disclosed are processes of preparing such composite structures.Type: ApplicationFiled: June 11, 2009Publication date: April 21, 2011Applicant: Ramot at Tel-Aviv University Ltd.Inventors: Meital Zilberman, Yoel Kloog, Amir Kraitzer, Jonathan Elsner
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Publication number: 20070134305Abstract: Composite structures composed of a fibril core and a polymeric coat and designed capable of encapsulating both hydrophobic and hydrophilic bioactive agents while retaining the activity of these agents are disclosed. Further disclosed are processes of preparing such composite structures, and medical devices and disposable articles made therefrom.Type: ApplicationFiled: December 7, 2006Publication date: June 14, 2007Applicant: Ramot At Tel Aviv University Ltd.Inventor: Meital Zilberman
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Publication number: 20030050687Abstract: The present invention is a structural support stent for use in a body lumen made up of a self-expanding biocompatible material that forms a cylinder having an inner surface and an outer surface. Advantages of the present invention include its self-expanding nature and ease of manufacturing. The present invention also has an ability to deliver drugs in a time-released fashion.Type: ApplicationFiled: July 3, 2001Publication date: March 13, 2003Inventors: Nathan D. Schwade, Meital Zilberman