Patents by Inventor Meizheng Liu

Meizheng Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090043111
    Abstract: A method for producing compounds of the formula: Wherein R2 is selected from the group consisting of amino, lower alkylamino, di-lower alkylamino, allylamino, diallylamino, N-lower alkyl-N-allylamino, benzylamino, dibenzylamino, phenethylamino, diphenethylamino, 4-hydroxyphenethylamino or di-(4-hydroxyphenethylamino); comprising: a) reacting with Wittig Reagent to produce wherein R1 is alkoxyl; f) hydrolyzing compound II under acidic conditions to produce g) subjecting compound III to reduction and amination to produce the tertiary amine wherein R2 is as defined above; h) reacting compound IV with 4-chlorophenoxyacetonitrile to create nucleophilic substitution to produce the nitrile compound wherein R2 is as defined above; and i) effecting reduction and hydrolysis in the same step with palladium/C and sodium hydroxide to produce wherein R2 is as defined above.
    Type: Application
    Filed: August 6, 2007
    Publication date: February 12, 2009
    Inventor: Meizheng Liu