Patents by Inventor Mekhine J. Baccam

Mekhine J. Baccam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacterial inosine 5?-monophosphate dehydrogenase (“IMPDH”) DNA as a dominant selectable marker in mammals and other eukaryotes
    Patent number: 7183106
    Abstract: The present invention relates to a nucleic acid sequence and its corresponding protein sequence useful as a dominant selectable marker in eukaryotes. More specifically the invention relates to a nucleic acid encoding a bacterial IMPDH gene that has been engineered into a eukaryotic expression vectors, thereby permitting bacterial IMPDH expression in mammalian cells. Bacterial IMPDH expression confers resistance to MPA which can be used as dominant selectable marker in eukaryotes including mammals. The invention also relates to expression vectors and cells that express the bacterial IMPDH gene as well as gene therapies and protein synthesis.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: February 27, 2007
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Eliezer Huberman, Mekhine J. Baccam