Patents by Inventor MELANIE DIEFENBACHER

MELANIE DIEFENBACHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of xylitol from glucose by a recombinant strain
    Patent number: 10829742
    Abstract: The present invention relates to a recombinant microbial host for the production of xylitol, the recombinant microbial host containing a nucleic acid sequence encoding a NAD+-specific D-arabitol 4-oxidoreductase (EC 1.1.1.11) using D-arabitol as substrate and producing D-xylulose as product, and a nucleic acid sequence encoding a NADPH-specific xylitol dehydrogenase using D-xylulose as substrate and producing xylitol as product.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: November 10, 2020
    Assignee: ROQUETTE FRERES
    Inventors: Astrid Schaefer, Melanie Diefenbacher, Yiming Chang, Sumire Honda Malca, Markus Schwab, Sophie Defretin, Tania Gerard, Arnaud Heysen, Friederike Thor
  • PRODUCTION OF XYLITOL FROM GLUCOSE BY A RECOMBINANT STRAIN
    Publication number: 20200032224
    Abstract: The present invention relates to a recombinant microbial host for the production of xylitol, the recombinant microbial host containing a nucleic acid sequence encoding a NAD+-specific D-arabitol 4-oxidoreductase (EC 1.1.1.11) using D-arabitol as substrate and producing D-xylulose as product, and a nucleic acid sequence encoding a NADPH-specific xylitol dehydrogenase using D-xylulose as substrate and producing xylitol as product.
    Type: Application
    Filed: September 13, 2019
    Publication date: January 30, 2020
    Applicant: ROQUETTE FRERES
    Inventors: Astrid SCHAEFER, Melanie DIEFENBACHER, Yiming CHANG, Sumire HONDA MALCA, Markus SCHWAB, Sophie DEFRETIN, Tania GERARD, Arnaud HEYSEN, Friederike THOR
  • Production of xylitol from glucose by a recombinant strain
    Patent number: 10494614
    Abstract: The present invention relates to a recombinant microbial host for the production of xylitol, the recombinant microbial host containing a nucleic acid sequence encoding an NAD+-specific D-arabitol 4-oxidoreductase (EC 1.1.1.11) using D-arabitol as substrate and producing D-xylulose as product, and a nucleic acid sequence encoding an NADPH-specific xylitol dehydrogenase using D-xylulose as substrate and producing xylitol as product.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: December 3, 2019
    Assignee: ROQUETTE FRERES
    Inventors: Astrid Schaefer, Melanie Diefenbacher, Yiming Chang, Sumire Honda Malca, Markus Schwab, Sophie Defretin, Tania Gerard, Arnaud Heysen, Friederike Thor
  • PRODUCTION OF XYLITOL FROM GLUCOSE BY A RECOMBINANT STRAIN
    Publication number: 20170130209
    Abstract: The present invention relates to a recombinant microbial host for the production of xylitol, the recombinant microbial host containing a nucleic acid sequence encoding an NAD+-specific D-arabitol 4-oxidoreductase (EC 1.1.1.11) using D-arabitol as substrate and producing D-xylulose as product, and a nucleic acid sequence encoding an NADPH-specific xylitol dehydrogenase using D-xylulose as substrate and producing xylitol as product.
    Type: Application
    Filed: June 17, 2015
    Publication date: May 11, 2017
    Inventors: ASTRID SCHAEFER, MELANIE DIEFENBACHER, YIMING CHANG, SUMIRE HONDA MALCA, MARKUS SCHWAB, SOPHIE DEFRETIN, TANIA GERARD, ARNAUD HEYSEN, FRIEDERIKE THOR