Patents by Inventor Melanie Cobb

Melanie Cobb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isoxazole treatments for diabetes
    Patent number: 9221800
    Abstract: The present invention relates to compounds and methods for inducing synthesis and secretion of insulin from pancreatic beta cells. The methods may take place in vitro, ex vivo such as in isolates from adult mammalian tissue, or in vivo. Compounds and methods described herein may find use in the treatment of diabetes.
    Type: Grant
    Filed: April 10, 2014
    Date of Patent: December 29, 2015
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Elhadji Dioum, Jay Schneider, Doug Frantz, Hector Aguilar, Melanie Cobb
  • Isoxazole Treatments for Diabetes
    Publication number: 20140315966
    Abstract: The present invention relates to compounds and methods for inducing synthesis and secretion of insulin from pancreatic beta cells. The methods may take place in vitro, ex vivo such as in isolates from adult mammalian tissue, or in vivo. Compounds and methods described herein may find use in the treatment of diabetes.
    Type: Application
    Filed: April 10, 2014
    Publication date: October 23, 2014
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Elhadji DIOUM, Jay SCHNEIDER, Doug FRANTZ, Hector AGUILAR, Melanie COBB
  • Isoxazole treatments for diabetes
    Patent number: 8722716
    Abstract: The present invention relates to compounds and methods for inducing synthesis and secretion of insulin from pancreatic beta cells. The methods may take place in vitro, ex vivo such as in isolates from adult mammalian tissue, or in vivo. Compounds and methods described herein may find use in the treatment of diabetes.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: May 13, 2014
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Elhadij Dioum, Jay Schneider, Doug Frantz, Hector Aguilar, Melanie Cobb
  • TAO protein kinase polypeptides and methods of use therefor
    Patent number: 7078182
    Abstract: Compositions and methods are provided for potentiating the activity of the mitogen-activated protein kinase p38. In particular the mitogen-activated protein kinase kinase MEK6, and variants thereof that stimulate phosphorylation of p38 are provided. Such compounds may be used, for example, for therapy of diseases associated with the p38 cascade and to identify antibodies and other agents that inhibit or activate signal transduction via p38.
    Type: Grant
    Filed: October 10, 2000
    Date of Patent: July 18, 2006
    Assignee: Board of Regents, The University of Texas System
    Inventors: Melanie Cobb, Michelle Hutchinson, Zhu Chen, Kevin Berman
  • Tao protein kinases and methods of use therefor
    Patent number: 6165461
    Abstract: Compositions and methods are provided for potentiating the activity of the mitogen-activated protein kinase p38. In particular the mitogen-activated protein kinase kinase MEK6, and variants thereof that stimulate phosphorylation of p38 are provided. Such compounds may be used, for example, for therapy of diseases associated with the p38 cascade and to identify antibodies and other agents that inhibit or activate signal transduction via p38.
    Type: Grant
    Filed: April 14, 1998
    Date of Patent: December 26, 2000
    Assignee: Board of Regents, University of Texas System
    Inventors: Melanie Cobb, Michele Hutchison, Zhu Chen, Kevin Berman