Patents by Inventor Melanie Boze

Melanie Boze has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ABCA1 elevating compounds
    Patent number: 7579504
    Abstract: The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: August 25, 2009
    Assignee: Gilead Sciences, Inc.
    Inventors: Dmitry Koltun, Melanie Boze, Jeff Zablocki
  • 3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS
    Publication number: 20090105283
    Abstract: The present invention discloses 3-hydroquinazolin-4-one derivatives for use as inhibitors of stearoyl-CoA desaturase. The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cancer, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.
    Type: Application
    Filed: October 15, 2008
    Publication date: April 23, 2009
    Inventors: Dmitry Koltun, Eric Parkhill, Melanie Boze, Jeff Zablocki, Natalya Vasilevich, Elena Mayboroda, Andrei Glushkov, Andrew G. Cole, Jeffrey Chisholm
  • 3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS
    Publication number: 20080255161
    Abstract: The present invention discloses 3-hydroquinazolin-4-one derivatives for use as inhibitors of stearoyl-CoA desaturase. The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cancer, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.
    Type: Application
    Filed: April 9, 2008
    Publication date: October 16, 2008
    Inventors: Dmitry Koltun, Eric Parkhill, Melanie Boze, Jeff Zablocki, Natalya Vasilevich, Elena Mayboroda, Andrei Glushkov, Andrew Cole, Jeffrey Chisholm
  • ABCA1 elevating compounds
    Patent number: 7432276
    Abstract: The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.
    Type: Grant
    Filed: December 27, 2006
    Date of Patent: October 7, 2008
    Assignee: CV Therapeutics, Inc.
    Inventors: Matthew Abelman, Robert Jiang, Jeff Zablocki, Dmitry Koltun, Melanie Boze
  • ABCA1 elevating compounds
    Publication number: 20070203245
    Abstract: The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.
    Type: Application
    Filed: December 7, 2006
    Publication date: August 30, 2007
    Inventors: Dmitry Koltun, Melanie Boze, Jeff Zablocki
  • ABCA1 elevating compounds
    Publication number: 20070191379
    Abstract: The present invention provides compounds useful for increasing cellular ATP binding cassette transporter ABCA1 production in mammals, and to methods of using such compounds in the treatment of coronary artery diseases, dyslipidiemias and metabolic syndrome. The invention also relates to methods for the preparation of such compounds, and to pharmaceutical compositions containing them.
    Type: Application
    Filed: December 27, 2006
    Publication date: August 16, 2007
    Inventors: Matthew Abelman, Robert Jiang, Jeff Zablocki, Dmitry Koltun, Melanie Boze