Patents by Inventor Melanie FISCHER

Melanie FISCHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-A2AP ANTIBODIES AND USES THEREOF
    Publication number: 20240034810
    Abstract: The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.
    Type: Application
    Filed: June 6, 2023
    Publication date: February 1, 2024
    Inventors: Stefan HEITMEIER, Julia Glunz, Melanie Fischer, Cindy Schulenburg, Hannah Jörissen, Christoph Thiel, Andreas Wilmen, Ernst Weber
  • NOVEL ANTI-A2AP ANTIBODIES AND USES THEREOF
    Publication number: 20240010750
    Abstract: The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.
    Type: Application
    Filed: September 13, 2021
    Publication date: January 11, 2024
    Inventors: Stefan HEITMEIER, Julia GLUNZ, Melanie FISCHER, Cindy SCHULENBURG, Hannah JÖRISSEN, Christoph THIEL, Andreas WILMEN, Ernst WEBER
  • ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-B7H3-ANTIBODIES
    Publication number: 20180185510
    Abstract: The present application relates to novel binder drug conjugates (ADCs), to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for the treatment and/or prophylaxis of diseases and to the use of these ADCs for preparing medicaments for treatment and/or prophylaxis of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures.
    Type: Application
    Filed: June 20, 2016
    Publication date: July 5, 2018
    Inventors: Hans-Georg LERCHEN, Anne-Sophie REBSTOCK, Yolanda CANCHO GRANDE, Sven WITTROCK, Uwe GRITZAN, Pedro PAZ, Melanie FISCHER, Juergen FRANZ, Julian Marius GLÜCK, Stephan MÄRSCH, Beatrix STELTE-LUDWIG, Christoph MAHLERT, Ernst WEBER, Simone GREVEN, Sandra BERNDT