Patents by Inventor Mekonnen DEMEKE

Mekonnen DEMEKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Xylose isomerases that confer efficient xylose fermentation capability to yeast
    Patent number: 11692187
    Abstract: The present invention relates to novel nucleic acid sequences encoding bacterial xylose isomerases that upon transformation of a eukaryotic microbial host cell, such as yeast, to confer to the host cell the ability of isomerising xylose to xylulose. The nucleic acid sequences encode xylose isomerases that originate from bacteria such as Eubacterium sp., Clostridium cellulosi and others. The invention further relates to fermentation processes wherein the transformed host cells ferment a xylose-containing medium to produce ethanol or other fermentation products.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: July 4, 2023
    Assignees: VIB vzw, Katholieke Universiteit Leuven, K.U. Leuven R&D, GlobalYeast N.V.
    Inventors: Johan Thevelein, Mekonnen Demeke, Maria Remedios Foulquié Moreno, Stijn De Graeve, Edgard Valdomiro Charles Belo
  • Xylose Isomerases that confer efficient xylose fermentation capability to yeast
    Publication number: 20190316111
    Abstract: The present invention relates to novel nucleic acid sequences encoding bacterial xylose isomerases that upon transformation of a eukaryotic microbial host cell, such as yeast, to confer to the host cell the ability of isomerising xylose to xylulose. The nucleic acid sequences encode xylose isomerases that originate from bacteria such as Eubacterium sp., Clostridium cellulosi and others. The invention further relates to fermentation processes wherein the transformed host cells ferment a xylose-containing medium to produce ethanol or other fermentation products.
    Type: Application
    Filed: December 21, 2017
    Publication date: October 17, 2019
    Applicants: VIB vzw, Katholieke Universiteit Leuven, K.U. Leuven R&D, GlobalYeast N.V.
    Inventors: Johan Thevelein, Mekonnen Demeke, Maria Remedios Foulquié Moreno, Stijn De Graeve, Edgard Valdomiro Charles Belo
  • Mutant NNK1 allele and its use
    Patent number: 9809830
    Abstract: The present invention relates to a mutant NNK1 allele, especially a mutant carrying a mutation at position of amino acid 807 of the wild type sequence. The invention relates further to the use of said mutant allele to increase the fermentation rate in yeast, preferably in Saccharomyces. The mutant allele is especially useful to increase the xylose to ethanol fermentation rate.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: November 7, 2017
    Assignees: VIB VZW, KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D
    Inventors: Johan Thevelein, Mekonnen Demeke, Maria Remedios Foulquié Moreno
  • MUTANT NNK1 ALLELE AND ITS USE
    Publication number: 20160312244
    Abstract: The present invention relates to a mutant NNK1 allele, especially a mutant carrying a mutation at position of amino acid 807 of the wild type sequence. The invention relates further to the use of said mutant allele to increase the fermentation rate in yeast, preferably in Saccharomyces. The mutant allele is especially useful to increase the xylose to ethanol fermentation rate.
    Type: Application
    Filed: December 12, 2014
    Publication date: October 27, 2016
    Inventors: Johan Thevelein, Mekonnen DEMEKE, Maria Remedios Foulquié Moreno